Mechanisms of U87 Astrocytoma Cell Uptake and Trafficking of Monomeric versus Protofibril Alzheimer’s Disease Amyloid-β Proteins

AP-2β regulates amyloid beta-protein stimulation of apolipoprotein E transcription in astrocytes

(2012) Ximena S. Rossello et al.   BRAIN RESEARCH

Low-density Lipoprotein Receptor Represents an Apolipoprotein E-independent Pathway of Aβ Uptake and Degradation by Astrocytes

(2012) Jacob M. Basak et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

LRP1 in Brain Vascular Smooth Muscle Cells Mediates Local Clearance of Alzheimer's Amyloid- 

(2012) T. Kanekiyo et al.   JOURNAL OF NEUROSCIENCE

Differences in the Cellular Uptake and Intracellular Itineraries of Amyloid Beta Proteins 40 and 42: Ramifications for the Alzheimer’s Drug Discovery

(2012) Rajesh S. Omtri et al.   MOLECULAR PHARMACEUTICS

Natural Amyloid-Beta Oligomers Acutely Impair the Formation of a Contextual Fear Memory in Mice

(2012) Kara A. Kittelberger et al.   PLoS One

Mitochondria-Specific Accumulation of Amyloid β Induces Mitochondrial Dysfunction Leading to Apoptotic Cell Death

(2012) Moon-Yong Cha et al.   PLoS One

The effect of amyloid associated proteins on the expression of genes involved in amyloid-β clearance by adult human astrocytes

(2011) Sandra D. Mulder et al.   EXPERIMENTAL NEUROLOGY

Apolipoprotein E Promotes β-Amyloid Trafficking and Degradation by Modulating Microglial Cholesterol Levels

(2011) C. Y. Daniel Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Soluble Aβ oligomer production and toxicity

(2011) Megan E. Larson et al.   JOURNAL OF NEUROCHEMISTRY

Inhibition of β-amyloid1-42 internalization attenuates neuronal death by stabilizing the endosomal-lysosomal system in rat cortical cultured neurons

(2011) M.S. Song et al.   NEUROSCIENCE

The p75NTR extracellular domain

(2011) Xin-Fu Zhou et al.   Prion

The role of microglia in amyloid clearance from the AD brain

(2010) C. Y. Daniel Lee et al.   JOURNAL OF NEURAL TRANSMISSION

Norepinephrine Promotes Microglia to Uptake and Degrade Amyloid   Peptide through Upregulation of Mouse Formyl Peptide Receptor 2 and Induction of Insulin-Degrading Enzyme

(2010) Y. Kong et al.   JOURNAL OF NEUROSCIENCE

Endocytic pathways mediating oligomeric Abeta42 neurotoxicity

(2010) Chunjiang Yu et al.   Molecular Neurodegeneration

Amyloid β-peptide levels in laser capture microdissected cornu ammonis 1 pyramidal neurons of Alzheimerʼs brain

(2010) Mikio Aoki et al.   NEUROREPORT

Roles of AP-2 in Clathrin-Mediated Endocytosis

(2010) Emmanuel Boucrot et al.   PLoS One

Limitations of MTT and MTS-Based Assays for Measurement of Antiproliferative Activity of Green Tea Polyphenols

(2010) Piwen Wang et al.   PLoS One

Low-Density Lipoprotein Receptor-Related Protein 1 (LRP1) Mediates Neuronal Aβ42 Uptake and Lysosomal Trafficking

(2010) Rodrigo A. Fuentealba et al.   PLoS One

Receptor-associated Protein Interacts with Amyloid-β Peptide and Promotes Its Cellular Uptake

(2009) Takahisa Kanekiyo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ca2+ Regulation of Dynamin-Independent Endocytosis in Cortical Astrocytes

(2009) M. Jiang et al.   JOURNAL OF NEUROSCIENCE

Microglia Mediate the Clearance of Soluble A  through Fluid Phase Macropinocytosis

(2009) S. Mandrekar et al.   JOURNAL OF NEUROSCIENCE

Disruption of fast axonal transport is a pathogenic mechanism for intraneuronal amyloid beta

(2009) G. Pigino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Binding and uptake of Aβ1-42 by primary human astrocytesin vitro

(2008) Henrietta M. Nielsen et al.   GLIA

Aβ1–42 reduces synapse number and inhibits neurite outgrowth in primary cortical and hippocampal neurons: A quantitative analysis

(2008) Nicholas A. Evans et al.   JOURNAL OF NEUROSCIENCE METHODS

Isoform and Splice-Variant Specific Functions of Dynamin-2 Revealed by Analysis of Conditional Knock-Out Cells

(2008) Ya-Wen Liu et al.   MOLECULAR BIOLOGY OF THE CELL

Immunization in Alzheimer's disease: naïve hope or realistic clinical potential?

(2008) J K Foster et al.   MOLECULAR PSYCHIATRY

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE