Article
Oncology
Loic Vander Veken, Genevieve Van Ooteghem, Ariane Razavi, Sergio Da Rita Quaresma, Eleonore Longton, Carine Kirkove, Benjamin Ledoux, Ad Vandermeulen, Christel Abdel Massih, Pascale Henderickx, Mortimer Gabriels, Celine Delvaux, Faycal Salah, Aude Vaandering, Xavier Geets
Summary: This study compared the effects of mechanically-induced DIBH and SGRT-guided voluntary DIBH in breast radiotherapy. The results showed that mechanically-induced DIBH performed better in protecting and repositioning critical organs while achieving similar target irradiation accuracy as SGRT.
RADIOTHERAPY AND ONCOLOGY
(2023)
Article
Critical Care Medicine
Robert J. Stephens, Erin M. Evans, Michael J. Pajor, Ryan D. Pappal, Haley M. Egan, Max Wei, Hunter Hayes, Jason A. Morris, Nicholas Becker, Brian W. Roberts, Marin H. Kollef, Nicholas M. Mohr, Brian M. Fuller
Summary: Mechanically ventilated patients have experienced longer periods of deep sedation during the COVID-19 pandemic. Early deep sedation is associated with higher mortality and shorter ventilator, ICU, and hospital-free days. However, there is a lack of data on sedation depth and outcomes during the COVID-19 pandemic.
Article
Radiology, Nuclear Medicine & Medical Imaging
Xuzhe Zhang, Elsa D. Angelini, Fateme S. Haghpanah, Andrew F. Laine, Yanping Sun, Grant T. Hiura, Stephen M. Dashnaw, Martin R. Prince, Eric A. Hoffman, Bharath Ambale-Venkatesh, Joao A. Lima, Jim M. Wild, Emlyn W. Hughes, R. Graham Barr, Wei Shen
Summary: The purpose of this study was to develop a deep learning framework for segmenting ventilation defects on pulmonary hyperpolarized MRI. Traditional U-Net and cascaded U-Net algorithms were used for segmentation, and conventional data augmentation was employed to improve the segmentation results.
MAGNETIC RESONANCE IMAGING
(2022)
Article
Engineering, Environmental
Jaewon Lee, Sunghyun Cho, Hyungtae Cho, Seungsik Cho, Inkyu Lee, Il Moon, Junghwan Kim
Summary: Hydrogen fuel cells have been installed in over 100 facilities and numerous homes in the hydrogen town of Ulsan, Republic of Korea. While hydrogen has its advantages, accidents near residential areas can still occur, so it is necessary to establish appropriate risk mitigation plans. This study presents a computational fluid dynamics (CFD) model to address emergency responses to hydrogen leaks in pressure regulator equipment housing. The results indicate that a specific vent configuration, UP-DOWN, achieves the lowest internal hydrogen concentration. Furthermore, the relationship between total vent size and internal hydrogen concentration is determined, and the use of nitrogen for forced ventilation during emergencies is proposed for safety.
PROCESS SAFETY AND ENVIRONMENTAL PROTECTION
(2022)
Article
Chemistry, Multidisciplinary
Jincheng Ji, Kun Wang, Simin Zhu, Weihua Zhu
Summary: The study shows that as the impurity concentration in the crystal increases, the stability decreases and impurity molecules tend to form aggregates, leading to a significant decrease in the band gap of the NTO crystal with increasing impurity content.
Article
Construction & Building Technology
James A. McGrath, Reihaneh Aghamolaei, James O'Donnell, Miriam A. Byrne
Summary: Recent research indicates that radon levels may increase following energy retrofitting of naturally ventilated dwellings, primarily due to increased airtightness of the building. The simulations also show that factors such as indoor temperature and weather conditions can impact radon concentration.
BUILDING AND ENVIRONMENT
(2021)
Article
Anesthesiology
Heejoon Jeong, Pisitpitayasaree Tanatporn, Hyun Joo Ahn, Mikyung Yang, Jie Ae Kim, Hyean Yeo, Woojin Kim
Summary: The study showed that pressure support ventilation during emergence from anesthesia reduced the incidence of postoperative atelectasis in patients undergoing laparoscopic surgery. Patients who received pressure support ventilation had better lung function and oxygenation status postoperatively compared to those who received intermittent manual assistance.
Article
Physics, Condensed Matter
Giordano F. C. Bispo, Debora S. Nascimento, Lucas B. Santana, Gilvan S. Ferreira, Zelia S. Macedo, Hestia R. B. R. Lima, Susana O. Souza, Francesco d'Errico, Robert A. Jackson, Mario E. G. Valerio
Summary: Lanthanide-doped MgB4O7 is a potential dosimetric material with thermoluminescence and optically stimulated luminescence properties. This study emphasizes the importance of defects in understanding the luminescence mechanisms and proposes two possible doping schemes for lanthanide ions.
