Genetic Deletion of Transglutaminase 2 Does Not Rescue the Phenotypic Deficits Observed in R6/2 and zQ175 Mouse Models of Huntington's Disease

Neuronal aggregates are associated with phenotypic onset in the R6/2 Huntington's disease transgenic mouse

(2012) Randi-Michelle Cowin et al.   BEHAVIOURAL BRAIN RESEARCH

Type 2 transglutaminase is involved in the autophagy-dependent clearance of ubiquitinated proteins

(2012) M D'Eletto et al.   CELL DEATH AND DIFFERENTIATION

Tissue transglutaminase overexpression does not modify the disease phenotype of the R6/2 mouse model of Huntington's disease

(2012) Ashish Kumar et al.   EXPERIMENTAL NEUROLOGY

Discovery and Structure–Activity Relationship of Potent and Selective Covalent Inhibitors of Transglutaminase 2 for Huntington’s Disease

(2012) Michael E. Prime et al.   JOURNAL OF MEDICINAL CHEMISTRY

Comprehensive Behavioral and Molecular Characterization of a New Knock-In Mouse Model of Huntington’s Disease: zQ175

(2012) Liliana B. Menalled et al.   PLoS One

Characterization of Neurophysiological and Behavioral Changes, MRI Brain Volumetry and 1H MRS in zQ175 Knock-In Mouse Model of Huntington's Disease

(2012) Taneli Heikkinen et al.   PLoS One

Mutant huntingtin causes defective actin remodeling during stress: defining a new role for transglutaminase 2 in neurodegenerative disease

(2011) Lise Munsie et al.   HUMAN MOLECULAR GENETICS

Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease

(2010) Stephen J. McConoughey et al.   EMBO Molecular Medicine

Responses to Environmental Enrichment Differ with Sex and Genotype in a Transgenic Mouse Model of Huntington's Disease

(2010) Nigel I. Wood et al.   PLoS One

Identical oligomeric and fibrillar structures captured from the brains of R6/2 and knock-in mouse models of Huntington's disease

(2009) Kirupa Sathasivam et al.   HUMAN MOLECULAR GENETICS

Brain-derived neurotrophic factor in neurodegenerative diseases

(2009) Chiara Zuccato et al.   Nature Reviews Neurology

Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models

(2009) Liliana Menalled et al.   NEUROBIOLOGY OF DISEASE

Increased levels of γ-glutamylamines in Huntington disease CSF

(2008) Thomas M. Jeitner et al.   JOURNAL OF NEUROCHEMISTRY

Paradoxical delay in the onset of disease caused by super-long CAG repeat expansions in R6/2 mice

(2008) A Jennifer Morton et al.   NEUROBIOLOGY OF DISEASE

CAG repeat lengths ≥335 attenuate the phenotype in the R6/2 Huntington's disease transgenic mouse

(2008) I. Dragatsis et al.   NEUROBIOLOGY OF DISEASE