Quantification of Dynamic Morphological Drug Responses in 3D Organotypic Cell Cultures by Automated Image Analysis

An Analytical Approach Differentiates Between Individual and Collective Cancer Invasion

(2015) Elad Katz et al.   Analytical Cellular Pathology

Targeting of Rac GTPases blocks the spread of intact human breast cancer

(2015) Elad Katz et al.   Oncotarget

Deconstructing Dimensionality

(2013) M. A. Schwartz et al.   SCIENCE

Inhibition of PI3K/mTOR Leads to Adaptive Resistance in Matrix-Attached Cancer Cells

(2012) Taru Muranen et al.   CANCER CELL

Vav3-Rac1 Signaling Regulates Prostate Cancer Metastasis with Elevated Vav3 Expression Correlating with Prostate Cancer Progression and Posttreatment Recurrence

(2012) K.-T. Lin et al.   CANCER RESEARCH

OrganDots – an organotypic 3D tissue culture platform for drug development

(2012) Lars Sundstrom et al.   Expert Opinion on Drug Discovery

Deconstructing the third dimension – how 3D culture microenvironments alter cellular cues

(2012) Brendon M. Baker et al.   JOURNAL OF CELL SCIENCE

Into the deep: Refocusing on 3D

(2012) Joan S. Brugge   NATURE CELL BIOLOGY

Epcam, CD44, and CD49f Distinguish Sphere-Forming Human Prostate Basal Cells from a Subpopulation with Predominant Tubule Initiation Capability

(2012) Changyong Guo et al.   PLoS One

Using Magnetic Levitation for Three Dimensional Self-Assembly

(2011) Katherine A. Mirica et al.   ADVANCED MATERIALS

ROCK Inhibitor and Feeder Cells Induce the Conditional Reprogramming of Epithelial Cells

(2011) Xuefeng Liu et al.   AMERICAN JOURNAL OF PATHOLOGY

Improved structure, function and compatibility for CellProfiler: modular high-throughput image analysis software

(2011) Lee Kamentsky et al.   BIOINFORMATICS

Determining tamoxifen sensitivity using primary breast cancer tissue in collagen-based three-dimensional culture

(2011) Alexander D. Leeper et al.   BIOMATERIALS

Towards automated production and drug sensitivity testing using scaffold-free spherical tumor microtissues

(2011) Maren Drewitz et al.   Biotechnology Journal

Cancer Invasion and the Microenvironment: Plasticity and Reciprocity

(2011) Peter Friedl et al.   CELL

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

(2011) Toshiro Sato et al.   GASTROENTEROLOGY

In vitro three-dimensional (3D) models in cancer research: An update

(2011) Lauren C. Kimlin et al.   MOLECULAR CARCINOGENESIS

Balancing forces: architectural control of mechanotransduction

(2011) Christopher C. DuFort et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lysophosphatidic acid and sphingosine-1-phosphate promote morphogenesis and block invasion of prostate cancer cells in three-dimensional organotypic models

(2011) V Härmä et al.   ONCOGENE

Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion

(2011) M Björkman et al.   ONCOGENE

An In Vitro Model That Recapitulates the Epithelial to Mesenchymal Transition (EMT) in Human Breast Cancer

(2011) Elad Katz et al.   PLoS One

Cancer invasion and resistance: interconnected processes of disease progression and therapy failure

(2011) Stephanie Alexander et al.   TRENDS IN MOLECULAR MEDICINE

Changes in cortical cytoskeletal and extracellular matrix gene expression in prostate cancer are related to oncogenic ERG deregulation

(2010) Wolfgang A Schulz et al.   BMC CANCER

Mammosphere-forming cells from breast cancer cell lines as a tool for the identification of CSC-like- and early progenitor-targeting drugs

(2010) Mario Cioce et al.   CELL CYCLE

Cellular mechanisms regulating epithelial morphogenesis and cancer invasion

(2010) Ryan S Gray et al.   CURRENT OPINION IN CELL BIOLOGY

Dynamic interplay between the collagen scaffold and tumor evolution

(2010) Mikala Egeblad et al.   CURRENT OPINION IN CELL BIOLOGY

Current trends in mathematical modeling of tumor–microenvironment interactions: a survey of tools and applications

(2010) Katarzyna A Rejniak et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

A Review of Three-Dimensional In Vitro Tissue Models for Drug Discovery and Transport Studies

(2010) Nelita T. Elliott et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

A Novel Role for Wnt/Ca2+ Signaling in Actin Cytoskeleton Remodeling and Cell Motility in Prostate Cancer

(2010) Qin Wang et al.   PLoS One

A Comprehensive Panel of Three-Dimensional Models for Studies of Prostate Cancer Growth, Invasion and Drug Responses

(2010) Ville Härmä et al.   PLoS One

Matrigel: A complex protein mixture required for optimal growth of cell culture

(2010) Chris S. Hughes et al.   PROTEOMICS

Enrichment for Breast Cancer Cells with Stem/Progenitor Properties by Differential Adhesion

(2010) Vijay Walia et al.   STEM CELLS AND DEVELOPMENT

Linking Changes in Epithelial Morphogenesis to Cancer Mutations Using Computational Modeling

(2010) Katarzyna A. Rejniak et al.   PLoS Computational Biology

Molecular Predictors of 3D Morphogenesis by Breast Cancer Cell Lines in 3D Culture

(2010) Ju Han et al.   PLoS Computational Biology

WNT signaling regulates self-renewal and differentiation of prostate cancer cells with stem cell characteristics

(2009) Isabelle Bisson et al.   CELL RESEARCH

PAK1 and PAK2 have different roles in HGF-induced morphological responses

(2009) Michael D. Bright et al.   CELLULAR SIGNALLING

Quantification and its Applications in Fluorescent Microscopy Imaging

(2009) Nicholas Hamilton   TRAFFIC

Extracellular matrix control of mammary gland morphogenesis and tumorigenesis: insights from imaging

(2008) Cyrus M. Ghajar et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Radial symmetries based decomposition of cell clusters in binary and gray level images

(2007) Oliver Schmitt et al.   PATTERN RECOGNITION