Article
Veterinary Sciences
Takeshi Tsuka, Hiroichi Ozaki, Daisuke Saito, Toshiyuki Murase, Yoshiharu Okamoto, Kazuo Azuma, Tomohiro Osaki, Norihiko Ito, Yusuke Murahata, Tomohiro Imagawa
Summary: CTX-M-2-producing Klebsiella oxytoca strains with high ESBL production rates may spread clonally within a farm, while the bla(CTX-M-2) gene in Klebsiella pneumoniae may disseminate among farms through different plasmids. Monitoring ESBL genes, including bla(CTX-M-2), among causative agents of bacterial mastitis in cows can help develop relevant treatments and control practices.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Review
Veterinary Sciences
Kai Liu, Limei Zhang, Xiaolong Gu, Weijie Qu
Summary: Understanding the distribution and antimicrobial resistance rates of Klebsiella spp. associated with bovine mastitis in China is crucial for treatment decision-making and control programs. This meta-analysis revealed a high prevalence of Klebsiella spp. in China, particularly in South China and clinical cases. The study also found high levels of antimicrobial resistance in Klebsiella spp. towards various antibiotics. These findings have important implications for the development and implementation of strategies to control bovine mastitis caused by Klebsiella spp. in China.
FRONTIERS IN VETERINARY SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Efstathia Tsakali, Andreas G. Tsantes, Dimitra Houhoula, George P. Laliotis, Anthimia Batrinou, Panagiotis Halvatsiotis, Argyrios E. Tsantes
Summary: Milk is a suitable medium for bacterial growth, and mastitis is a significant issue in the dairy industry. By analyzing milk samples from different lactating animals, it was found that environmental hygiene plays a vital role, as certain pathogens related to poor hygiene were detected. The presence of these pathogens highlights the importance of safety testing and monitoring processes.
APPLIED SCIENCES-BASEL
(2023)
Article
Veterinary Sciences
Gulten Okmen, Daniela Giannetto, Francesco Fazio, Kutbettin Arslan
Summary: Mastitis is a costly and significant disease for dairy herds, primarily caused by bacteria, and commonly treated with antibiotics. To avoid antibiotic resistance and residues, natural plant extracts are being explored as alternative treatments. This study investigates the antioxidant and antibacterial properties of pomegranate flower extracts against mastitis pathogens.
VETERINARY SCIENCES
(2023)
Article
Engineering, Multidisciplinary
Shikai Song, Wenjuan He, Dawei Yang, Manar Benmouffok, Yao Wang, Jiyun Li, Chengtao Sun, Xiangbin Song, Shizhen Ma, Chang Cai, Shuangyang Ding, Congming Wu, Zhangqi Shen, Yang Wang
Summary: This study investigated the prevalence and molecular characteristics of Klebsiella pneumoniae in clinical mastitis milk samples from dairy cattle in northern China. The majority of K. pneumoniae isolates in clinical mastitis belonged to the KpI phylogroup, with few isolates posing a threat to human health. Bovine KpII-B isolates shared a high level of nucleotide sequence identity with isolates from human infections and frequently carried the nitrogen-fixation gene.
Article
Agriculture, Dairy & Animal Science
S. Nakada, Y. Fujimoto, J. Kohara, K. Makita
Summary: Bovine leukemia virus (BLV) is prevalent on Japanese dairy farms and causes bovine leukosis and immunosuppression. This study found that cows with high proviral load of BLV were more susceptible to subclinical mastitis than non-infected and low-proviral-load cows, leading to significant economic losses.
JOURNAL OF DAIRY SCIENCE
(2023)
Article
Microbiology
Zhiyi Zheng, Patrick J. Gorden, Xiaoqin Xia, Ying Zheng, Ganwu Li
Summary: This study sequenced 180 Klebsiella pneumoniae strains isolated from dairy cattle mastitis milk in 11 U.S. states, revealing the genomic features and diversity of this population. The analysis showed a higher genomic diversity in bovine mastitis strains, with gene units associated with ferric citrate uptake, lactose fermentation, and heavy metal resistance. The findings highlight the potential for developing novel diagnostic tools and preventive strategies for mastitis-causing K. pneumoniae strains.
