GLUT4 Defects in Adipose Tissue Are Early Signs of Metabolic Alterations in Alms1GT/GT, a Mouse Model for Obesity and Insulin Resistance

Basal body proteins regulate Notch signaling through endosomal trafficking

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Mutations in Alström protein impair terminal differentiation of cardiomyocytes

(2014) Lincoln T. Shenje et al.   Nature Communications

Deletion of Rab GAP AS160 modifies glucose uptake and GLUT4 translocation in primary skeletal muscles and adipocytes and impairs glucose homeostasis

(2012) Melissa N. Lansey et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

AS160 deficiency causes whole-body insulin resistance via composite effects in multiple tissues

(2012) Hong Yu Wang et al.   BIOCHEMICAL JOURNAL

Hyperinsulinemia Drives Diet-Induced Obesity Independently of Brain Insulin Production

(2012) Arya E. Mehran et al.   Cell Metabolism

A truncating mutation of Alms1 reduces the number of hypothalamic neuronal cilia in obese mice

(2012) Déborah Heydet et al.   Developmental Neurobiology

Cold-induced activation of brown adipose tissue and adipose angiogenesis in mice

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Regulation of glucose transport by insulin: traffic control of GLUT4

(2012) Dara Leto et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Alström Syndrome Protein, ALMS1, Interacts with α-Actinin and Components of the Endosome Recycling Pathway

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Adipogenic potential of skeletal muscle satellite cells

(2011) Marta Sanna et al.   Clinical Lipidology

Adipose tissue remodeling and obesity

(2011) Kai Sun et al.   JOURNAL OF CLINICAL INVESTIGATION

The progression from obesity to type 2 diabetes in Alström syndrome

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Presentation and course of diabetes in children and adolescents with Alstrom syndrome

(2011) Arati Mokashi et al.   PEDIATRIC DIABETES

ALMS1-Deficient Fibroblasts Over-Express Extra-Cellular Matrix Components, Display Cell Cycle Delay and Are Resistant to Apoptosis

(2011) Elisabetta Zulato et al.   PLoS One

Hyperinsulinemia leads to uncoupled insulin regulation of the GLUT4 glucose transporter and the FoxO1 transcription factor

(2011) E. Gonzalez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Knockdown of the Alström syndrome-associated gene Alms1 in 3T3-L1 preadipocytes impairs adipogenesis but has no effect on cell-autonomous insulin action

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Increased adipogenic conversion of muscle satellite cells in obese Zucker rats

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Lipodystrophy: metabolic insights from a rare disorder

(2010) Isabel Huang-Doran et al.   JOURNAL OF ENDOCRINOLOGY

A Novel Role for the Centrosomal Protein, Pericentrin, in Regulation of Insulin Secretory Vesicle Docking in Mouse Pancreatic β-cells

(2010) Agata Jurczyk et al.   PLoS One

Requirement of Bardet-Biedl syndrome proteins for leptin receptor signaling

(2009) Seongjin Seo et al.   HUMAN MOLECULAR GENETICS

Hypertrophy and/or Hyperplasia: Dynamics of Adipose Tissue Growth

(2009) Junghyo Jo et al.   PLoS Computational Biology

Emerging role for AS160/TBC1D4 and TBC1D1 in the regulation of GLUT4 traffic

(2008) Kei Sakamoto et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

α-Actinin-4 Is Selectively Required for Insulin-induced GLUT4 Translocation

(2008) Ilana Talior-Volodarsky et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Mouse Model of Metabolic Syndrome; Increase in Visceral Adipose Tissue Precedes the Development of Fatty Liver and Insulin Resistance in High-Fat Diet-Fed Male KK/Ta Mice

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