Whole Genome Transcript Profiling of Drug Induced Steatosis in Rats Reveals a Gene Signature Predictive of Outcome

Repression of glucocorticoid-stimulated angiopoietin-like 4 gene transcription by insulin

(2014) Taiyi Kuo et al.   JOURNAL OF LIPID RESEARCH

Recent insights into the molecular pathophysiology of lipid droplet formation in hepatocytes

(2014) Nishika Sahini et al.   PROGRESS IN LIPID RESEARCH

Drug-Induced Hepatic Steatosis

(2014) Naga Chalasani et al.   SEMINARS IN LIVER DISEASE

The human liver fatty acid binding protein (FABP1) gene is activated by FOXA1 and PPARα; and repressed by C/EBPα: Implications in FABP1 down-regulation in nonalcoholic fatty liver disease

(2013) Carla Guzmán et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Incidence, Presentation, and Outcomes in Patients With Drug-Induced Liver Injury in the General Population of Iceland

(2013) Einar S. Björnsson et al.   GASTROENTEROLOGY

Docosahexaenoic Acid Attenuates Hepatic Inflammation, Oxidative Stress, and Fibrosis without Decreasing Hepatosteatosis in a Ldlr−/− Mouse Model of Western Diet-Induced Nonalcoholic Steatohepatitis

(2013) Christopher M. Depner et al.   JOURNAL OF NUTRITION

Methionine restriction prevents the progression of hepatic steatosis in leptin-deficient obese mice

(2013) Virginia L. Malloy et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

The biophysics and cell biology of lipid droplets

(2013) Abdou Rachid Thiam et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hepatic Methionine Homeostasis Is Conserved in C57BL/6N Mice on High-Fat Diet Despite Major Changes in Hepatic One-Carbon Metabolism

(2013) Christoph Dahlhoff et al.   PLoS One

Vitamin A status affects obesity development and hepatic expression of key genes for fuel metabolism in Zucker fatty rats

(2012) Yan Zhang et al.   Biochemistry and Cell Biology

Drug-induced Liver Steatosis and Phospholipidosis: Cell-Based Assays for Early Screening of Drug Candidates

(2012) M. Teresa Donato et al.   CURRENT DRUG METABOLISM

The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans

(2012) Fadila Benhamed et al.   JOURNAL OF CLINICAL INVESTIGATION

In vitro validation of drug-induced phospholipidosis

(2012) Sora Park et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Lycopene inhibits hepatic steatosis via microRNA-21-induced downregulation of fatty acid-binding protein 7 in mice fed a high-fat diet

(2012) Jiyun Ahn et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Palmitoleate Induces Hepatic Steatosis but Suppresses Liver Inflammatory Response in Mice

(2012) Xin Guo et al.   PLoS One

Optimization of the HepaRG cell model for drug metabolism and toxicity studies

(2012) Sébastien Anthérieu et al.   TOXICOLOGY IN VITRO

A Systems Biology Approach to Deciphering the Etiology of Steatosis Employing Patient-Derived Dermal Fibroblasts and iPS Cells

(2012) Justyna Jozefczuk et al.   Frontiers in Physiology

Growth Hormone-Dependent Pathogenesis of Human Hepatic Steatosis in a Novel Mouse Model Bearing a Human Hepatocyte-Repopulated Liver

(2011) Chise Tateno et al.   ENDOCRINOLOGY

Induction of vesicular steatosis by amiodarone and tetracycline is associated with up-regulation of lipogenic genes in heparg cells

(2011) Sébastien Anthérieu et al.   HEPATOLOGY

Inflammation-associated interleukin-6/signal transducer and activator of transcription 3 activation ameliorates alcoholic and nonalcoholic fatty liver diseases in interleukin-10-deficient mice

(2011) Andrew M. Miller et al.   HEPATOLOGY

Dietary cholesterol exacerbates hepatic steatosis and inflammation in obese LDL receptor-deficient mice

(2011) Savitha Subramanian et al.   JOURNAL OF LIPID RESEARCH

An endocrine perspective of nonalcoholic fatty liver disease (NAFLD)

(2011) Romina Lomonaco et al.   Therapeutic Advances in Endocrinology and Metabolism

Activation of the aryl hydrocarbon receptor induces hepatic steatosis via the upregulation of fatty acid transport

(2010) Yuki Kawano et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Protective Effects of Vitamin E Analogs against Carbon Tetrachloride-Induced Fatty Liver in Rats

(2010) Rieko Yachi et al.   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

Drug-induced toxicity on mitochondria and lipid metabolism: Mechanistic diversity and deleterious consequences for the liver

(2010) Karima Begriche et al.   JOURNAL OF HEPATOLOGY

Steatosis as a co-factor in chronic liver diseases

(2010) Marcello Persico   WORLD JOURNAL OF GASTROENTEROLOGY

Angiopoietin-like 4 (ANGPTL4, Fasting-induced Adipose Factor) Is a Direct Glucocorticoid Receptor Target and Participates in Glucocorticoid-regulated Triglyceride Metabolism

(2009) Suneil K. Koliwad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Japanese toxicogenomics project: Application of toxicogenomics

(2009) Takeki Uehara et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Differential pattern of lipid droplet-associated proteins andde novoperilipin expression in hepatocyte steatogenesis

(2008) Beate Katharina Straub et al.   HEPATOLOGY

Abrogation of hepatic ATP-citrate lyase protects against fatty liver and ameliorates hyperglycemia in leptin receptor-deficient mice

(2008) Qiong Wang et al.   HEPATOLOGY

Deletion of ELOVL5 leads to fatty liver through activation of SREBP-1c in mice

(2008) Young-Ah Moon et al.   JOURNAL OF LIPID RESEARCH

Molecular Mechanisms and Therapeutic Targets in Steatosis and Steatohepatitis

(2008) N. Anderson et al.   PHARMACOLOGICAL REVIEWS

Gene expression profiling in rat liver treated with compounds inducing phospholipidosis

(2008) M HIRODE et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

PTEN Down-Regulation by Unsaturated Fatty Acids Triggers Hepatic Steatosis via an NF-κBp65/mTOR-Dependent Mechanism

(2007) Manlio Vinciguerra et al.   GASTROENTEROLOGY