Genetic Ablation of Afadin Causes Mislocalization and Deformation of Paneth Cells in the Mouse Small Intestinal Epithelium

The Intestinal Crypt, A Prototype Stem Cell Compartment

(2013) Hans Clevers   CELL

De novo lumen formation and elongation in the developing nephron: a central role for afadin in apical polarity

(2013) Z. Yang et al.   DEVELOPMENT

Cdc42 Coordinates Proliferation, Polarity, Migration, and Differentiation of Small Intestinal Epithelial Cells in Mice

(2013) Jaime Melendez et al.   GASTROENTEROLOGY

Binding between the Junctional Proteins Afadin and PLEKHA7 and Implication in the Formation of Adherens Junction in Epithelial Cells

(2013) Souichi Kurita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

An Adaptor Molecule Afadin Regulates Lymphangiogenesis by Modulating RhoA Activity in the Developing Mouse Embryo

(2013) Takashi Majima et al.   PLoS One

Genetic Deletion of Afadin Causes Hydrocephalus by Destruction of Adherens Junctions in Radial Glial and Ependymal Cells in the Midbrain

(2013) Hideaki Yamamoto et al.   PLoS One

Cdc42 and Rab8a are critical for intestinal stem cell division, survival, and differentiation in mice

(2012) Ryotaro Sakamori et al.   JOURNAL OF CLINICAL INVESTIGATION

Krüppel-like Factor 4 Regulates Intestinal Epithelial Cell Morphology and Polarity

(2012) Tianxin Yu et al.   PLoS One

Involvement of afadin in barrier function and homeostasis of mouse intestinal epithelia

(2011) M. Tanaka-Okamoto et al.   JOURNAL OF CELL SCIENCE

Paneth cells, antimicrobial peptides and maintenance of intestinal homeostasis

(2011) Charles L. Bevins et al.   NATURE REVIEWS MICROBIOLOGY

Role of Afadin in Vascular Endothelial Growth Factor– and Sphingosine 1-Phosphate–Induced Angiogenesis

(2010) Hideto Tawa et al.   CIRCULATION RESEARCH

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

(2010) Toshiro Sato et al.   NATURE

A Key Role for E-cadherin in Intestinal Homeostasis and Paneth Cell Maturation

(2010) Marlon R. Schneider et al.   PLoS One

Involvement of afadin in the formation and remodeling of synapses in the hippocampus

(2009) Takashi Majima et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

DCAMKL-1 Expression Identifies Tuft Cells Rather Than Stem Cells in the Adult Mouse Intestinal Epithelium

(2009) François Gerbe et al.   GASTROENTEROLOGY

Regulation by Afadin of Cyclical Activation and Inactivation of Rap1, Rac1, and RhoA Small G Proteins at Leading Edges of Moving NIH3T3 Cells

(2009) Muneaki Miyata et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Localization of nectin-free afadin at the leading edge and its involvement in directional cell movement induced by platelet-derived growth factor

(2009) M. Miyata et al.   JOURNAL OF CELL SCIENCE

Junctional Adhesion Molecule A Interacts with Afadin and PDZ-GEF2 to Activate Rap1A, Regulate β1 Integrin Levels, and Enhance Cell Migration

(2009) Eric A. Severson et al.   MOLECULAR BIOLOGY OF THE CELL

The Immunoglobulin-Like Cell Adhesion Molecule Nectin and Its Associated Protein Afadin

(2008) Yoshimi Takai et al.   Annual Review of Cell and Developmental Biology

Organization of multiprotein complexes at cell–cell junctions

(2008) Klaus Ebnet   HISTOCHEMISTRY AND CELL BIOLOGY

Nectins and nectin-like molecules: roles in contact inhibition of cell movement and proliferation

(2008) Yoshimi Takai et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY