Alteration in Mir-21/PTEN Expression Modulates Gefitinib Resistance in Non-Small Cell Lung Cancer

Inherited Variation in miR-290 Expression Suppresses Breast Cancer Progression by Targeting the Metastasis Susceptibility Gene Arid4b

(2013) N. Goldberger et al.   CANCER RESEARCH

miR-124 Inhibits STAT3 Signaling to Enhance T Cell–Mediated Immune Clearance of Glioma

(2013) Jun Wei et al.   CANCER RESEARCH

Targeting miR-21 Inhibits In Vitro and In Vivo Multiple Myeloma Cell Growth

(2013) E. Leone et al.   CLINICAL CANCER RESEARCH

Serum miR-21 as a Diagnostic and Prognostic Biomarker in Colorectal Cancer

(2013) Yuji Toiyama et al.   JNCI-Journal of the National Cancer Institute

MiR-21 overexpression is associated with acquired resistance of EGFR-TKI in non-small cell lung cancer

(2013) Bing Li et al.   LUNG CANCER

miR-21 confers cisplatin resistance in gastric cancer cells by regulating PTEN

(2013) Shou-mei Yang et al.   TOXICOLOGY

MicroRNA-214 Regulates the Acquired Resistance to Gefitinib via the PTEN/AKT Pathway in EGFR-mutant Cell Lines

(2012) Yong-Sheng Wang et al.   Asian Pacific Journal of Cancer Prevention

Reduced miR-31 and let-7 maintain the balance between differentiation and quiescence in lung cancer stem-like side population cells

(2012) Shen Hua et al.   BIOMEDICINE & PHARMACOTHERAPY

MiRNA-21

(2012) Wen Gao et al.   CANCER BIOLOGY & THERAPY

Met Kinase Inhibitor E7050 Reverses Three Different Mechanisms of Hepatocyte Growth Factor-Induced Tyrosine Kinase Inhibitor Resistance in EGFR Mutant Lung Cancer

(2012) W. Wang et al.   CLINICAL CANCER RESEARCH

High expression of miR-21 and miR-155 predicts recurrence and unfavourable survival in non-small cell lung cancer

(2012) Miaomiao Yang et al.   EUROPEAN JOURNAL OF CANCER

MicroRNA-21 regulates the sensitivity of diffuse large B-cell lymphoma cells to the CHOP chemotherapy regimen

(2012) Haitao Bai et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

MicroRNA-21 gene and cancer

(2012) Yong Huang et al.   MEDICAL ONCOLOGY

MicroRNA-21 (miR-21) expression promotes growth, metastasis, and chemo- or radioresistance in non-small cell lung cancer cells by targeting PTEN

(2012) Zhi-Li Liu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The Association of MicroRNA Expression with Prognosis and Progression in Early-Stage, Non-Small Cell Lung Adenocarcinoma: A Retrospective Analysis of Three Cohorts

(2011) M. Saito et al.   CLINICAL CANCER RESEARCH

Transient PI3K Inhibition Induces Apoptosis and Overcomes HGF-Mediated Resistance to EGFR-TKIs in EGFR Mutant Lung Cancer

(2011) I. S. Donev et al.   CLINICAL CANCER RESEARCH

MicroRNA Molecular Profiles Associated with Diagnosis, Clinicopathologic Criteria, and Overall Survival in Patients with Resectable Pancreatic Ductal Adenocarcinoma

(2011) N. B. Jamieson et al.   CLINICAL CANCER RESEARCH

Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study

(2011) Caicun Zhou et al.   LANCET ONCOLOGY

Cadmium Increases HIF-1 and VEGF Expression through ROS, ERK, and AKT Signaling Pathways and Induces Malignant Transformation of Human Bronchial Epithelial Cells

(2011) Yi Jing et al.   TOXICOLOGICAL SCIENCES

Involvement of microRNA-21 in mediating chemo-resistance to docetaxel in androgen-independent prostate cancer PC3 cells

(2010) Guo-hai Shi et al.   ACTA PHARMACOLOGICA SINICA

Elevated IGFIR expression regulating VEGF and VEGF-C predicts lymph node metastasis in human colorectal cancer

(2010) Chunhui Zhang et al.   BMC CANCER

MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity

(2010) Lei Shi et al.   BRAIN RESEARCH

MicroRNA-21 in Pancreatic Cancer: Correlation with Clinical Outcome and Pharmacologic Aspects Underlying Its Role in the Modulation of Gemcitabine Activity

(2010) Elisa Giovannetti et al.   CANCER RESEARCH

miR-181b modulates multidrug resistance by targeting BCL2 in human cancer cell lines

(2010) Wei Zhu et al.   INTERNATIONAL JOURNAL OF CANCER

Gefitinib or Chemotherapy for Non–Small-Cell Lung Cancer with Mutated EGFR

(2010) Makoto Maemondo et al.   NEW ENGLAND JOURNAL OF MEDICINE

MicroRNA-21 induces resistance to 5-fluorouracil by down-regulating human DNA MutS homolog 2 (hMSH2)

(2010) N. Valeri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Combined tamoxifen and gefitinib in non-small cell lung cancer shows antiproliferative effects

(2009) Hua Shen et al.   BIOMEDICINE & PHARMACOTHERAPY

Gefitinib versus cisplatin plus docetaxel in patients with non-small-cell lung cancer harbouring mutations of the epidermal growth factor receptor (WJTOG3405): an open label, randomised phase 3 trial

(2009) Tetsuya Mitsudomi et al.   LANCET ONCOLOGY

Gefitinib or Carboplatin–Paclitaxel in Pulmonary Adenocarcinoma

(2009) Tony S. Mok et al.   NEW ENGLAND JOURNAL OF MEDICINE

A PCR-based platform for microRNA expression profiling studies

(2009) X. Wang   RNA

MicroRNA Expression Profiles Associated With Prognosis and Therapeutic Outcome in Colon Adenocarcinoma

(2008) Aaron J. Schetter et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Molecular Characteristics of Bronchioloalveolar Carcinoma and Adenocarcinoma, Bronchioloalveolar Carcinoma Subtype, Predict Response to Erlotinib

(2008) Vincent A. Miller et al.   JOURNAL OF CLINICAL ONCOLOGY

Phase III Study Comparing Cisplatin Plus Gemcitabine With Cisplatin Plus Pemetrexed in Chemotherapy-Naive Patients With Advanced-Stage Non–Small-Cell Lung Cancer

(2008) Giorgio Vittorio Scagliotti et al.   JOURNAL OF CLINICAL ONCOLOGY

MicroRNAs modulate the chemosensitivity of tumor cells

(2008) P. E. Blower et al.   MOLECULAR CANCER THERAPEUTICS