Accurate Identification of ALK Positive Lung Carcinoma Patients: Novel FDA-Cleared Automated Fluorescence In Situ Hybridization Scanning System and Ultrasensitive Immunohistochemistry
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Accurate Identification of ALK Positive Lung Carcinoma Patients: Novel FDA-Cleared Automated Fluorescence In Situ Hybridization Scanning System and Ultrasensitive Immunohistochemistry
Authors
Keywords
Immunohistochemistry techniques, Fluorescent in situ hybridization, Non-small cell lung cancer, Cytoplasmic staining, Cell staining, Carcinomas, Histology, Lung and intrathoracic tumors
Journal
PLoS One
Volume 9, Issue 9, Pages e107200
Publisher
Public Library of Science (PLoS)
Online
2014-09-24
DOI
10.1371/journal.pone.0107200
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Immunohistochemistry, Fluorescence in Situ Hybridization, and Reverse Transcription–Polymerase Chain Reaction for the Detection of Anaplastic Lymphoma Kinase Gene Rearrangements in Patients With Non–Small Cell Lung Cancer: Potential Advantages and Methodologic Pitfalls
- (2014) Irina Demidova et al. ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE
- Anaplastic lymphoma kinase gene rearrangements in cytological samples of non-small cell lung cancer: Comparison with histological assessment
- (2014) Agnese Proietti et al. CANCER CYTOPATHOLOGY
- Lung Cancers with ConcomitantEGFRMutations andALKRearrangements: Diverse Responses to EGFR-TKI and Crizotinib in Relation to Diverse Receptors Phosphorylation
- (2014) Jin-Ji Yang et al. CLINICAL CANCER RESEARCH
- A Comparison of Immunohistochemical Assays and FISH in Detecting the ALK Translocation in Diagnostic Histological and Cytological Lung Tumor Material
- (2014) John Le Quesne et al. Journal of Thoracic Oncology
- ALK/EML4 Fusion Gene May Be Found in Pure Squamous Carcinoma of the Lung
- (2014) Anna Caliò et al. Journal of Thoracic Oncology
- An International Interpretation Study Using the ALK IHC Antibody D5F3 and a Sensitive Detection Kit Demonstrates High Concordance between ALK IHC and ALK FISH and between Evaluators
- (2014) Murry W. Wynes et al. Journal of Thoracic Oncology
- Parallel FISH and Immunohistochemical Studies of ALK Status in 3244 Non–Small-Cell Lung Cancers Reveal Major Discordances
- (2014) Florian Cabillic et al. Journal of Thoracic Oncology
- Ceritinib in ALK-Rearranged Non–Small-Cell Lung Cancer
- (2014) Alice T. Shaw et al. NEW ENGLAND JOURNAL OF MEDICINE
- Accurate and Economical Detection of ALK Positive Lung Adenocarcinoma with Semiquantitative Immunohistochemical Screening
- (2014) Jianya Zhou et al. PLoS One
- The Molecular Detection and Clinical Significance of ALK Rearrangement in Selected Advanced Non-Small Cell Lung Cancer: ALK Expression Provides Insights into ALK Targeted Therapy
- (2014) Ning-Ning Zhang et al. PLoS One
- Diagnostic value of a novel fully automated immunochemistry assay for detection of ALK rearrangement in primary lung adenocarcinoma
- (2013) J. Ying et al. ANNALS OF ONCOLOGY
- Molecular Testing Guideline for Selection of Lung Cancer Patients for EGFR and ALK Tyrosine Kinase Inhibitors: Guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology
- (2013) Neal I. Lindeman et al. ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE
- Native and rearranged ALK copy number and rearranged cell count in non-small cell lung cancer
- (2013) D. Ross Camidge et al. CANCER
- ALK inhibitors in the treatment of advanced NSCLC
- (2013) Cesare Gridelli et al. CANCER TREATMENT REVIEWS
- ALK Rearrangements Are Mutually Exclusive with Mutations in EGFR or KRAS: An Analysis of 1,683 Patients with Non-Small Cell Lung Cancer
