Formal Modelling of Toll like Receptor 4 and JAK/STAT Signalling Pathways: Insight into the Roles of SOCS-1, Interferon-β and Proinflammatory Cytokines in Sepsis

SOCS1 Regulates the IFN but Not NF B Pathway in TLR-Stimulated Human Monocytes and Macrophages

(2014) C. M. Prele et al.   JOURNAL OF IMMUNOLOGY

Modeling approaches for qualitative and semi-quantitative analysis of cellular signaling networks

(2013) Regina Samaga et al.   Cell Communication and Signaling

Immunosuppression in sepsis: a novel understanding of the disorder and a new therapeutic approach

(2013) Richard S Hotchkiss et al.   LANCET INFECTIOUS DISEASES

Sepsis: Multiple Abnormalities, Heterogeneous Responses, and Evolving Understanding

(2013) Kendra N. Iskander et al.   PHYSIOLOGICAL REVIEWS

A Reduction Method for Boolean Network Models Proven to Conserve Attractors

(2013) Assieh Saadatpour et al.   SIAM JOURNAL ON APPLIED DYNAMICAL SYSTEMS

Formal Modeling and Analysis of the MAL-Associated Biological Regulatory Network: Insight into Cerebral Malaria

(2012) Jamil Ahmad et al.   PLoS One

The Timing of IFNβ Production Affects Early Innate Responses to Listeria monocytogenes and Determines the Overall Outcome of Lethal Infection

(2012) Francesca Pontiroli et al.   PLoS One

Hospitalizations, costs, and outcomes of severe sepsis in the United States 2003 to 2007

(2011) Tara Lagu et al.   CRITICAL CARE MEDICINE

Toll-like Receptors and Their Crosstalk with Other Innate Receptors in Infection and Immunity

(2011) Taro Kawai et al.   IMMUNITY

Mixed antagonist response and sepsis severity-dependent dysbalance of pro- and anti-inflammatory responses at the onset of postoperative sepsis

(2011) Alexander R. Novotny et al.   IMMUNOBIOLOGY

The Search for Effective Therapy for Sepsis

(2011) Derek C. Angus   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

A dual negative regulation model of Toll-like receptor 4 signaling for endotoxin preconditioning in human endotoxemia

(2011) Qian Yang et al.   MATHEMATICAL BIOSCIENCES

Production of IFN-β during Listeria monocytogenes Infection Is Restricted to Monocyte/Macrophage Lineage

(2011) Evgenia Solodova et al.   PLoS One

The TRAF-associated protein TANK facilitates cross-talk within the I B kinase family during Toll-like receptor signaling

(2011) K. Clark et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Regulation and Function of NF-κB Transcription Factors in the Immune System

(2009) Sivakumar Vallabhapurapu et al.   Annual Review of Immunology

A TIR Domain Variant of MyD88 Adapter-like (Mal)/TIRAP Results in Loss of MyD88 Binding and Reduced TLR2/TLR4 Signaling

(2009) Kamalpreet Nagpal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Compensatory Anti-inflammatory Response Syndrome (CARS) in Critically Ill Patients

(2008) Nicholas S. Ward et al.   CLINICS IN CHEST MEDICINE

LPS/TLR4 signal transduction pathway

(2008) Yong-Chen Lu et al.   CYTOKINE

Role of Toll-like receptor responses for sepsis pathogenesis

(2007) Heike Weighardt et al.   IMMUNOBIOLOGY