Long-Term Quiescent Fibroblast Cells Transit into Senescence

Be quiet and you'll keep young: does mTOR underlie p53 action in protecting against senescence by favoring quiescence?

(2016) Vjekoslav Dulic   Aging-US

Two-color fluorescence detection of Poly (ADP-Ribose) Polymerase-1 (PARP-1) cleavage and DNA strand breaks in etoposide-induced apoptotic cells

(2015) C Soldani et al.   EUROPEAN JOURNAL OF HISTOCHEMISTRY

The replicometer is broken: telomeres activate cellular senescence in response to genotoxic stresses

(2014) Anitha Suram et al.   AGING CELL

A genomics approach identifies senescence-specific gene expression regulation

(2014) Daniel H. Lackner et al.   AGING CELL

Quiescent Hematopoietic Stem Cells Accumulate DNA Damage during Aging that Is Repaired upon Entry into Cell Cycle

(2014) Isabel Beerman et al.   Cell Stem Cell

Crosstalk between the Rb Pathway and AKT Signaling Forms a Quiescence-Senescence Switch

(2014) Yoshinori Imai et al.   Cell Reports

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

An array of nuclear microtubules reorganizes the budding yeast nucleus during quiescence

(2013) Damien Laporte et al.   JOURNAL OF CELL BIOLOGY

H4K20 methylation regulates quiescence and chromatin compaction

(2013) Adam G. Evertts et al.   MOLECULAR BIOLOGY OF THE CELL

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

Loss of p16Ink4a Function Rescues Cellular Senescence Induced by Telomere Dysfunction

(2012) Xiufeng Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Status of mTOR activity may phenotypically differentiate senescence and quiescence

(2012) Sohee Cho et al.   MOLECULES AND CELLS

Quantitative Model of Cell Cycle Arrest and Cellular Senescence in Primary Human Fibroblasts

(2012) Sascha Schäuble et al.   PLoS One

Defective nuclear translocation of stress-activated signaling in senescent diploid human fibroblasts: a possible explanation for aging-associated apoptosis resistance

(2011) Sung Young Kim et al.   APOPTOSIS

Confluence-induced cell cycle exit involves pre-mitotic CDK inhibition by p27Kip1 and cyclin D1 downregulation

(2011) Anne-Amandine Chassot et al.   CELL CYCLE

Loss of p21CDKN1Aimpairs entry to quiescence and activates a DNA damage response in normal fibroblasts induced to quiescence

(2011) Paola Perucca et al.   CELL CYCLE

Triggering of a novel intrinsic apoptosis pathway by the kinase inhibitor staurosporine: activation of caspase-9 in the absence of Apaf-1

(2011) Joachim Manns et al.   FASEB JOURNAL

baySeq: Empirical Bayesian methods for identifying differential expression in sequence count data

(2010) Thomas J Hardcastle et al.   BMC BIOINFORMATICS

Dissecting the Unique Role of the Retinoblastoma Tumor Suppressor during Cellular Senescence

(2010) Agustin Chicas et al.   CANCER CELL

Stem Cells and DNA Damage: Persist or Perish?

(2010) Andrew A. Lane et al.   CELL

The p53 tumor suppressor protein regulates hematopoietic stem cell fate

(2010) Takashi Asai et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Senescent mesenchymal cells accumulate in human fibrosis by a telomere-independent mechanism and ameliorate fibrosis through matrix metalloproteinases

(2010) Gayani Nadika Pitiyage et al.   JOURNAL OF PATHOLOGY

Quiescent Fibroblasts Exhibit High Metabolic Activity

(2010) Johanna M. S. Lemons et al.   PLOS BIOLOGY

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

Cellular senescence: unravelling complexity

(2009) João F. Passos et al.   AGE

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

GAGE: generally applicable gene set enrichment for pathway analysis

(2009) Weijun Luo et al.   BMC BIOINFORMATICS

Hematopoietic Stem Cell Quiescence: Yet Another Role for p53

(2009) Ronald van Os et al.   Cell Stem Cell

p53 Regulates Hematopoietic Stem Cell Quiescence

(2009) Yan Liu et al.   Cell Stem Cell

Significant correlation of species longevity with DNA double strand break recognition but not with telomere length

(2009) Antonello Lorenzini et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Healing and Hurting: Molecular Mechanisms, Functions, and Pathologies of Cellular Senescence

(2009) Peter D. Adams   MOLECULAR CELL

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Aging and cancer cell biology, 2008

(2008) Judith Campisi   AGING CELL

Control of the Reversibility of Cellular Quiescence by the Transcriptional Repressor HES1

(2008) L. Sang et al.   SCIENCE