Mitochondrial DNA (mtDNA) Haplogroups Influence the Progression of Knee Osteoarthritis. Data from the Osteoarthritis Initiative (OAI)

Mitochondrial Pathology in Osteoarthritic Chondrocytes

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Role of mtDNA Haplogroups in the Prevalence of Knee Osteoarthritis in a Southern Chinese Population

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mtDNA haplogroups and osteoarthritis in different geographic populations

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Molecular and bioenergetic differences between cells with African versus European inherited mitochondrial DNA haplogroups: Implications for population susceptibility to diseases

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Mitochondrial respiratory chain dysfunction modulates metalloproteases -1, -3 and -13 in human normal chondrocytes in culture

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IL-1 receptor antagonist gene as a predictive biomarker of progression of knee osteoarthritis in a population cohort

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Mitochondrial DNA Variants Mediate Energy Production and Expression Levels for CFH, C3 and EFEMP1 Genes: Implications for Age-Related Macular Degeneration

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No evidence of an association between mitochondrial DNA variants and osteoarthritis in 7393 cases and 5122 controls

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Quantitative MRI measures of cartilage predict knee replacement: a case–control study from the Osteoarthritis Initiative

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Mitochondrial dysfunction increases inflammatory responsiveness to cytokines in normal human chondrocytes

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Mitochondrial dysfunction in osteoarthritis is associated with down-regulation of superoxide dismutase 2

(2012) Christos Gavriilidis et al.   ARTHRITIS AND RHEUMATISM

Recent advances in osteoarthritis imaging—the Osteoarthritis Initiative

(2012) Felix Eckstein et al.   Nature Reviews Rheumatology

Functional Differences between Mitochondrial Haplogroup T and Haplogroup H in HEK293 Cybrid Cells

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mtDNA haplogroup J Modulates telomere length and Nitric Oxide production

(2011) Mercedes Fernández-Moreno et al.   BMC MUSCULOSKELETAL DISORDERS

The role of mitochondria in osteoarthritis

(2011) Francisco J. Blanco et al.   Nature Reviews Rheumatology

Mitochondrial DNA haplogroups and serum levels of proteolytic enzymes in patients with osteoarthritis

(2010) I. Rego-Perez et al.   ANNALS OF THE RHEUMATIC DISEASES

Unmasking the causes of multifactorial disorders: OXPHOS differences between mitochondrial haplogroups

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Genetic epidemiology of hip and knee osteoarthritis

(2010) Ana M. Valdes et al.   Nature Reviews Rheumatology

Large-scale meta-analysis of interleukin-1 beta and interleukin-1 receptor antagonist polymorphisms on risk of radiographic hip and knee osteoarthritis and severity of knee osteoarthritis

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One-year change in radiographic joint space width in patients with unilateral joint space narrowing: Data from the osteoarthritis initiative

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Prediction model for knee osteoarthritis based on genetic and clinical information

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Mitochondrial DNA haplogroups modulate the serum levels of biomarkers in patients with osteoarthritis

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Radiographic severity of knee osteoarthritis is conditional on interleukin 1 receptor antagonist gene variations

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Role of European mitochondrial DNA haplogroups in the prevalence of hip osteoarthritis in Galicia, Northern Spain

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Sensitivity to change of cartilage morphometry using coronal FLASH, sagittal DESS, and coronal MPR DESS protocols – comparative data from the osteoarthritis initiative (OAI)

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Head-to-head comparison of the Lyon Schuss and fixed flexion radiographic techniques. Long-term reproducibility in normal knees and sensitivity to change in osteoarthritic knees

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One year change of knee cartilage morphology in the first release of participants from the Osteoarthritis Initiative progression subcohort: association with sex, body mass index, symptoms and radiographic osteoarthritis status

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Mitochondrial dysfunction activates cyclooxygenase 2 expression in cultured normal human chondrocytes

(2008) Berta Cillero-Pastor et al.   ARTHRITIS AND RHEUMATISM

Mitochondrial DNA haplogroups: Role in the prevalence and severity of knee osteoarthritis

(2008) Ignacio Rego-Pérez et al.   ARTHRITIS AND RHEUMATISM

Association of mitochondrial haplogroup J and mtDNA oxidative damage in two different North Spain elderly populations

(2008) Elena Domínguez-Garrido et al.   BIOGERONTOLOGY

Genetics in Osteoarthritis

(2008) Mercedes Fernandez-Moreno et al.   CURRENT GENOMICS

Diminished mitochondrial DNA integrity and repair capacity in OA chondrocytes

(2008) V.I. Grishko et al.   OSTEOARTHRITIS AND CARTILAGE

Regional analysis of femorotibial cartilage loss in a subsample from the Osteoarthritis Initiative progression subcohort

(2008) W. Wirth et al.   OSTEOARTHRITIS AND CARTILAGE

Common interleukin-6 promoter variants associate with the more severe forms of distal interphalangeal osteoarthritis

(2008) Olli-Pekka Kämäräinen et al.   ARTHRITIS RESEARCH & THERAPY