ENVIRONMENTAL MICROBIOLOGY
(2022)
Article
Veterinary Sciences
Yuxiang Shi, Wenpeng Zhao, Gang Liu, Tariq Ali, Peng Chen, Yongxia Liu, John P. Kastelic, Bo Han, Jian Gao
Summary: The bacteriophages CM8-1 and SJT-2 were found to mitigate K. pneumoniae-induced inflammation in bMECs, reducing bacterial adhesion and invasion, cytotoxicity, and inflammatory responses. The study suggests the potential of these bacteriophages for treating mastitis in cows should be evaluated in clinical trials.
BMC VETERINARY RESEARCH
(2021)
Article
Veterinary Sciences
Tingrui Zhang, Guoyi Niu, Sukolrat Boonyayatra, Duangporn Pichpol
Summary: The study found that S. uberis showed resistance to tetracycline and ceftiofur, with resistance levels increasing from 2010 to 2017. The most common antimicrobial resistance gene in S. uberis was tetM, with a significant increase in detection rates during the study period.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Multidisciplinary Sciences
Saddam Saddam, Muddasir Khan, Muhsin Jamal, Sadeeq Ur Rehman, Petr Slama, Pavel Horky
Summary: The present study investigated the occurrence of Multidrug-resistant (MDR) Klebsiella pneumoniae and its capsular resistance genes in cow farms in district Peshawar, Pakistan. Out of 700 milk samples from symptomatic mastitic cows, 180 (25.7%) were found to be infected with K. pneumoniae, with 80 (44.4%) of them being MDR strains. The analysis also revealed high resistance to Vancomycin (95%) and high sensitivity to Ceftazidime (80%). The presence of MDR K. pneumoniae combined with capsular genes may pose a potential threat to dairy farm animals and humans, emphasizing the importance of hygienic practices in livestock management.
Review
Immunology
Muhammad Zahoor Khan, Jingjun Wang, Yulin Ma, Tianyu Chen, Mei Ma, Qudrat Ullah, Ibrar Muhammad Khan, Adnan Khan, Zhijun Cao, Shuai Liu
Summary: Bovine mastitis is a contagious disease that causes inflammation of the mammary gland in dairy cattle, leading to changes in milk composition and udder tissues. Mastitis is associated with depressed immunity, elevated levels of inflammatory cytokines, and increased somatic cell count in milk. Traditional breeding for mastitis resistance is challenging due to low heritability, but genetic-marker-selective breeding and genomic selection have shown promise in improving host genetics and identifying genetically resistant animals. This review discusses candidate genes and signaling pathways related to mastitis resistance and susceptibility in dairy cattle.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Microbiology
Anneke Luecken, Nicole Wente, Yanchao Zhang, Svenja Woudstra, Volker Kroemker
Summary: Through a study on species differentiation within Corynebacterium spp., it was found that C. bovis and C. amycolatum are the main species, showing significant differences in udder health groups. Considering somatic cell count, it was observed that C. bovis and C. amycolatum have different patterns of infection in clinical mastitis.
Article
Agriculture, Dairy & Animal Science
Wenpeng Zhao, Yuxiang Shi, Gang Liu, Jingyue Yang, Bing Yi, Yongxia Liu, John P. Kastelic, Bo Han, Jian Gao
Summary: The bacteriophage CM8-1 isolated from dairy farm wastewater showed promising results in treating murine K. pneumoniae mastitis by reducing bacterial counts, improving mammary gland tissue morphology, and decreasing expression of pro-inflammatory factors. The phage had stable biological characteristics and effectively suppressed K. pneumoniae mastitis when administered into the mammary gland in mice 2 hours after bacterial inoculation.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Agriculture, Dairy & Animal Science
Rodrigo M. Souza, Fernando N. Souza, Camila F. Batista, Sofie Piepers, Anneleen De Visscher, Kamila R. Santos, Paula C. Molinari, Jose A. Ferronatto, Adriano Franca da Cunha, Maiara G. Blagitz, Guilherme G. da Silva, Francisco P. Renno, Monica M. O. P. Cerqueira, Marcos B. Heinemann, Sarne De Vliegher, Alice M. M. P. Della Libera
Summary: This study investigated the ability of different staphylococcal species to evade host defense mechanisms in dairy cows, specifically focusing on phagocytosis resistance and triggering of reactive oxygen species (ROS) production. The findings suggest that different staphylococcal species have varying abilities to resist phagocytosis and induce ROS production, which may contribute to their persistence and inflammation in causing mastitis.