- (2013) J. F. Gainor et al. CLINICAL CANCER RESEARCH
- Recommendations for Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Update
- (2013) Antonio C. Wolff et al. JOURNAL OF CLINICAL ONCOLOGY
- Aberrant anaplastic lymphoma kinase expression in high-grade pulmonary neuroendocrine carcinoma
- (2013) Harumi Nakamura et al. JOURNAL OF CLINICAL PATHOLOGY
- Molecular genetic testing for lung adenocarcinomas: a practical approach to clinically relevant mutations and translocations
- (2013) Sanja Dacic JOURNAL OF CLINICAL PATHOLOGY
- ALK Status Testing in Non–Small Cell Lung Carcinoma
- (2013) Eugen C. Minca et al. JOURNAL OF MOLECULAR DIAGNOSTICS
- Interpretation of Anti-ALK Immunohistochemistry Results
- (2013) Kengo Takeuchi Journal of Thoracic Oncology
- Detection of ALK Rearrangement by Immunohistochemistry in Lung Adenocarcinoma and the Identification of a Novel EML4-ALK Variant
- (2013) Ka-Fai To et al. Journal of Thoracic Oncology
- Optimal Detection of ALK Rearranged Lung Adenocarcinomas
- (2013) Niki Karachaliou et al. Journal of Thoracic Oncology
- New Methods for ALK Status Diagnosis in Non–Small-Cell Lung Cancer: An Improved ALK Immunohistochemical Assay and a New, Brightfield, Dual ALK IHC–In Situ Hybridization Assay
- (2013) Hiroaki Nitta et al. Journal of Thoracic Oncology
- Detection of ALK-Positive Non–Small-Cell Lung Cancers on Cytological Specimens: High Accuracy of Immunocytochemistry with the 5A4 Clone
- (2013) Spasenija Savic et al. Journal of Thoracic Oncology
- Combined Use of ALK Immunohistochemistry and FISH for Optimal Detection of ALK-Rearranged Lung Adenocarcinomas
- (2013) Lynette M. Sholl et al. Journal of Thoracic Oncology
- Large-Scale Screening and Molecular Characterization of EML4-ALK Fusion Variants in Archival Non–Small-Cell Lung Cancer Tumor Specimens Using Quantitative Reverse Transcription Polymerase Chain Reaction Assays
- (2013) Tianhong Li et al. Journal of Thoracic Oncology
- Anaplastic lymphoma kinase (ALK) gene rearrangement in non-small cell lung cancer (NSCLC): Results of a multi-centre ALK-testing
- (2013) Maximilian v. Laffert et al. LUNG CANCER
- Testing for ALK rearrangement in lung adenocarcinoma: a multicenter comparison of immunohistochemistry and fluorescent in situ hybridization
- (2013) Christina I Selinger et al. MODERN PATHOLOGY
- Crizotinib versus Chemotherapy in Advanced ALK-Positive Lung Cancer
- (2013) Alice T. Shaw et al. NEW ENGLAND JOURNAL OF MEDICINE
- Fluorescence In Situ Hybridization and Immunohistochemistry as Diagnostic Methods for ALK Positive Non-Small Cell Lung Cancer Patients
- (2013) Pablo Martinez et al. PLoS One
- ALK-Rearranged Lung Cancer in Chinese: A Comprehensive Assessment of Clinicopathology, IHC, FISH and RT-PCR
- (2013) Yuan Li et al. PLoS One
- Comparison of IHC, FISH and RT-PCR Methods for Detection of ALK Rearrangements in 312 Non-Small Cell Lung Cancer Patients in Taiwan
- (2013) Yi-Cheng Wu et al. PLoS One
- A Rational Diagnostic Algorithm for the Identification of ALK Rearrangement in Lung Cancer: A Comprehensive Study of Surgically Treated Japanese Patients
- (2013) Kazuya Takamochi et al. PLoS One
- Immunohistochemistry reliably detects ALK rearrangements in patients with advanced non-small-cell lung cancer
- (2013) Xiao-Hong Han et al. VIRCHOWS ARCHIV
- Pemetrexed-based chemotherapy in patients with advanced, ALK-positive non-small cell lung cancer
- (2012) A. T. Shaw et al. ANNALS OF ONCOLOGY
- Comparison of Reverse Transcription-Polymerase Chain Reaction, Immunohistochemistry, and Fluorescence In Situ Hybridization Methodologies for Detection of Echinoderm Microtubule-Associated Proteinlike 4–Anaplastic Lymphoma Kinase Fusion–Positive Non–Small Cell Lung Carcinoma: Implications for Optimal Clinical Testing
