The Pore-Domain of TRPA1 Mediates the Inhibitory Effect of the Antagonist 6-Methyl-5-(2-(trifluoromethyl)phenyl)-1H-indazole

Directionality of Temperature Activation in Mouse TRPA1 Ion Channel Can Be Inverted by Single-Point Mutations in Ankyrin Repeat Six

(2014) Sairam Jabba et al.   NEURON

Warmth Suppresses and Desensitizes Damage-Sensing Ion Channel TRPA1

(2012) Sen Wang et al.   Molecular Pain

The Dynamic TRPA1 Channel: A Suitable Pharmacological Pain Target?

(2011) Sheldon R. Garrison et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Cytoplasmic ankyrin repeats of transient receptor potential A1 (TRPA1) dictate sensitivity to thermal and chemical stimuli

(2011) J. F. Cordero-Morales et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Met268Pro Mutation of Mouse TRPA1 Changes the Effect of Caffeine from Activation to Suppression

(2010) Katsuhiro Nagatomo et al.   BIOPHYSICAL JOURNAL

TRPA1: the species difference: Figure 1.

(2009) Jun Chen et al.   JOURNAL OF GENERAL PHYSIOLOGY

Zinc activates damage-sensing TRPA1 ion channels

(2009) Hongzhen Hu et al.   Nature Chemical Biology

TRPA1 acts as a cold sensor in vitro and in vivo

(2009) Y. Karashima et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of Transmembrane Domain 5 as a Critical Molecular Determinant of Menthol Sensitivity in Mammalian TRPA1 Channels

(2008) B. Xiao et al.   JOURNAL OF NEUROSCIENCE

Molecular Determinants of Species-Specific Activation or Blockade of TRPA1 Channels

(2008) J. Chen et al.   JOURNAL OF NEUROSCIENCE

Pore region of TRPV3 ion channel is specifically required for heat activation

(2008) Jörg Grandl et al.   NATURE NEUROSCIENCE

Transient receptor potential channels: targeting pain at the source

(2008) Ardem Patapoutian et al.   NATURE REVIEWS DRUG DISCOVERY