Combinations of Ashwagandha Leaf Extracts Protect Brain-Derived Cells against Oxidative Stress and Induce Differentiation

Identification and Functional Characterization of Nuclear Mortalin in Human Carcinogenesis

(2014) Jihoon Ryu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myeloid-derived suppressor cell function is reduced by Withaferin A, a potent and abundant component of Withania somnifera root extract

(2013) Pratima Sinha et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Withanone as an inhibitor of survivin: A potential drug candidate for cancer therapy

(2013) Varsha P. Wadegaonkar et al.   JOURNAL OF BIOTECHNOLOGY

Withaferin A, a Steroidal Lactone from Withania somnifera, Induces Mitotic Catastrophe and Growth Arrest in Prostate Cancer Cells

(2013) Ram V. Roy et al.   JOURNAL OF NATURAL PRODUCTS

Metabolic Alterations in Mammary Cancer Prevention by Withaferin A in a Clinically Relevant Mouse Model

(2013) Eun-Ryeong Hahm et al.   JNCI-Journal of the National Cancer Institute

Involvement of hippocampal Arc in amnesia and its recovery by alcoholic extract of Ashwagandha leaves

(2013) Akash Gautam et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Withania somnifera Water Extract as a Potential Candidate for Differentiation Based Therapy of Human Neuroblastomas

(2013) Hardeep Kataria et al.   PLoS One

Water Extract of Ashwagandha Leaves Has Anticancer Activity: Identification of an Active Component and Its Mechanism of Action

(2013) Renu Wadhwa et al.   PLoS One

Withaferin A-induced apoptosis in human breast cancer cells is associated with suppression of inhibitor of apoptosis family protein expression

(2012) Eun-Ryeong Hahm et al.   CANCER LETTERS

Are oxidative stress and mitochondrial dysfunction the key players in the neurodegenerative diseases?

(2012) Marta Di Carlo et al.   FREE RADICAL RESEARCH

Ashwagandha Derived Withanone Targets TPX2-Aurora A Complex: Computational and Experimental Evidence to its Anticancer Activity

(2012) Abhinav Grover et al.   PLoS One

Water Extract from the Leaves of Withania somnifera Protect RA Differentiated C6 and IMR-32 Cells against Glutamate-Induced Excitotoxicity

(2012) Hardeep Kataria et al.   PLoS One

Potentiation of NMDA Receptor-Dependent Cell Responses by Extracellular High Mobility Group Box 1 Protein

(2012) Marco Pedrazzi et al.   PLoS One

Differential Activities of the Two Closely Related Withanolides, Withaferin A and Withanone: Bioinformatics and Experimental Evidences

(2012) Kirti Vaishnavi et al.   PLoS One

Withanone binds to mortalin and abrogates mortalin–p53 complex: Computational and experimental evidence

(2011) Abhinav Grover et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Withaferin A inhibits breast cancer invasion and metastasis at sub-cytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation

(2011) Jose T. Thaiparambil et al.   INTERNATIONAL JOURNAL OF CANCER

Glutamate and ATP signalling in white matter pathology

(2011) Carlos Matute   JOURNAL OF ANATOMY

Ashwagandha Leaf Derived Withanone Protects Normal Human Cells Against the Toxicity of Methoxyacetic Acid, a Major Industrial Metabolite

(2011) Didik Priyandoko et al.   PLoS One

Withaferin A-Induced Apoptosis in Human Breast Cancer Cells Is Mediated by Reactive Oxygen Species

(2011) Eun-Ryeong Hahm et al.   PLoS One

Nuclear GRP75 Binds Retinoic Acid Receptors to Promote Neuronal Differentiation of Neuroblastoma

(2011) Yu-Yin Shih et al.   PLoS One

Protective Role of Ashwagandha Leaf Extract and Its Component Withanone on Scopolamine-Induced Changes in the Brain and Brain-Derived Cells

(2011) Arpita Konar et al.   PLoS One

Chronic restraint stress alters the expression and distribution of phosphorylated tau and MAP2 in cortex and hippocampus of rat brain

(2010) Jie Yan et al.   BRAIN RESEARCH

Cytoprotective effects of vitamin E homologues against glutamate-induced cell death in immature primary cortical neuron cultures: Tocopherols and tocotrienols exert similar effects by antioxidant function

(2010) Yoshiro Saito et al.   FREE RADICAL BIOLOGY AND MEDICINE

Kainic Acid-Induced Neurodegenerative Model: Potentials and Limitations

(2010) Xiang-Yu Zheng et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

γH2AX: a sensitive molecular marker of DNA damage and repair

(2010) L-J Mah et al.   LEUKEMIA

Do astrocytes really exocytose neurotransmitters?

(2010) Nicola B. Hamilton et al.   NATURE REVIEWS NEUROSCIENCE

Selective Killing of Cancer Cells by Ashwagandha Leaf Extract and Its Component Withanone Involves ROS Signaling

(2010) Nashi Widodo et al.   PLoS One

Withaferin A targets heat shock protein 90 in pancreatic cancer cells

(2009) Yanke Yu et al.   BIOCHEMICAL PHARMACOLOGY

Effect of the alcoholic extract of Ashwagandha leaves and its components on proliferation, migration, and differentiation of glioblastoma cells: Combinational approach for enhanced differentiation

(2009) Navjot Shah et al.   CANCER SCIENCE

Oxidative Stress and Neurodegenerative Diseases: A Review of Upstream and Downstream Antioxidant Therapeutic Options

(2009) Bayani Uttara et al.   Current Neuropharmacology

Immune modulation and apoptosis induction: Two sides of antitumoural activity of a standardised herbal formulation of Withania somnifera

(2009) Fayaz Malik et al.   EUROPEAN JOURNAL OF CANCER

Water Extract of Ashwagandha Leaves Limits Proliferation and Migration, and Induces Differentiation in Glioma Cells

(2009) Hardeep Kataria et al.   Evidence-based Complementary and Alternative Medicine

Deceleration of Senescence in Normal Human Fibroblasts by Withanone Extracted From Ashwagandha Leaves

(2009) N. Widodo et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Long-term exposure to endogenous levels of tributyltin decreases GluR2 expression and increases neuronal vulnerability to glutamate

(2009) Yusuke Nakatsu et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Selective killing of cancer cells by leaf extract of Ashwagandha: Components, activity and pathway analyses

(2008) Nashi Widodo et al.   CANCER LETTERS

Withania somnifera: An Indian ginseng

(2007) S.K. Kulkarni et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY