Distinct Roles for Hematopoietic and Extra-Hematopoietic Sphingosine Kinase-1 in Inflammatory Bowel Disease

Epidermal growth factor-induced cellular invasion requires sphingosine-1-phosphate/sphingosine-1-phosphate 2 receptor-mediated ezrin activation

(2013) K. Alexa Orr Gandy et al.   FASEB JOURNAL

Sphingosine Kinase 1 Is Regulated by Peroxisome Proliferator-activated Receptor α in Response to Free Fatty Acids and Is Essential for Skeletal Muscle Interleukin-6 Production and Signaling in Diet-induced Obesity

(2013) Jessica S. Ross et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neutrophil-Lymphocyte Ratio as a Predictor of Disease Severity in Ulcerative Colitis

(2013) Mehmet Celikbilek et al.   JOURNAL OF CLINICAL LABORATORY ANALYSIS

Sphingosine-1-Phosphate Links Persistent STAT3 Activation, Chronic Intestinal Inflammation, and Development of Colitis-Associated Cancer

(2012) Jie Liang et al.   CANCER CELL

Dietary supplementation of an ellagic acid-enriched pomegranate extract attenuates chronic colonic inflammation in rats

(2012) Maria Angeles Rosillo et al.   PHARMACOLOGICAL RESEARCH

Loss of neutral ceramidase increases inflammation in a mouse model of inflammatory bowel disease

(2012) Ashley J. Snider et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS

Assessment of neutrophil-lymphocyte ratio in ulcerative colitis: A promising marker in predicting disease severity

(2012) Serkan Torun et al.   Clinics and Research in Hepatology and Gastroenterology

Ceramide Synthase-dependent Ceramide Generation and Programmed Cell Death

(2011) Thomas D. Mullen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Defining a role for sphingosine kinase 1 in p53-dependent tumors

(2011) L A Heffernan-Stroud et al.   ONCOGENE

Dietary supplementation of resveratrol attenuates chronic colonic inflammation in mice

(2010) Susana Sánchez-Fidalgo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Sphingosine-1-phosphate Lyase Deficiency Produces a Pro-inflammatory Response While Impairing Neutrophil Trafficking

(2010) Maria L. Allende et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genetic Sphingosine Kinase 1 Deficiency Significantly Decreases Synovial Inflammation and Joint Erosions in Murine TNF- -Induced Arthritis

(2010) D. A. Baker et al.   JOURNAL OF IMMUNOLOGY

Sphingosine Kinase1 Is Pivotal for Fc RI-Mediated Mast Cell Signaling and Functional Responses In Vitro and In Vivo

(2009) P. N. Pushparaj et al.   JOURNAL OF IMMUNOLOGY

Incomplete Inhibition of Sphingosine 1-Phosphate Lyase Modulates Immune System Function yet Prevents Early Lethality and Non-Lymphoid Lesions

(2009) Peter Vogel et al.   PLoS One

Role for sphingosine kinase 1 in colon carcinogenesis

(2008) Toshihiko Kawamori et al.   FASEB JOURNAL

A role for sphingosine kinase 1 in dextran sulfate sodium-induced colitis

(2008) Ashley J. Snider et al.   FASEB JOURNAL

Interleukin-1 Regulates the Expression of Sphingosine Kinase 1 in Glioblastoma Cells

(2008) Barbara S. Paugh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ceramide accumulation mediates inflammation, cell death and infection susceptibility in cystic fibrosis

(2008) Volker Teichgräber et al.   NATURE MEDICINE