- (2012) Michelle L. Wallander et al. ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE
- Discordance between anaplastic lymphoma kinase status in primary non-small-cell lung cancers and their corresponding metastases
- (2012) Hyojin Kim et al. HISTOPATHOLOGY
- TheALKtranslocation in advanced non-small-cell lung carcinomas: preapproval testing experience at a single cancer centre
- (2012) Esther Conde et al. HISTOPATHOLOGY
- A Dramatic Response to Crizotinib in a Non–Small-Cell Lung Cancer Patient with IHC-Positive and FISH-Negative ALK
- (2012) Jong-Mu Sun et al. Journal of Thoracic Oncology
- Immunohistochemistry is a Reliable Screening Tool for Identification of ALK Rearrangement in Non–Small-Cell Lung Carcinoma and is Antibody Dependent
- (2012) Chris M.J. Conklin et al. Journal of Thoracic Oncology
- Clinicoradiologic characteristics of patients with lung adenocarcinoma harboring EML4-ALK fusion oncogene
- (2012) Takayuki Fukui et al. LUNG CANCER
- Histologic and cytomorphologic features of ALK-rearranged lung adenocarcinomas
- (2012) Michiya Nishino et al. MODERN PATHOLOGY
- EML4-ALK testing in non-small cell carcinomas of the lung: a review with recommendations
- (2012) Erik Thunnissen et al. VIRCHOWS ARCHIV
- A Screening Method for the ALK Fusion Gene in NSCLC
- (2012) Yoshiko Murakami et al. Frontiers in Oncology
- Comprehensive Histologic Analysis of ALK-Rearranged Lung Carcinomas
- (2011) Akihiko Yoshida et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- Screening of Anaplastic Lymphoma Kinase Rearrangement by Immunohistochemistry in Non-small Cell Lung Cancer: Correlation with Fluorescence In Situ Hybridization
- (2011) Jin Ho Paik et al. Journal of Thoracic Oncology
- International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society International Multidisciplinary Classification of Lung Adenocarcinoma
- (2011) William D. Travis et al. Journal of Thoracic Oncology
- Dual IHC and FISH Testing for ALK Gene Rearrangement in Lung Adenocarcinomas in a Routine Practice: A French Study
- (2011) Anne McLeer-Florin et al. Journal of Thoracic Oncology
- Clinicopathologic implication of ALK rearrangement in surgically resected lung cancer
- (2011) Jin Ho Paik et al. LUNG CANCER
- Achieving 95% Cross-Methodological Concordance in HER2 Testing
- (2010) Erin E. Grimm et al. AMERICAN JOURNAL OF CLINICAL PATHOLOGY
- Human Epidermal Growth Factor Receptor 2 Testing: Where Are We?
- (2010) Pradip De et al. JOURNAL OF CLINICAL ONCOLOGY
- Assessment of EGFR Mutation Status in Lung Adenocarcinoma by Immunohistochemistry Using Antibodies Specific to the Two Major Forms of Mutant EGFR
- (2010) Marie Brevet et al. JOURNAL OF MOLECULAR DIAGNOSTICS
- Increased ALK Gene Copy Number and Amplification are Frequent in Non-small Cell Lung Cancer
- (2010) Marta Salido et al. Journal of Thoracic Oncology
- TheEML4-ALKfusion gene is involved in various histologic types of lung cancers from nonsmokers with wild-typeEGFRandKRAS
- (2009) Daisy Wing-Sze Wong et al. CANCER
- Unique Clinicopathologic Features Characterize ALK-Rearranged Lung Adenocarcinoma in the Western Population
- (2009) S. J. Rodig et al. CLINICAL CANCER RESEARCH
- Guidelines for Human Epidermal Growth Factor Receptor 2 Testing: Biologic and Methodologic Considerations
- (2009) Guido Sauter et al. JOURNAL OF CLINICAL ONCOLOGY
- EML4-ALK lung cancers are characterized by rare other mutations, a TTF-1 cell lineage, an acinar histology and young onset
- (2009) Kentaro Inamura et al. MODERN PATHOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now