Macrophage-Activating Lipopeptide-2 Requires Mal and PI3K for Efficient Induction of Heme Oxygenase-1

Lipoteichoic Acid Induces HO-1 Expression via the TLR2/MyD88/c-Src/NADPH Oxidase Pathway and Nrf2 in Human Tracheal Smooth Muscle Cells

(2014) I.-T. Lee et al.   JOURNAL OF IMMUNOLOGY

Lipopolysaccharide-Induced Expression of NAD(P)H:Quinone Oxidoreductase 1 and Heme Oxygenase-1 Protects against Excessive Inflammatory Responses in Human Monocytes

(2014) S. A. Rushworth et al.   JOURNAL OF IMMUNOLOGY

Mycoplasma fermentans MALP-2 Induces Heme Oxygenase-1 Expression via Mitogen-Activated Protein Kinases and Nrf2 Pathways To Modulate Cyclooxygenase 2 Expression in Human Monocytes

(2013) Xiaohua Ma et al.   Clinical and Vaccine Immunology

Modulation of IL-8 Boosted by Mycoplasma pneumoniae lysate in Human Airway Epithelial Cells

(2013) Kyung Eun Lee et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Mycoplasma genitalium Infection Activates Cellular Host Defense and Inflammation Pathways in a 3-Dimensional Human Endocervical Epithelial Cell Model

(2013) Chris L. McGowin et al.   JOURNAL OF INFECTIOUS DISEASES

Mycoplasmas and their host: emerging and re-emerging minimal pathogens

(2013) Christine Citti et al.   TRENDS IN MICROBIOLOGY

Persistent Mycoplasma genitalium Infection of Human Endocervical Epithelial Cells Elicits Chronic Inflammatory Cytokine Secretion

(2012) Chris L. McGowin et al.   INFECTION AND IMMUNITY

Tyrosine Kinase Btk Is Required for NK Cell Activation

(2012) Yan Bao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased Pro-inflammatory Cytokine Production After Lipopolysaccharide Stimulation in Patients with X-linked Agammaglobulinemia

(2012) María Edith González-Serrano et al.   JOURNAL OF CLINICAL IMMUNOLOGY

SHP-1 As a Critical Regulator of Mycoplasma pneumoniae-Induced Inflammation in Human Asthmatic Airway Epithelial Cells

(2012) Y. Wang et al.   JOURNAL OF IMMUNOLOGY

Molecular Methods for the Detection of Mycoplasma and Ureaplasma Infections in Humans

(2012) Ken B. Waites et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

The Role of Src Kinase in Macrophage-Mediated Inflammatory Responses

(2012) Se Eun Byeon et al.   MEDIATORS OF INFLAMMATION

The kinase Btk negatively regulates the production of reactive oxygen species and stimulation-induced apoptosis in human neutrophils

(2012) Fumiko Honda et al.   NATURE IMMUNOLOGY

Mycoplasma genitalium: from Chrysalis to Multicolored Butterfly

(2011) D. Taylor-Robinson et al.   CLINICAL MICROBIOLOGY REVIEWS

4-Ketopinoresinol, a novel naturally occurring ARE activator, induces the Nrf2/HO-1 axis and protects against oxidative stress-induced cell injury via activation of PI3K/AKT signaling

(2011) Huang-Hui Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

A Novel Role for Bruton's Tyrosine Kinase in Hepatocyte Growth Factor-mediated Immunoregulation of Dendritic Cells

(2011) Eshu Singhal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Notch Signal Suppresses Toll-like Receptor-triggered Inflammatory Responses in Macrophages by Inhibiting Extracellular Signal-regulated Kinase 1/2-mediated Nuclear Factor κB Activation

(2011) Qinghua Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pulmonary Surfactant Phosphatidylglycerol InhibitsMycoplasma pneumoniae-stimulated Eicosanoid Production from Human and Mouse Macrophages

(2011) Pitchaimani Kandasamy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mal Mediates TLR-Induced Activation of CREB and Expression of IL-10

(2011) M. Mellett et al.   JOURNAL OF IMMUNOLOGY

TNF Mediates the Sustained Activation of Nrf2 in Human Monocytes

(2011) S. A. Rushworth et al.   JOURNAL OF IMMUNOLOGY

Bruton's Tyrosine Kinase Is Required for TLR-Dependent Heme Oxygenase-1 Gene Activation via Nrf2 in Macrophages

(2011) V. Vijayan et al.   JOURNAL OF IMMUNOLOGY

Potential Role of Mycoplasma hominis in Interleukin (IL)–17–Producing CD4+ T-Cell Generation Via Induction of IL-23 Secretion by Human Dendritic Cells

(2011) Marie-Elise Truchetet et al.   JOURNAL OF INFECTIOUS DISEASES

The orphan nuclear receptor SHP acts as a negative regulator in inflammatory signaling triggered by Toll-like receptors

(2011) Jae-Min Yuk et al.   NATURE IMMUNOLOGY

Intracellular MHC class II molecules promote TLR-triggered innate immune responses by maintaining activation of the kinase Btk

(2011) Xingguang Liu et al.   NATURE IMMUNOLOGY

The proteome of Mycoplasma pneumoniae, a supposedly “simple” cell

(2011) Ina Catrein et al.   PROTEOMICS

Heme oxygenase-1 signals are involved in preferential inhibition of pro-inflammatory cytokine release by surfactin in cells activated with Porphyromonas gingivalis lipopolysaccharide

(2010) Sun Young Park et al.   CHEMICO-BIOLOGICAL INTERACTIONS

IRAK1 and IRAK4 Promote Phosphorylation, Ubiquitination, and Degradation of MyD88 Adaptor-like (Mal)

(2010) Aisling Dunne et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caspase-1 targets the TLR adaptor Mal at a crucial TIR-domain interaction site

(2010) P. Ulrichts et al.   JOURNAL OF CELL SCIENCE

TLR-signaling Networks

(2010) J. Brown et al.   JOURNAL OF DENTAL RESEARCH

Small molecule inhibition of phosphatidylinositol-3,4,5-triphosphate (PIP3) binding to pleckstrin homology domains

(2010) B. Miao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple protein kinase pathways mediate amplified IL-6 release by human lung fibroblasts co-exposed to nickel and TLR-2 agonist, MALP-2

(2010) Fei Gao et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Overexpression of HO-1 Protects against TNF-α-Mediated Airway Inflammation by Down-Regulation of TNFR1-Dependent Oxidative Stress

(2009) I-Ta Lee et al.   AMERICAN JOURNAL OF PATHOLOGY

Mal connects TLR2 to PI3Kinase activation and phagocyte polarization

(2009) S Santos-Sierra et al.   EMBO JOURNAL

MyD88 Adapter-like (Mal)/TIRAP Interaction with TRAF6 Is Critical for TLR2- and TLR4-mediated NF-κB Proinflammatory Responses

(2009) Brett Verstak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MyD88 Adaptor-Like Is Not Essential for TLR2 Signaling and Inhibits Signaling by TLR3

(2009) E. F. Kenny et al.   JOURNAL OF IMMUNOLOGY

When Signaling Pathways Collide: Positive and Negative Regulation of Toll-like Receptor Signal Transduction

(2008) Luke A.J. O'Neill   IMMUNITY