Cooperation of Tyrosine Kinase Receptor TrkB and Epidermal Growth Factor Receptor Signaling Enhances Migration and Dispersal of Lung Tumor Cells

The Dormancy Dilemma: Quiescence versus Balanced Proliferation

(2013) Alan Wells et al.   CANCER RESEARCH

New Pathologic Classification of Lung Cancer: Relevance for Clinical Practice and Clinical Trials

(2013) William D. Travis et al.   JOURNAL OF CLINICAL ONCOLOGY

EGF transactivation of Trk receptors regulates the migration of newborn cortical neurons

(2013) Dirk Puehringer et al.   NATURE NEUROSCIENCE

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Tumor Microenvironment Complexity: Emerging Roles in Cancer Therapy

(2012) M. A. Swartz et al.   CANCER RESEARCH

Expression of TrkB and BDNF is associated with poor prognosis in non-small cell lung cancer

(2012) Kyoko Okamura et al.   LUNG CANCER

Tumor Metastasis: Molecular Insights and Evolving Paradigms

(2011) Scott Valastyan et al.   CELL

Role and Relevance of TrkB Mutations and Expression in Non-Small Cell Lung Cancer

(2011) T. Harada et al.   CLINICAL CANCER RESEARCH

Molecular Biology of Lung Cancer: Clinical Implications

(2011) Jill E. Larsen et al.   CLINICS IN CHEST MEDICINE

Zeb1 is required for TrkB-induced epithelial-mesenchymal transition, anoikis resistance and metastasis

(2011) M A Smit et al.   ONCOGENE

Functional Characterization of Human Cancer-Derived TRKB Mutations

(2011) Thomas R. Geiger et al.   PLoS One

FGF-1 reverts epithelial-mesenchymal transition induced by TGF-β1 through MAPK/ERK kinase pathway

(2010) Carlos Ramos et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Overexpression of TrkB promotes the progression of colon cancer

(2010) YINGJIAO YU et al.   APMIS

TrkB is highly expressed in NSCLC and mediates BDNF-induced the activation of Pyk2 signaling and the invasion of A549 cells

(2010) Siyang Zhang et al.   BMC CANCER

Differential susceptibility to epithelial-mesenchymal transition (EMT) of alveolar, bronchial and intestinal epithelial cells in vitro and the effect of angiotensin II receptor inhibition

(2010) Stephen T. Buckley et al.   CELL AND TISSUE RESEARCH

EGF receptor activation by GPCRs: An universal pathway reveals different versions

(2010) Claus Liebmann   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Neurotrophin receptors TrkA and TrkC cause neuronal death whereas TrkB does not

(2010) Vassiliki Nikoletopoulou et al.   NATURE

On Trk--The TrkB Signal Transduction Pathway Is an Increasingly Important Target in Cancer Biology

(2009) C. J. Thiele et al.   CLINICAL CANCER RESEARCH

Trk Receptor Expression and Inhibition in Neuroblastomas

(2009) G. M. Brodeur et al.   CLINICAL CANCER RESEARCH

Integrin α3β1–dependent β-catenin phosphorylation links epithelial Smad signaling to cell contacts

(2009) Young Kim et al.   JOURNAL OF CELL BIOLOGY

A Twist-Snail Axis Critical for TrkB-Induced Epithelial-Mesenchymal Transition-Like Transformation, Anoikis Resistance, and Metastasis

(2009) M. A. Smit et al.   MOLECULAR AND CELLULAR BIOLOGY

CCM2 Mediates Death Signaling by the TrkA Receptor Tyrosine Kinase

(2009) Liraz Harel et al.   NEURON

Frequent mutations in the neurotrophic tyrosine receptor kinase gene family in large cell neuroendocrine carcinoma of the lung

(2008) Antonio Marchetti et al.   HUMAN MUTATION

Somatic mutations affect key pathways in lung adenocarcinoma

(2008) Li Ding et al.   NATURE

Lung Cancer

(2008) Roy S. Herbst et al.   NEW ENGLAND JOURNAL OF MEDICINE

Overexpression of Tyrosine Kinase B Protein as a Predictor for Distant Metastases and Prognosis in Gastric Carcinoma

(2008) Yong Zhang et al.   ONCOLOGY

Collagen I Promotes Epithelial-to-Mesenchymal Transition in Lung Cancer Cells via Transforming Growth Factor–β Signaling

(2007) Yasushi Shintani et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY