A subset of patients with systemic lupus erythematosus fails to degrade DNA from multiple clinically relevant sources

Impaired DNase1-mediated degradation of neutrophil extracellular traps is associated with acute thrombotic microangiopathies

(2015) M. Jiménez-Alcázar et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Serum-dependent processing of late apoptotic cells for enhanced efferocytosis

(2014) Y Y Liang et al.   Cell Death & Disease

Oxidative Damage of DNA Confers Resistance to Cytosolic Nuclease TREX1 Degradation and Potentiates STING-Dependent Immune Sensing

(2013) Nadine Gehrke et al.   IMMUNITY

Macrophage Clearance of Neutrophil Extracellular Traps Is a Silent Process

(2013) C. Farrera et al.   JOURNAL OF IMMUNOLOGY

DNase γ Is the Effector Endonuclease for Internucleosomal DNA Fragmentation in Necrosis

(2013) Ryushin Mizuta et al.   PLoS One

Degradation of neutrophil extracellular traps co-varies with disease activity in patients with systemic lupus erythematosus

(2013) Jonatan Leffler et al.   ARTHRITIS RESEARCH & THERAPY

Cooperation of Factor VII-Activating Protease and Serum DNase I in the Release of Nucleosomes From Necrotic Cells

(2013) Femke Stephan et al.   Arthritis & Rheumatology

Serum DNase I activity in systemic lupus erythematosus: correlation with immunoserological markers, the disease activity and organ involvement

(2012) Dusan Skiljevic et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Lupus neutrophils

(2012) Jason S. Knight et al.   CURRENT OPINION IN RHEUMATOLOGY

Neutrophil Extracellular Traps That Are Not Degraded in Systemic Lupus Erythematosus Activate Complement Exacerbating the Disease

(2012) J. Leffler et al.   JOURNAL OF IMMUNOLOGY

Caspase-activated DNase is required for maintenance of tolerance to lupus nuclear autoantigens

(2011) Neelakshi R. Jog et al.   ARTHRITIS AND RHEUMATISM

Neutrophils Activate Plasmacytoid Dendritic Cells by Releasing Self-DNA-Peptide Complexes in Systemic Lupus Erythematosus

(2011) R. Lande et al.   Science Translational Medicine

Renal Dnase1 Enzyme Activity and Protein Expression Is Selectively Shut Down in Murine and Human Membranoproliferative Lupus Nephritis

(2010) Svetlana N. Zykova et al.   PLoS One

Impairment of neutrophil extracellular trap degradation is associated with lupus nephritis

(2010) A. Hakkim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anti-dsDNA Antibodies Promote Initiation, and Acquired Loss of Renal Dnase1 Promotes Progression of Lupus Nephritis in Autoimmune (NZBxNZW)F1 Mice

(2009) Kristin Fenton et al.   PLoS One

DNase1 activity in systemic lupus erythematosus patients with and without nephropathy

(2009) Fernando Martinez-Valle et al.   RHEUMATOLOGY INTERNATIONAL

Trex1 Prevents Cell-Intrinsic Initiation of Autoimmunity

(2008) Daniel B. Stetson et al.   CELL