Boolean Modelling Reveals New Regulatory Connections between Transcription Factors Orchestrating the Development of the Ventral Spinal Cord

Morphogen interpretation: the transcriptional logic of neural tube patterning

(2013) Michael Cohen et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Temporal control of BMP signalling determines neuronal subtype identity in the dorsal neural tube

(2013) S. Tozer et al.   DEVELOPMENT

Gene Regulatory Logic for Reading the Sonic Hedgehog Signaling Gradient in the Vertebrate Neural Tube

(2012) Nikolaos Balaskas et al.   CELL

Mechanistic Differences in the Transcriptional Interpretation of Local and Long-Range Shh Morphogen Signaling

(2012) Tony Oosterveen et al.   DEVELOPMENTAL CELL

Autonomous Boolean modelling of developmental gene regulatory networks

(2012) X. Cheng et al.   Journal of the Royal Society Interface

Establishment of Motor Neuron-V3 Interneuron Progenitor Domain Boundary in Ventral Spinal Cord Requires Groucho-Mediated Transcriptional Corepression

(2012) Keith J. Todd et al.   PLoS One

Predictive computation of genomic logic processing functions in embryonic development

(2012) I. S. Peter et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nkx2.2 repressor complex regulates islet  -cell specification and prevents  -to- -cell reprogramming

(2011) J. B. Papizan et al.   GENES & DEVELOPMENT

Distinct Sonic Hedgehog signaling dynamics specify floor plate and ventral neuronal progenitors in the vertebrate neural tube

(2010) V. Ribes et al.   GENES & DEVELOPMENT

The Arabidopsis thaliana flower organ specification gene regulatory network determines a robust differentiation process

(2010) Yara-Elena Sánchez-Corrales et al.   JOURNAL OF THEORETICAL BIOLOGY

Attractor analysis of asynchronous Boolean models of signal transduction networks

(2010) Assieh Saadatpour et al.   JOURNAL OF THEORETICAL BIOLOGY

Using heterogeneous data sources in a systems biology approach to modeling the Sonic Hedgehog signaling pathway

(2010) Erin R. Boykin et al.   Molecular BioSystems

Dynamic Assignment and Maintenance of Positional Identity in the Ventral Neural Tube by the Morphogen Sonic Hedgehog

(2010) Eric Dessaud et al.   PLOS BIOLOGY

A Boolean Model of the Gene Regulatory Network Underlying Mammalian Cortical Area Development

(2010) Clare E. Giacomantonio et al.   PLoS Computational Biology

Modeling the spatio-temporal network that drives patterning in the vertebrate central nervous system

(2009) Yuichi Nishi et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Identification of known and novel pancreas genes expressed downstream of Nkx2.2 during development

(2009) Keith R Anderson et al.   BMC DEVELOPMENTAL BIOLOGY

Nkx2.2 Activates the Ghrelin Promoter in Pancreatic Islet Cells

(2009) Jonathon T. Hill et al.   MOLECULAR ENDOCRINOLOGY

Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3

(2009) A. Ragvin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Establishing and Interpreting Graded Sonic Hedgehog Signaling during Vertebrate Neural Tube Patterning: The Role of Negative Feedback

(2009) V. Ribes et al.   Cold Spring Harbor Perspectives in Biology

Spatial Analysis of Expression Patterns Predicts Genetic Interactions at the Mid-Hindbrain Boundary

(2009) Dominik M. Wittmann et al.   PLoS Computational Biology

Boolean Network Model Predicts Cell Cycle Sequence of Fission Yeast

(2008) Maria I. Davidich et al.   PLoS One

Directed Differentiation of Ventral Spinal Progenitors and Motor Neurons from Human Embryonic Stem Cells by Small Molecules

(2008) Xue-Jun Li et al.   STEM CELLS