Adenovirus-Mediated Efficient Gene Transfer into Cultured Three-Dimensional Organoids

Modulation of β-Catenin Signaling by the Inhibitors of MAP Kinase, Tyrosine Kinase, and PI3-Kinase Pathways

(2014) Wenwen Zhang et al.   International Journal of Medical Sciences

The Intestinal Crypt, A Prototype Stem Cell Compartment

(2013) Hans Clevers   CELL

Reprogramming Fibroblasts into Bipotential Hepatic Stem Cells by Defined Factors

(2013) Bing Yu et al.   Cell Stem Cell

Destabilization of Heterologous Proteins Mediated by the GSK3� Phosphorylation Domain of the �-Catenin Protein

(2013) Yuhan Kong et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The E-F Hand Calcium-Binding Protein S100A4 Regulates the Proliferation, Survival and Differentiation Potential of Human Osteosarcoma Cells

(2013) Xian Chen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Repurposing CRISPR/Cas9 for in situ functional assays

(2013) A. Malina et al.   GENES & DEVELOPMENT

Vascularized and functional human liver from an iPSC-derived organ bud transplant

(2013) Takanori Takebe et al.   NATURE

Cerebral organoids model human brain development and microcephaly

(2013) Madeline A. Lancaster et al.   NATURE

Cas9 as a versatile tool for engineering biology

(2013) Prashant Mali et al.   NATURE METHODS

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Crosstalk between Wnt/β-Catenin and Estrogen Receptor Signaling Synergistically Promotes Osteogenic Differentiation of Mesenchymal Progenitor Cells

(2013) Yanhong Gao et al.   PLoS One

Growing Self-Organizing Mini-Guts from a Single Intestinal Stem Cell: Mechanism and Applications

(2013) T. Sato et al.   SCIENCE

ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering

(2013) Thomas Gaj et al.   TRENDS IN BIOTECHNOLOGY

RNA-dependent DNA endonuclease Cas9 of the CRISPR system: Holy Grail of genome editing?

(2013) Giedrius Gasiunas et al.   TRENDS IN MICROBIOLOGY

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

(2011) Toshiro Sato et al.   GASTROENTEROLOGY

Controlled gene expression in primary Lgr5 organoid cultures

(2011) Bon-Kyoung Koo et al.   NATURE METHODS

State-of-the-art gene-based therapies: the road ahead

(2011) Mark A. Kay   NATURE REVIEWS GENETICS

Lgr5+ve Stem Cells Drive Self-Renewal in the Stomach and Build Long-Lived Gastric Units In Vitro

(2010) Nick Barker et al.   Cell Stem Cell

Intestinal lineage commitment of embryonic stem cells

(2010) Li Cao et al.   DIFFERENTIATION

Tetrandrine Inhibits Wnt/ -Catenin Signaling and Suppresses Tumor Growth of Human Colorectal Cancer

(2010) B.-C. He et al.   MOLECULAR PHARMACOLOGY

Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts

(2010) Toshiro Sato et al.   NATURE

Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro

(2010) Jason R. Spence et al.   NATURE

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

(2009) Toshiro Sato et al.   NATURE

BMP-9-induced osteogenic differentiation of mesenchymal progenitors requires functional canonical Wnt/β-catenin signalling

(2008) Ni Tang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

A Comprehensive Analysis of the Dual Roles of BMPs in Regulating Adipogenic and Osteogenic Differentiation of Mesenchymal Progenitor Cells

(2008) Quan Kang et al.   STEM CELLS AND DEVELOPMENT