TERT Promoter Mutations Lead to High Transcriptional Activity under Hypoxia and Temozolomide Treatment and Predict Poor Prognosis in Gliomas

TERT Promoter Mutations Occur Early in Urothelial Neoplasia and Are Biomarkers of Early Disease and Disease Recurrence in Urine

(2013) I. Kinde et al.   CANCER RESEARCH

Correlation between chemosensitivity to anticancer drugs and telomerase reverse transcriptase mRNA expression in gastric cancer

(2013) Lin Wang et al.   Diagnostic Pathology

PMA and Ionomycin Induce Glioblastoma Cell Death: Activation-Induced Cell-Death-Like Phenomena Occur in Glioma Cells

(2013) Sheng Han et al.   PLoS One

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

(2013) P. J. Killela et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TERT Promoter Mutations in Familial and Sporadic Melanoma

(2013) S. Horn et al.   SCIENCE

Highly Recurrent TERT Promoter Mutations in Human Melanoma

(2013) F. W. Huang et al.   SCIENCE

Frequency of TERT promoter mutations in human cancers

(2013) João Vinagre et al.   Nature Communications

Postnatal isoform switch and protein localization of LEF1 and TCF7L2 transcription factors in cortical, thalamic, and mesencephalic regions of the adult mouse brain

(2012) A. Nagalski et al.   Brain Structure & Function

Human Telomerase Reverse Transcriptase (hTERT) Is a Novel Target of the Wnt/β-Catenin Pathway in Human Cancer

(2012) Yong Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Treatment decisions in elderly patients with glioblastoma

(2012) Alba A. Brandes et al.   Nature Reviews Neurology

VHL regulates the effects of miR-23b on glioma survival and invasion via suppression of HIF-1α/VEGF and β-catenin/Tcf-4 signaling

(2012) Lingchao Chen et al.   NEURO-ONCOLOGY

Pioglitazone activates aortic telomerase and prevents stress-induced endothelial apoptosis

(2011) Christian Werner et al.   ATHEROSCLEROSIS

Quantifying the Role of Angiogenesis in Malignant Progression of Gliomas: In Silico Modeling Integrates Imaging and Histology

(2011) K. R. Swanson et al.   CANCER RESEARCH

Wnt signaling and telomerase activation of hepatoblastoma: correlation with chemosensitivity and surgical resectability

(2011) Yuka Ueda et al.   JOURNAL OF PEDIATRIC SURGERY

Annual Report to the Nation on the Status of Cancer, 1975-2007, Featuring Tumors of the Brain and Other Nervous System

(2011) B. A. Kohler et al.   JNCI-Journal of the National Cancer Institute

Clinical correlation of MGMT protein expression and promoter methylation in Chinese glioblastoma patients

(2011) Kai Tang et al.   MEDICAL ONCOLOGY

MGMT promoter methylation is predictive of response to radiotherapy and prognostic in the absence of adjuvant alkylating chemotherapy for glioblastoma

(2011) A. L. Rivera et al.   NEURO-ONCOLOGY

O6-Methylguanine DNA methyltransferase protein expression in tumor cells predicts outcome of temozolomide therapy in glioblastoma patients

(2011) S. Spiegl-Kreinecker et al.   NEURO-ONCOLOGY

O6-methylguanine DNA-methyltransferase methylation status can change between first surgery for newly diagnosed glioblastoma and second surgery for recurrence: clinical implications

(2011) A. A. Brandes et al.   NEURO-ONCOLOGY

siRNA-mediated inhibition of hTERT enhances chemosensitivity of hepatocellular carcinoma

(2010) Xianling Guo et al.   CANCER BIOLOGY & THERAPY

Condition-adapted stress and longevity gene regulation byCaenorhabditis elegansSKN-1/Nrf

(2009) Riva P. Oliveira et al.   AGING CELL

Randomized Phase II Trial of Chemoradiotherapy Followed by Either Dose-Dense or Metronomic Temozolomide for Newly Diagnosed Glioblastoma

(2009) Jennifer L. Clarke et al.   JOURNAL OF CLINICAL ONCOLOGY

Estradiol Activates β-Catenin Dependent Transcription in Neurons

(2009) Olga Varea et al.   PLoS One

Hypoxia-Mediated Induction of the Polyamine System Provides Opportunities for Tumor Growth Inhibition by Combined Targeting of Vascular Endothelial Growth Factor and Ornithine Decarboxylase

(2008) K. J. Svensson et al.   CANCER RESEARCH

Temozolomide Preferentially Depletes Cancer Stem Cells in Glioblastoma

(2008) D. Beier et al.   CANCER RESEARCH

MGMTPromoter Methylation Status Can Predict the Incidence and Outcome of Pseudoprogression After Concomitant Radiochemotherapy in Newly Diagnosed Glioblastoma Patients

(2008) Alba A. Brandes et al.   JOURNAL OF CLINICAL ONCOLOGY