Single Amino Acid Change in STING Leads to Constitutive Active Signaling
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Title
Single Amino Acid Change in STING Leads to Constitutive Active Signaling
Authors
Keywords
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Journal
PLoS One
Volume 10, Issue 3, Pages e0120090
Publisher
Public Library of Science (PLoS)
Online
2015-03-20
DOI
10.1371/journal.pone.0120090
References
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Related references
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- (2014) Xin Cai et al. MOLECULAR CELL
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- (2014) Yin Liu et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2014) Xu Zhang et al. Cell Reports
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- (2013) Pu Gao et al. CELL
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- (2013) Xin Li et al. IMMUNITY
- Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING
- (2013) Xu Zhang et al. MOLECULAR CELL
- Structural mechanism of cytosolic DNA sensing by cGAS
- (2013) Filiz Civril et al. NATURE
- Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity
- (2013) John W. Schoggins et al. NATURE
- Pivotal Roles of cGAS-cGAMP Signaling in Antiviral Defense and Immune Adjuvant Effects
- (2013) X.-D. Li et al. SCIENCE
- Cyclic GMP-AMP Synthase Is an Innate Immune Sensor of HIV and Other Retroviruses
- (2013) D. Gao et al. SCIENCE
- Structure of Human cGAS Reveals a Conserved Family of Second-Messenger Enzymes in Innate Immunity
- (2013) Philip J. Kranzusch et al. Cell Reports
- The Innate Immune DNA Sensor cGAS Produces a Noncanonical Cyclic Dinucleotide that Activates Human STING
- (2013) Elie J. Diner et al. Cell Reports
- Structural Analysis of the STING Adaptor Protein Reveals a Hydrophobic Dimer Interface and Mode of Cyclic di-GMP Binding
- (2012) Songying Ouyang et al. IMMUNITY
- Autoimmunity Initiates in Nonhematopoietic Cells and Progresses via Lymphocytes in an Interferon-Dependent Autoimmune Disease
- (2012) Alevtina Gall et al. IMMUNITY
- The structural basis for the sensing and binding of cyclic di-GMP by STING
- (2012) Yi-He Huang et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- STING manifests self DNA-dependent inflammatory disease
- (2012) J. Ahn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
- (2012) L. Sun et al. SCIENCE
- STING Specifies IRF3 Phosphorylation by TBK1 in the Cytosolic DNA Signaling Pathway
- (2012) Y. Tanaka et al. Science Signaling
- Identification and characterization of a loss-of-function human MPYS variant
- (2011) L Jin et al. GENES AND IMMUNITY
- MPYS Is Required for IFN Response Factor 3 Activation and Type I IFN Production in the Response of Cultured Phagocytes to Bacterial Second Messengers Cyclic-di-AMP and Cyclic-di-GMP
- (2011) L. Jin et al. JOURNAL OF IMMUNOLOGY
- STING is a direct innate immune sensor of cyclic di-GMP
- (2011) Dara L. Burdette et al. NATURE
- MAVS Self-Association Mediates Antiviral Innate Immune Signaling
- (2009) E. D. Tang et al. JOURNAL OF VIROLOGY
- ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization
- (2009) W. Sun et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation
- (2008) Bo Zhong et al. IMMUNITY
- MPYS, a Novel Membrane Tetraspanner, Is Associated with Major Histocompatibility Complex Class II and Mediates Transduction of Apoptotic Signals
- (2008) L. Jin et al. MOLECULAR AND CELLULAR BIOLOGY
- STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
- (2008) Hiroki Ishikawa et al. NATURE
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