Compressive Stress Induces Dephosphorylation of the Myosin Regulatory Light Chain via RhoA Phosphorylation by the Adenylyl Cyclase/Protein Kinase A Signaling Pathway

cAMP signaling regulates platelet myosin light chain (MLC) phosphorylation and shape change through targeting the RhoA-Rho kinase-MLC phosphatase signaling pathway

(2013) A. Aburima et al.   BLOOD

A novel pathway spatiotemporally activates Rac1 and redox signaling in response to fluid shear stress

(2013) Yunhao Liu et al.   JOURNAL OF CELL BIOLOGY

Rac function is crucial for cell migration but is not required for spreading and focal adhesion formation

(2013) A. Steffen et al.   JOURNAL OF CELL SCIENCE

Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia

(2012) George T. Eisenhoffer et al.   NATURE

Active fluctuation in the cortical cytoskeleton observed by high-speed live-cell scanning probe microscopy

(2011) Kazushi Tamura et al.   Acta Biomaterialia

Actin filaments function as a tension sensor by tension-dependent binding of cofilin to the filament

(2011) Kimihide Hayakawa et al.   JOURNAL OF CELL BIOLOGY

Phasic contractions of isolated human myometrium are associated with Rho-kinase (ROCK)-dependent phosphorylation of myosin phosphatase-targeting subunit (MYPT1)

(2011) C. A. Hudson et al.   MOLECULAR HUMAN REPRODUCTION

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

The Rho GEFs LARG and GEF-H1 regulate the mechanical response to force on integrins

(2011) Christophe Guilluy et al.   NATURE CELL BIOLOGY

Modular Structure of Smooth Muscle Myosin Light Chain Kinase: Hydrodynamic Modeling and Functional Implications

(2010) Yasuko Mabuchi et al.   BIOCHEMISTRY

Cell Blebbing and Membrane Area Homeostasis in Spreading and Retracting Cells

(2010) Leann L. Norman et al.   BIOPHYSICAL JOURNAL

Primary cilium-dependent mechanosensing is mediated by adenylyl cyclase 6 and cyclic AMP in bone cells

(2010) Ronald Y. Kwon et al.   FASEB JOURNAL

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

Regulation by Ca2+-Signaling Pathways of Adenylyl Cyclases

(2010) M. L. Halls et al.   Cold Spring Harbor Perspectives in Biology

Phosphorylation-dependent Autoinhibition of Myosin Light Chain Phosphatase Accounts for Ca2+Sensitization Force of Smooth Muscle Contraction

(2009) Alexander Khromov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coordination of Rho GTPase activities during cell protrusion

(2009) Matthias Machacek et al.   NATURE

Regulation of cellular contractile force in response to mechanical stretch by diphosphorylation of myosin regulatory light chain via RhoA signaling cascade

(2009) Takeomi Mizutani et al.   CELL MOTILITY AND THE CYTOSKELETON

Mechanical Response to Isotropic Shrinkage of Fibroblasts Measured by Scanning Probe Microscopy

(2008) Taisuke Kawamoto et al.   JAPANESE JOURNAL OF APPLIED PHYSICS

PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility

(2008) Yangmi Lim et al.   JOURNAL OF CELL BIOLOGY

FAK, PDZ-RhoGEF and ROCKII cooperate to regulate adhesion movement and trailing-edge retraction in fibroblasts

(2008) M. P. Iwanicki et al.   JOURNAL OF CELL SCIENCE

Activation and Inhibition of Adenylyl Cyclase Isoforms by Forskolin Analogs

(2008) C. Pinto et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Quantification of Cell Edge Velocities and Traction Forces Reveals Distinct Motility Modules during Cell Spreading

(2008) Benjamin J. Dubin-Thaler et al.   PLoS One