JOURNAL OF DAIRY SCIENCE
(2022)
Article
Biochemistry & Molecular Biology
Yasmin Neves Vieira Sabino, Katialaine Correa de Araujo Domingues, Harsh Mathur, Laura G. Gomez-Mascaraque, Gaetan Drouin, Antonio Martinez-Abad, Marcos Rogerio Totola, Lucas Magalhaes Abreu, Paul D. Cotter, Hilario Cuquetto Mantovani
Summary: This study demonstrates the potential of exopolysaccharides (EPS) produced by Bacillus spp. as anti-biofilm compounds against Staphylococcus aureus associated with bovine mastitis, offering potential applications in the treatment of this costly disease.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Infectious Diseases
Peter Daley, Carla Penney, Susan Wakeham, Glenda Compton, Aaron McKim, Judy O'Keefe, Brendan Barrett, Lindsay Nicolle
CANADIAN JOURNAL OF INFECTIOUS DISEASES & MEDICAL MICROBIOLOGY
(2015)
Article
Infectious Diseases
Peter Daley, Vijayakumar Jagannathan, K. R. John, Joy Sarojini, Asha Latha, Reinhold Vieth, Shirly Suzana, Lakshmanan Jeyaseelan, Devasahayam J. Christopher, Marek Smieja, Dilip Mathai
LANCET INFECTIOUS DISEASES
(2015)
Article
Public, Environmental & Occupational Health
Peter Daley, Janak Bajgai, Carla Penney, Karen Williams, Hugh Whitney, George R. Golding, Scott Weese
Article
Infectious Diseases
Ripa Akter, Paul Boland, Peter Daley, Proton Rahman, Nayef Al Ghanim
CANADIAN JOURNAL OF INFECTIOUS DISEASES & MEDICAL MICROBIOLOGY
(2016)
Article
Infectious Diseases
Carla Penney, Robert Porter, Mary O'Brien, Peter Daley
CANADIAN JOURNAL OF INFECTIOUS DISEASES & MEDICAL MICROBIOLOGY
(2016)
Article
Infectious Diseases
Peter Daley, Adam Comerford, Jurgienne Umali, Carla Penney
CANADIAN JOURNAL OF INFECTIOUS DISEASES & MEDICAL MICROBIOLOGY
(2016)
Article
Public, Environmental & Occupational Health
J. M. Hughes, C. Penney, S. Boyd, P. Daley
EPIDEMIOLOGY AND INFECTION
(2018)
Article
Infectious Diseases
Stephen Duffett, Bayan Missaghi, Peter Daley
CANADIAN JOURNAL OF INFECTIOUS DISEASES & MEDICAL MICROBIOLOGY
(2012)
Article
Infectious Diseases
N. Stall, T. Rubin, J. S. Michael, D. Mathai, O. C. Abraham, P. Mathews, K. Thomas, M. John, P. Daley
INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE
(2011)
Article
Respiratory System
David A. Jolliffe, Davaasambuu Ganmaa, Christian Wejse, Rubhana Raqib, M. Ahsanul Haq, Nawal Salahuddin, Peter K. Daley, Anna P. Ralph, Thomas R. Ziegler, Adrian R. Martineau
EUROPEAN RESPIRATORY JOURNAL
(2019)
Article
Public, Environmental & Occupational Health
Claire L. Pratt, Zahra Rehan, Lydia Xing, Laura Gilbert, Brenda Fillier, Brendan Barrett, Peter Daley
Summary: Modified reporting of positive urine cultures collected from indwelling catheters improved the appropriateness of treatment decisions and may be safe.
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY
(2021)
Article
Respiratory System
Jonathon R. Campbell, Christopher Pease, Peter Daley, Madhukar Pai, Dick Menzies
CANADIAN JOURNAL OF RESPIRATORY CRITICAL CARE AND SLEEP MEDICINE
(2022)
Article
Infectious Diseases
Zahra Rehan, Claire Pratt, Kim Babb, Brenda Filier, Laura Gilbert, Robert Wilson, Peter Daley
Summary: This study aimed to evaluate the impact of modified urine culture reporting on the appropriateness of treatment for asymptomatic bacteriuria (ASB) and urinary tract infection (UTI) in long-term care facilities. The results showed that modified reporting improved the appropriateness of treatment by reducing treatment of ASB, but the difference was not significant. Many LTCF prescribers still preferred standard reporting.
JAC-ANTIMICROBIAL RESISTANCE
(2022)
Meeting Abstract
Rheumatology
Ripa Akter, Paul Boland, Peter Daley, Proton Rahman, Nayef Al Ghanim
JOURNAL OF RHEUMATOLOGY
(2016)