The Protective Role of Fucosylated Chondroitin Sulfate, a Distinct Glycosaminoglycan, in a Murine Model of Streptozotocin-Induced Diabetic Nephropathy

Modulation of heparan sulfate in the glomerular endothelial glycocalyx decreases leukocyte influx during experimental glomerulonephritis

(2014) Angelique LWMM Rops et al.   KIDNEY INTERNATIONAL

Reduced Sulfation of Chondroitin Sulfate but Not Heparan Sulfate in Kidneys of Diabetic db/db Mice

(2013) Trine M. Reine et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

The role of heparanase and the endothelial glycocalyx in the development of proteinuria

(2013) Marjolein Garsen et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Sulodexide Decreases Albuminuria and Regulates Matrix Protein Accumulation in C57BL/6 Mice with Streptozotocin-Induced Type I Diabetic Nephropathy

(2013) Susan Yung et al.   PLoS One

Alteration of endothelial proteoglycan and heparanase gene expression by high glucose, insulin and heparin

(2013) J. Han et al.   VASCULAR PHARMACOLOGY

Discounting the Efficacy of Sulodexide in Diabetic Nephropathy Is Premature

(2012) Giovanni Gambaro   AMERICAN JOURNAL OF KIDNEY DISEASES

A new mechanism of action of sulodexide in diabetic nephropathy: inhibits heparanase-1 and prevents FGF-2-induced renal epithelial-mesenchymal transition

(2012) Valentina Masola et al.   Journal of Translational Medicine

Podocyte detachment and reduced glomerular capillary endothelial fenestration promote kidney disease in type 2 diabetic nephropathy

(2012) E. Jennifer Weil et al.   KIDNEY INTERNATIONAL

Sulodexide for Kidney Protection in Type 2 Diabetes Patients With Microalbuminuria: A Randomized Controlled Trial

(2011) Edmund J. Lewis et al.   AMERICAN JOURNAL OF KIDNEY DISEASES

Changes in cardiac heparan sulfate proteoglycan expression and streptozotocin-induced diastolic dysfunction in rats

(2011) Célia MC Strunz et al.   Cardiovascular Diabetology

Heparanase Is Essential for the Development of Diabetic Nephropathy in Mice

(2011) N. Gil et al.   DIABETES

Diabetes results in structural alteration of chondroitin sulfate/dermatan sulfate in the rat kidney: effects on the binding to extracellular matrix components

(2011) D. Joladarashi et al.   GLYCOBIOLOGY

Inhibitory effects of glycosaminoglycans on basal and stimulated transforming growth factor- 1 expression in mesangial cells: biochemical and structural considerations

(2011) M. Bacilieri et al.   GLYCOBIOLOGY

Sulodexide Fails to Demonstrate Renoprotection in Overt Type 2 Diabetic Nephropathy

(2011) D. K. Packham et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Urinary heparanase activity in patients with Type 1 and Type 2 diabetes

(2011) Angelique L.W.M.M. Rops et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Heparanase Levels Are Elevated in the Urine and Plasma of Type 2 Diabetes Patients and Associate with Blood Glucose Levels

(2011) Itay Shafat et al.   PLoS One

Diabetic kidney disease: act now or pay later

(2010) R. C. Atkins et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Glomerular filtration is normal in the absence of both agrin and perlecan–heparan sulfate from the glomerular basement membrane

(2009) Seth Goldberg et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Regulation of glomerular heparanase expression by aldosterone, angiotensin II and reactive oxygen species

(2009) M. J. van den Hoven et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Loss of heparan sulfate glycosaminoglycan assembly in podocytes does not lead to proteinuria

(2008) Shoujun Chen et al.   KIDNEY INTERNATIONAL

Proteinuria in diabetic kidney disease: A mechanistic viewpoint

(2008) J.A. Jefferson et al.   KIDNEY INTERNATIONAL

Properties of the Glomerular Barrier and Mechanisms of Proteinuria

(2008) Börje Haraldsson et al.   PHYSIOLOGICAL REVIEWS

Reduction of anionic sites in the glomerular basement membrane by heparanase does not lead to proteinuria

(2007) M.J. van den Hoven et al.   KIDNEY INTERNATIONAL