Systemically Administered IgG Anti-Toxin Antibodies Protect the Colonic Mucosa during Infection with Clostridium difficile in the Piglet Model

Treatment approaches including fecal microbiota transplantation for recurrent Clostridium difficile infection (RCDI) among infectious disease physicians

(2013) Johan S. Bakken et al.   ANAEROBE

Detection, Treatment, and Prevention of Clostridium difficile Infection

(2012) David L. McCollum et al.   Clinical Gastroenterology and Hepatology

The Immunologic Functions of the Neonatal Fc Receptor for IgG

(2012) Timo Rath et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Antibody Against TcdB, but Not TcdA, Prevents Development of Gastrointestinal and Systemic Clostridium difficile Disease

(2012) Jennifer Steele et al.   JOURNAL OF INFECTIOUS DISEASES

Systemic Dissemination of Clostridium difficile Toxins A and B Is Associated With Severe, Fatal Disease in Animal Models

(2011) Jennifer Steele et al.   JOURNAL OF INFECTIOUS DISEASES

Treatment with Monoclonal Antibodies againstClostridium difficileToxins

(2010) Israel Lowy et al.   NEW ENGLAND JOURNAL OF MEDICINE

Neutralizing antibodies to Shiga toxin type 2 (Stx2) reduce colonization of mice by Stx2-expressing Escherichia coli O157:H7

(2010) Krystle L. Mohawk et al.   VACCINE

Toxin-Specific Antibodies for the Treatment of Clostridium difficile: Current Status and Future Perspectives

(2010) Greg Hussack et al.   Toxins

The Enterotoxicity of Clostridium difficile Toxins

(2010) Xingmin Sun et al.   Toxins

Piglet Models of Acute or ChronicClostridium difficileIllness

(2009) Jennifer Steele et al.   JOURNAL OF INFECTIOUS DISEASES

Serum anti-toxin B antibody correlates with protection from recurrent Clostridium difficile infection (CDI)

(2009) Brett A. Leav et al.   VACCINE

Expression of recombinant Clostridium difficile toxin A and B in Bacillus megaterium

(2008) Guilin Yang et al.   BMC MICROBIOLOGY

Open-label, dose escalation phase I study in healthy volunteers to evaluate the safety and pharmacokinetics of a human monoclonal antibody to Clostridium difficile toxin A

(2008) Claribel P. Taylor et al.   VACCINE