PHYSICA B-CONDENSED MATTER
(2022)
Article
Pediatrics
Chao Yang, Jiang Li, Huo Li, Nan Chen, Xing Yin, Bing Shi, Jingtao Li, Hanyao Huang
Summary: This study used computational fluid dynamics to examine the airflow dynamics of the upper airway after posterior pharyngeal flap palatoplasty (PPF). The results showed that the inspiration process of the upper airway was dependent on the velopharyngeal structure, with different velocities between one-port and two-port structures. Based on the CFD analyses, it was suggested that the one-port structure might be a better choice for secondary velopharyngeal insufficiency reconstruction.
FRONTIERS IN PEDIATRICS
(2022)
Article
Construction & Building Technology
Hao-Hsiang Hsu, Wei-Hwa Chiang, Jian-Sheng Huang
Summary: The study compared the effectiveness of stack and displacement ventilation in providing thermal comfort in an air-conditioned office building through computational fluid dynamics simulations. Displacement ventilation was found to perform better, especially with a higher ceiling, heat source, and lower inlet with cold air. Handrails near the atrium were also noted to play a crucial role in retaining cold air for a longer period, contributing to improved thermal comfort.
Article
Physics, Applied
Kazutaka Kanegae, Takafumi Okuda, Masahiro Horita, Jun Suda, Tsunenobu Kimoto
Summary: Investigation of electron traps generated during the reactive ion etching process in n-type 4H-SiC was conducted using deep-level transient spectroscopy and isothermal capacitance transient spectroscopy techniques. A method for determining the depth profiles of electron traps near the etched surface was proposed, resulting in a depth profile extraction with higher resolution than traditional methods.
JOURNAL OF APPLIED PHYSICS
(2021)
Article
Medicine, General & Internal
Jesus Burgos, Carlos Barrios, Gonzalo Mariscal, Alejandro Lorente, Rafael Lorente
Summary: The study analyzed the range of motion of the thoracic spine by measuring changes in the sagittal profile of different thoracic segments during maximal inspiration and exhalation. Results showed that the flexibility of the thoracic spine during deep breathing was wider in the caudal hemicurve than in the cranial hemicurve, with angular movements of the T7-T10 segment playing a significant role in maximal inspiration.
FRONTIERS IN MEDICINE
(2021)
Article
Engineering, Environmental
Wei Yang, Wenxiao Zhang, Baiquan Lin, Guangyao Si, Jianguo Zhang, Jianli Wang
Summary: The paper demonstrated a novel integrated mining system in the 12th coal mine of the Pingdingshan coalfield, which extracted two panels simultaneously to effectively mine thin protective coal seams and control gas outbursts. This system not only increased mining efficiency, but also reduced surface mining footprint and cost of gangue handling.
PROCESS SAFETY AND ENVIRONMENTAL PROTECTION
(2022)
Article
Chemistry, Multidisciplinary
Yuhua Zhu, Hang Li, Tong Zhen, Zhihui Li
Summary: This paper proposes a grain condition multimodal approach based on the theory of computer multimodality, which studies intelligent ventilation decisions to achieve grain temperature balance, prevent moisture condensation, control grain heating, reduce grain moisture, and create a low-temperature environment to improve grain storage performance.
APPLIED SCIENCES-BASEL
(2023)
Article
Hematology
Elizabeth E. Havlicek, Zachary A. Goldman, Edward Vincent S. Faustino, Vera Ignjatovic, Neil A. Goldenberg, Anthony A. Sochet
Summary: This retrospective cohort study found that critically ill children undergoing invasive mechanical ventilation have a higher frequency of hospital-acquired venous thromboembolism (HA-VTE) compared to the general pediatric intensive care unit population. These findings are important for informing the development of risk-stratified thromboprophylaxis trials in critically ill children.
JOURNAL OF THROMBOSIS AND HAEMOSTASIS
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Takuga Hinoshita, Gabriel Motta Ribeiro, Tilo Winkler, Nicolas de Prost, Mauro R. Tucci, Eduardo Leite Vieira Costa, Tyler J. Wellman, Soshi Hashimoto, Congli Zeng, Alysson R. Carvalho, Marcos Francisco Vidal Melo
ACADEMIC RADIOLOGY
(2020)
Letter
Critical Care Medicine
Jason H. Maley, Tilo Winkler, C. Corey Hardin
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
(2020)
Article
Anesthesiology
Congli Zeng, Gabriel C. Motta-Ribeiro, Takuga Hinoshita, Marcos Adriano Lessa, Tilo Winkler, Kira Grogg, Nathan M. Kingston, John N. Hutchinson, Lynette Marie Sholl, Xiangming Fang, Xaralabos Varelas, Matthew D. Layne, Rebecca M. Baron, Marcos F. Vidal Melo
Article
Radiology, Nuclear Medicine & Medical Imaging
Puja Kohli, Vanessa J. Kelly, Kathryn A. Hibbert, Bjorn Corleis, Mamary Kone, Josalyn L. Cho, Doreen DeFaria-Yeh, Douglas S. Kwon, Benjamin D. Medoff, R. Scott Harris, Tilo Winkler
Summary: In this study, researchers used PET/CT technology to examine 46 smokers and non-smokers, including 23 with known HIV infection. The results showed that non-smokers living with HIV had more prominent abnormalities in pulmonary perfusion compared to the control group, suggesting similarities to smokers.
