Interleukin-6-dependent influence of nociceptive sensory neurons on antigen-induced arthritis

H2S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO–TRPA1–CGRP signalling pathway

(2015) Mirjam Eberhardt et al.   Nature Communications

Deletion of Interleukin-6 Signal Transducer gp130 in Small Sensory Neurons Attenuates Mechanonociception and Down-Regulates TRPA1 Expression

(2014) P. Malsch et al.   JOURNAL OF NEUROSCIENCE

IL-6 biology: implications for clinical targeting in rheumatic disease

(2014) Leonard H. Calabrese et al.   Nature Reviews Rheumatology

Reduced excitability of gp130-deficient nociceptors is associated with increased voltage-gated potassium currents and Kcna4 channel upregulation

(2014) Michiel Langeslag et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Peripheral Calcitonin Gene-Related Peptide Receptor Activation and Mechanical Sensitization of the Joint in Rat Models of Osteoarthritis Pain

(2014) Craig M. Bullock et al.   Arthritis & Rheumatology

Increased Th17 Cell Frequency and Poor Clinical Outcome in Rheumatoid Arthritis Are Associated With a Genetic Variant in theIL4RGene, rs1805010

(2014) Jan Leipe et al.   Arthritis & Rheumatology

Exacerbated inflammatory arthritis in response to hyperactive gp130 signalling is independent of IL-17A

(2013) G W Jones et al.   ANNALS OF THE RHEUMATIC DISEASES

The innervation of synovium of human osteoarthritic joints in comparison with normal rat and sheep synovium

(2013) A. Eitner et al.   OSTEOARTHRITIS AND CARTILAGE

Spinal interleukin-6 is an amplifier of arthritic pain in the rat

(2012) Enrique Vazquez et al.   ARTHRITIS AND RHEUMATISM

Pain-like behaviour and spinal changes in the monosodium iodoacetate model of osteoarthritis in C57Bl/6 mice

(2012) A. C. Ogbonna et al.   EUROPEAN JOURNAL OF PAIN

Role of peripheral nerve fibres in acute and chronic inflammation in arthritis

(2012) Georg Pongratz et al.   Nature Reviews Rheumatology

The anti-inflammatory effects of sympathectomy in murine antigen-induced arthritis are associated with a reduction of Th1 and Th17 responses

(2011) Matthias Ebbinghaus et al.   ANNALS OF THE RHEUMATIC DISEASES

Genetic Evidence for an Essential Role of Neuronally Expressed IL-6 Signal Transducer gp130 in the Induction and Maintenance of Experimentally Induced Mechanical Hypersensitivity in vivo and in vitro

(2011) Serena Quarta et al.   Molecular Pain

Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages

(2011) Wei Liao et al.   NATURE IMMUNOLOGY

Opposing regulation of the locus encoding IL-17 through direct, reciprocal actions of STAT3 and STAT5

(2011) Xiang-Ping Yang et al.   NATURE IMMUNOLOGY

Evaluation of long-term antinociceptive properties of stabilized hyaluronic acid preparation (NASHA) in an animal model of repetitive joint pain

(2011) Michael Boettger et al.   ARTHRITIS RESEARCH & THERAPY

Reversal of pancreatitis-induced pain by an orally available, small molecule interleukin-6 receptor antagonist

(2010) Marina Vardanyan et al.   PAIN

Inhibition of interleukin-6 receptor directly blocks osteoclast formation in vitro and in vivo

(2009) Roland Axmann et al.   ARTHRITIS AND RHEUMATISM

Interleukin-6 as a key player in systemic inflammation and joint destruction

(2009) J.E. Fonseca et al.   AUTOIMMUNITY REVIEWS

A Key Role for gp130 Expressed on Peripheral Sensory Nerves in Pathological Pain

(2009) M. Andratsch et al.   JOURNAL OF NEUROSCIENCE

Interleukin-17 and Type 17 Helper T Cells

(2009) Pierre Miossec et al.   NEW ENGLAND JOURNAL OF MEDICINE

Interleukin-6 blockade suppresses autoimmune arthritis in mice by the inhibition of inflammatory Th17 responses

(2008) Minoru Fujimoto et al.   ARTHRITIS AND RHEUMATISM

Antinociceptive effects of tumor necrosis factor α neutralization in a rat model of antigen-induced arthritis: Evidence of a neuronal target

(2008) Michael K. Boettger et al.   ARTHRITIS AND RHEUMATISM