Serum RANKL levels associate with anti- citrullinated protein antibodies in early untreated rheumatoid arthritis and are modulated following methotrexate

Overweight decreases the chance of achieving good response and low disease activity in early rheumatoid arthritis

(2014) Maria E C Sandberg et al.   ANNALS OF THE RHEUMATIC DISEASES

Bone loss before the clinical onset of rheumatoid arthritis in subjects with anticitrullinated protein antibodies

(2013) Arnd Kleyer et al.   ANNALS OF THE RHEUMATIC DISEASES

EULAR definition of erosive disease in light of the 2010 ACR/EULAR rheumatoid arthritis classification criteria

(2013) Désirée van der Heijde et al.   ANNALS OF THE RHEUMATIC DISEASES

Low-avidity anticitrullinated protein antibodies (ACPA) are associated with a higher rate of joint destruction in rheumatoid arthritis

(2013) Parawee Suwannalai et al.   ANNALS OF THE RHEUMATIC DISEASES

Environmental and genetic factors in the development of anticitrullinated protein antibodies (ACPAs) and ACPA-positive rheumatoid arthritis: an epidemiological investigation in twins

(2013) Aase Haj Hensvold et al.   ANNALS OF THE RHEUMATIC DISEASES

Biologic therapies and systemic bone loss in rheumatoid arthritis

(2013) Theodoros Dimitroulas et al.   AUTOIMMUNITY REVIEWS

The effect of targeted rheumatoid arthritis therapies on anti-citrullinated protein autoantibody levels and B cell responses

(2013) S. Modi et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Synovial membrane immunohistology in early-untreated rheumatoid arthritis reveals high expression of catabolic bone markers that is modulated by methotrexate

(2013) Shankar Revu et al.   ARTHRITIS RESEARCH & THERAPY

Genetic and environmental determinants for disease risk in subsets of rheumatoid arthritis defined by the anticitrullinated protein/peptide antibody fine specificity profile

(2012) Karin Lundberg et al.   ANNALS OF THE RHEUMATIC DISEASES

Induction of osteoclastogenesis and bone loss by human autoantibodies against citrullinated vimentin

(2012) Ulrike Harre et al.   JOURNAL OF CLINICAL INVESTIGATION

Bench to bedside: elucidation of the OPG–RANK–RANKL pathway and the development of denosumab

(2012) David L. Lacey et al.   NATURE REVIEWS DRUG DISCOVERY

New developments in osteoimmunology

(2012) Hiroshi Takayanagi   Nature Reviews Rheumatology

Bone erosion in rheumatoid arthritis: mechanisms, diagnosis and treatment

(2012) Georg Schett et al.   Nature Reviews Rheumatology

Low-dose prednisolone in early rheumatoid arthritis inhibits collagen type I degradation by matrix metalloproteinases as assessed by serum 1CTP--a possible mechanism for specific inhibition of radiological destruction

(2012) I.-L. Engvall et al.   RHEUMATOLOGY

Validation of a novel multibiomarker test to assess rheumatoid arthritis disease activity

(2012) Jeffrey R. Curtis et al.   ARTHRITIS CARE & RESEARCH

Rituximab abrogates joint destruction in rheumatoid arthritis by inhibiting osteoclastogenesis

(2011) Maria J H Boumans et al.   ANNALS OF THE RHEUMATIC DISEASES

Antibodies to citrullinated  -enolase peptide 1 and clinical and radiological outcomes in rheumatoid arthritis

(2011) B. A. Fisher et al.   ANNALS OF THE RHEUMATIC DISEASES

In early rheumatoid arthritis, patients with a good initial response to methotrexate have excellent 2-year clinical outcomes, but radiological progression is not fully prevented: data from the methotrexate responders population in the SWEFOT trial

(2011) Hamed Rezaei et al.   ANNALS OF THE RHEUMATIC DISEASES

Distinct ACPA fine specificities, formed under the influence of HLA shared epitope alleles, have no effect on radiographic joint damage in rheumatoid arthritis

(2011) H. U. Scherer et al.   ANNALS OF THE RHEUMATIC DISEASES

Baseline RANKL:OPG ratio and markers of bone and cartilage degradation predict annual radiological progression over 11 years in rheumatoid arthritis

(2010) L. H. D. van Tuyl et al.   ANNALS OF THE RHEUMATIC DISEASES

Bone metabolism is altered in preclinical rheumatoid arthritis

(2010) D. van Schaardenburg et al.   ANNALS OF THE RHEUMATIC DISEASES

The ACPA isotype profile reflects long-term radiographic progression in rheumatoid arthritis

(2010) D. van der Woude et al.   ANNALS OF THE RHEUMATIC DISEASES

Patients with early rheumatoid arthritis who smoke are less likely to respond to treatment with methotrexate and tumor necrosis factor inhibitors: Observations from the Epidemiological Investigation of Rheumatoid Arthritis and the Swedish Rheumatology Reg

(2010) Saedis Saevarsdottir et al.   ARTHRITIS AND RHEUMATISM

Levels of anti-citrullinated protein antibodies and IgM rheumatoid factor are not associated with outcome in early arthritis patients: a cohort study

(2010) Jennie Ursum et al.   ARTHRITIS RESEARCH & THERAPY

Cartilage and Bone Biomarkers in Rheumatoid Arthritis: Prediction of 10-year Radiographic Progression

(2009) S. W. SYVERSEN et al.   JOURNAL OF RHEUMATOLOGY

Specific interaction between genotype, smoking and autoimmunity to citrullinated α-enolase in the etiology of rheumatoid arthritis

(2009) Hiba Mahdi et al.   NATURE GENETICS

Osteoimmunology and the effects of the immune system on bone

(2009) Hiroshi Takayanagi   Nature Reviews Rheumatology

Synovial tissue rank ligand expression and radiographic progression in rheumatoid arthritis: observations from a proof-of-concept randomized clinical trial of cytokine blockade

(2009) Terence Rooney et al.   RHEUMATOLOGY INTERNATIONAL

Modulation of RANKL and osteoprotegerin expression in synovial tissue from patients with rheumatoid arthritis in response to disease‐modifying antirheumatic drug treatment and correlation with radiologic outcome

(2008) David Haynes et al.   ARTHRITIS AND RHEUMATISM

Antibodies to mutated citrullinated vimentin and disease activity score in early arthritis: a cohort study

(2008) Jennie Ursum et al.   ARTHRITIS RESEARCH & THERAPY