Cytochrome P450 Monooxygenase CYP53 Family in Fungi: Comparative Structural and Evolutionary Analysis and Its Role as a Common Alternative Anti-Fungal Drug Target

Genome-wide identification, annotation and characterization of novel thermostable cytochrome P450 monooxygenases from the thermophilic biomass-degrading fungi Thielavia terrestris and Myceliophthora thermophila

(2014) Khajamohiddin Syed et al.   Genes & Genomics

Systematic Identification and Evolutionary Analysis of Catalytically Versatile Cytochrome P450 Monooxygenase Families Enriched in Model Basidiomycete Fungi

(2014) Khajamohiddin Syed et al.   PLoS One

Comparative Analysis of P450 Signature Motifs EXXR and CXG in the Large and Diverse Kingdom of Fungi: Identification of Evolutionarily Conserved Amino Acid Patterns Characteristic of P450 Family

(2014) Khajamohiddin Syed et al.   PLoS One

Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer

(2014) B. C. Monk et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CYP63A2, a Catalytically Versatile Fungal P450 Monooxygenase Capable of Oxidizing Higher-Molecular-Weight Polycyclic Aromatic Hydrocarbons, Alkylphenols, and Alkanes

(2013) Khajamohiddin Syed et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Antifungal activity of cinnamic acid derivatives involves inhibition of benzoate 4-hydroxylase (CYP53)

(2013) B. Korošec et al.   JOURNAL OF APPLIED MICROBIOLOGY

Genomewide annotation and comparative genomics of cytochrome P450 monooxygenases (P450s) in the polypore species Bjerkandera adusta, Ganoderma sp. and Phlebia brevispora

(2013) Khajamohiddin Syed et al.   MYCOLOGIA

Evaluation of structural features in fungal cytochromes P450 predicted to rule catalytic diversification

(2012) Peter Hlavica   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Comparative genomics of the white-rot fungi, Phanerochaete carnosa and P. chrysosporium, to elucidate the genetic basis of the distinct wood types they colonize

(2012) Hitoshi Suzuki et al.   BMC GENOMICS

Systematic and searchable classification of cytochrome P450 proteins encoded by fungal and oomycete genomes

(2012) Venkatesh Moktali et al.   BMC GENOMICS

P450 monooxygenases (P450ome) of the model white rot fungusPhanerochaete chrysosporium

(2012) Khajamohiddin Syed et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Spatial mapping of extracellular oxidant production by a white rot basidiomycete on wood reveals details of ligninolytic mechanism

(2012) Christopher G. Hunt et al.   ENVIRONMENTAL MICROBIOLOGY

Comparative genomics of Ceriporiopsis subvermispora and Phanerochaete chrysosporium provide insight into selective ligninolysis

(2012) E. Fernandez-Fueyo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Paleozoic Origin of Enzymatic Lignin Decomposition Reconstructed from 31 Fungal Genomes

(2012) D. Floudas et al.   SCIENCE

Genome sequence of the model medicinal mushroom Ganoderma lucidum

(2012) Shilin Chen et al.   Nature Communications

Molecular identification and functional characterization of cytochrome P450 monooxygenases from the brown-rot basidiomycete Postia placenta

(2011) Masamichi Ide et al.   ARCHIVES OF MICROBIOLOGY

Characterization of model compounds of processed lignin and the lignome by using atmospheric pressure ionization tandem mass spectrometry

(2011) Laura J. Haupert et al.   FUEL

MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods

(2011) K. Tamura et al.   MOLECULAR BIOLOGY AND EVOLUTION

Cytochrome P450 enzymes in the fungal kingdom

(2010) B. Črešnar et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Toward the estimation of the absolute quality of individual protein structure models

(2010) Pascal Benkert et al.   BIOINFORMATICS

3DLigandSite: predicting ligand-binding sites using similar structures

(2010) Mark N. Wass et al.   NUCLEIC ACIDS RESEARCH

Antifungals: Need to search for a new molecular target

(2009) AT Sangamwar et al.   INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES

CYP53A15 of Cochliobolus lunatus, a Target for Natural Antifungal Compounds†

(2008) Barbara Podobnik et al.   JOURNAL OF MEDICINAL CHEMISTRY

PROMALS3D: a tool for multiple protein sequence and structure alignments

(2008) Jimin Pei et al.   NUCLEIC ACIDS RESEARCH

High diversity and complex evolution of fungal cytochrome P450 reductase: Cytochrome P450 systems

(2007) Ljerka Lah et al.   FUNGAL GENETICS AND BIOLOGY

Distance-scaled, finite ideal-gas reference state improves structure-derived potentials of mean force for structure selection and stability prediction

(2002) Hongyi Zhou et al.   PROTEIN SCIENCE