JOURNAL OF NUCLEAR MEDICINE
(2021)
Article
Anesthesiology
Alessandro Beda, Tilo Winkler, Tyler J. Wellman, Nicolas De Prost, Mauro Tucci, Marcos F. Vidal Melo
Summary: In this early ARDS model, increased alveolar dead-space occurs within 20 hours due to the regional redistribution of perfusion, not ventilation. This moderate redistribution suggests changes in the interplay between active and passive perfusion redistribution mechanisms, not the appearance of thromboembolism. The association between mortality and increased dead-space possibly arises from the former, reflecting gas-exchange inefficiency due to perfusion heterogeneity.
ACTA ANAESTHESIOLOGICA SCANDINAVICA
(2021)
Editorial Material
Physiology
Gabriel C. Motta-Ribeiro, Tilo Winkler
JOURNAL OF APPLIED PHYSIOLOGY
(2020)
Article
Radiology, Nuclear Medicine & Medical Imaging
Delphine L. Chen, Safia Ballout, Laigao Chen, Joseph Cheriyan, Gourab Choudhury, Ana M. Denis-Bacelar, Elise Emond, Kjell Erlandsson, Marie Fisk, Francesco Fraioli, Ashley M. Groves, Roger N. Gunn, Jun Hatazawa, Beverley F. Holman, Brian F. Hutton, Hidehiro Iida, Sarah Lee, William MacNee, Keiko Matsunaga, Divya Mohan, David Parr, Alaleh Rashidnasab, Gaia Rizzo, Deepak Subramanian, Ruth Tal-Singer, Kris Thielemans, Nicola Tregay, Edwin J. R. van Beek, Laurence Vass, Marcos F. Vidal Melo, Jeremy W. Wellen, Ian Wilkinson, Frederick J. Wilson, Tilo Winkler
JOURNAL OF NUCLEAR MEDICINE
(2020)
Article
Biochemistry & Molecular Biology
Bjorn Corleis, Josalyn L. Cho, Samantha J. Gates, Alice H. Linder, Amy Dickey, Antonella C. Lisanti-Park, Abigail E. Schiff, Musie Ghebremichael, Puja Kohli, Tilo Winkler, R. Scott Harris, Benjamin D. Medoff, Douglas S. Kwon
Summary: HIV-1 infection and smoking can lead to an accumulation of CD8(+) T cells within the airway mucosa, affecting the progression of COPD in at-risk patients.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
(2021)
Editorial Material
Allergy
Tilo Winkler, Urs Frey
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
(2021)
Article
Chemistry, Analytical
Paul Meaney, Shireen Geimer, Amir Golnabi, Keith Paulsen
Summary: This paper investigates the effects of skin on breast imaging and finds that the impact of skin is minor when using transmission-based measurement data and lossy coupling materials.
Article
Physiology
Gabriel C. Motta-Ribeiro, Tilo Winkler, Eduardo L. V. Costa, Nicolas de Prost, Mauro R. Tucci, Marcos F. Vidal Melo
Summary: Lung perfusion redistribution is associated with increased inflammation, nondependent capillary obliteration, and lung derecruitment susceptibility depending on endotoxemia level and ventilation strategy during pre-ARDS protective ventilation in animals.
JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Article
Physiology
Yi Xin, Taehwan Kim, Tilo Winkler, Gunnar Brix, Timothy Gaulton, Sarah E. Gerard, Jacob Herrmann, Kevin T. Martin, Marcus Victor, Kristan Reutlinger, Marcelo Amato, Lorenzo Berra, Mannudeep K. Kalra, Maurizio Cereda
Summary: This study compares different injection protocols and tracer-kinetic analysis models to optimize the measurement of pulmonary blood flow using dynamic contrast-enhanced computed tomography, providing insights into how acute respiratory distress syndrome alters pulmonary perfusion.
JOURNAL OF APPLIED PHYSIOLOGY
(2023)
Article
Respiratory System
Tilo Winkler, Puja Kohli, Vanessa J. Kelly, Ekaterina G. Kehl, Alison S. Witkin, Josanna M. Rodriguez-Lopez, Kathryn A. Hibbert, Mamary T. Kone, David M. Systrom, Aaron B. Waxman, Jose G. Venegas, Richard N. Channick, R. Scott Harris
Summary: Perfusion imaging during O2 + iNO showed significant differences in the heterogeneity associated with the vertical gradient in perfusion, distinguishing PAH subjects from controls in this small cohort study.
RESPIRATORY RESEARCH
(2022)
Letter
Physiology
Tilo Winkler
JOURNAL OF APPLIED PHYSIOLOGY
(2021)
Meeting Abstract
Infectious Diseases
P. Kohli, M. Kone, V. Kelly, K. Hibbert, B. Corleis, J. Cho, D. Kwon, B. Medoff, S. Harris, T. Winkler