Directed Differentiation of Patient-Specific Induced Pluripotent Stem Cells Identifies the Transcriptional Repression and Epigenetic Modification of NKX2-5, HAND1, and NOTCH1 in Hypoplastic Left Heart Syndrome

An Induced Pluripotent Stem Cell Model of Hypoplastic Left Heart Syndrome (HLHS) Reveals Multiple Expression and Functional Differences in HLHS-Derived Cardiac Myocytes

(2014) Yan Jiang et al.   Stem Cells Translational Medicine

Epigenetic Signature of Early Cardiac Regulatory Genes in Native Human Adipose-Derived Stem Cells

(2013) Alice Pasini et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy

(2013) Guillermo Luxán et al.   NATURE MEDICINE

Coordinating Tissue Interactions: Notch Signaling in Cardiac Development and Disease

(2012) José Luis de la Pompa et al.   DEVELOPMENTAL CELL

Interleukin-1β and transforming growth factor-β cooperate to induce neurosphere formation and increase tumorigenicity of adherent LN-229 glioma cells

(2012) Lei Wang et al.   Stem Cell Research & Therapy

Mechanisms of T-box gene function in the developing heart

(2011) F. Greulich et al.   CARDIOVASCULAR RESEARCH

Derivation of Human Induced Pluripotent Stem Cells for Cardiovascular Disease Modeling

(2011) Kamileh Narsinh et al.   CIRCULATION RESEARCH

Left Ventricular Hypoplasia

(2011) Edward J. Hickey et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Hand2 function in second heart field progenitors is essential for cardiogenesis

(2010) Takatoshi Tsuchihashi et al.   DEVELOPMENTAL BIOLOGY

Promoter DNA Methylation Patterns of Differentiated Cells Are Largely Programmed at the Progenitor Stage

(2010) Anita L. Sørensen et al.   MOLECULAR BIOLOGY OF THE CELL

Cardiac Development and Implications for Heart Disease

(2010) Jonathan A. Epstein   NEW ENGLAND JOURNAL OF MEDICINE

Telomerase-immortalized human mammary stem/progenitor cells with ability to self-renew and differentiate

(2010) X. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Signaling Pathways Controlling Second Heart Field Development

(2009) Francesca Rochais et al.   CIRCULATION RESEARCH

ABCB1 is predominantly expressed in human fetal neural stem/progenitor cells at an early development stage

(2009) Atsuyo Yamamoto et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The Effect of Age, Diagnosis, and Previous Surgery in Children and Adults Undergoing Heart Transplantation for Congenital Heart Disease

(2009) Jacqueline M. Lamour et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Hypoplastic Left Heart Syndrome Links to Chromosomes 10q and 6q and Is Genetically Related to Bicuspid Aortic Valve

(2009) Robert B. Hinton et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Hypoplastic left heart syndrome

(2009) David J Barron et al.   LANCET

Nongenetic method for purifying stem cell–derived cardiomyocytes

(2009) Fumiyuki Hattori et al.   NATURE METHODS

A loss-of-function mutation in the binding domain of HAND1 predicts hypoplasia of the human hearts

(2008) S. M. Reamon-Buettner et al.   HUMAN MOLECULAR GENETICS

NOTCH1 mutations in individuals with left ventricular outflow tract malformations reduce ligand-induced signaling

(2008) K. L. McBride et al.   HUMAN MOLECULAR GENETICS

Controlled Delivery of Basic Fibroblast Growth Factor Promotes Human Cardiosphere-Derived Cell Engraftment to Enhance Cardiac Repair for Chronic Myocardial Infarction

(2008) Naofumi Takehara et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

The developmental genetics of congenital heart disease

(2008) Benoit G. Bruneau   NATURE

Generation of human-induced pluripotent stem cells

(2008) In-Hyun Park et al.   Nature Protocols

Notch1 regulates the fate of cardiac progenitor cells

(2008) A. Boni et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA