Article
Geriatrics & Gerontology
Yotam Lavy, Tzvi Dwolatzky, Zeev Kaplan, Jonathan Guez, Doron Todder
Summary: The study found that using an EEG-based neurofeedback system can significantly improve memory performance in patients with mild cognitive impairment (MCI), with this improvement lasting for at least one month.
FRONTIERS IN AGING NEUROSCIENCE
(2021)
Article
Psychology, Clinical
Holger C. Bringmann, Andreas Michalsen, Michael Jeitler, Christian S. Kessler, Benno Brinkhaus, Stefan Brunnhuber, Peter Sedlmeier
Summary: This study aimed to investigate the efficacy of the new Meditation-Based Lifestyle Modification (MBLM) program in depressive outpatients. The results showed beneficial effects of MBLM in reducing depressive symptoms. Further high-quality controlled clinical studies, including qualitative research, are needed to explore the specific and unspecific effects of the MBLM program in depression and other medical conditions.
DEPRESSION AND ANXIETY
(2022)
Article
Surgery
Elena Ramirez-Maldonado, Sandra Lopez Gordo, Eva M. Pueyo, Ariadna Sanchez-Garcia, Susana Mayol, Sergio Gonzalez, Jordi Elvira, Robert Memba, Constantino Fondevila, Rosa Jorba
Summary: Immediate oral refeeding in mild and moderate acute pancreatitis significantly reduces hospital length-of-stay and costs compared to conventional oral refeeding, without causing adverse effects or complications.
Article
Hematology
Riten Kumar, Amy L. Dunn, Jane E. Schneiderman, Anne Gonzales, Vanessa Bouskill, Pamela Widener, Joseph Stanek, Fred G. Pluthero, Amanda Waller, Cristina Tarango, Sanjay Ahuja, Bryce A. Kerlin, Walter H. A. Kahr, Margaret L. Rand, David Lillicrap, Manuel Carcao
Summary: Persons with mild hemophilia A can improve their coagulation function by using intranasal desmopressin prior to sports participation, although the duration of improvement is short. Moderate-intensity aerobic exercise can also improve coagulation function. Combining exercise with desmopressin treatment can achieve better results.
Article
Nutrition & Dietetics
T. Yates, J. Henson, P. McBride, B. Maylor, L. Y. Herring, J. A. Sargeant, M. J. Davies, P. C. Dempsey, A. V. Rowlands, C. L. Edwardson
Summary: This study investigates the step cadence values for moderate-intensity walking in older adults during treadmill walking and daily living. The findings suggest that a step cadence of 70 steps/minute may indicate moderate-intensity stepping in older adults.
INTERNATIONAL JOURNAL OF BEHAVIORAL NUTRITION AND PHYSICAL ACTIVITY
(2023)
Article
Chemistry, Medicinal
Maedeh Chegini, Amir Sadeghi, Farid Zaeri, Majid Zamani, Azita Hekmatdoost
Summary: This study investigated the effectiveness of nano-curcumin as an anti-inflammatory agent in patients with mild and moderate acute pancreatitis (AP). It was a double-blind, parallel-arm randomized controlled trial conducted in Tehran, Iran. The results showed that nano-curcumin supplementation reduced hospital length of stay, decreased the need for analgesics, and improved overall appetite in patients with AP. No adverse effects or mortality were reported. Further larger-scale multi-center trials are needed to confirm these findings.
PHYTOTHERAPY RESEARCH
(2023)
Article
Medicine, General & Internal
Jiayu Zhang, Xu Kuang, Chunzhi Tang, Nenggui Xu, Songhua Xiao, Lingjun Xiao, Shengwen Wang, Yu Dong, Liming Lu, Liang Zhang
Summary: This pilot multicenter trial aims to evaluate the effectiveness and safety of acupuncture on aMCI, as well as explore the feasibility of acupuncture in treating aMCI. The trial will include 50 eligible patients who will be randomly allocated to acupuncture group or sham acupuncture group for 12 weeks of treatment.
Article
Neurosciences
Oluwole O. Awosika, Dorothy Chan, Heidi J. Sucharew, Pierce Boyne, Amit Bhattacharya, Kari Dunning, Brett M. Kissela
Summary: The study investigated the effectiveness of backward locomotor treadmill training on post-stroke walking impairment patients and found that this training approach is safe and beneficial regardless of the severity of walking impairment in patients.
Article
Biochemistry & Molecular Biology
Catherine J. Mummery, Anne Borjesson-Hanson, Daniel J. Blackburn, Everard G. B. Vijverberg, Peter Paul De Deyn, Simon Ducharme, Michael Jonsson, Anja Schneider, Juha O. Rinne, Albert C. Ludolph, Ralf Bodenschatz, Holly Kordasiewicz, Eric E. Swayze, Bethany Fitzsimmons, Laurence Mignon, Katrina M. Moore, Chris Yun, Tiffany Baumann, Dan Li, Daniel A. Norris, Rebecca Crean, Danielle L. Graham, Ellen Huang, Elena Ratti, C. Frank Bennett, Candice Junge, Roger M. Lane
Summary: By inhibiting MAPT expression with a tau-targeting antisense oligonucleotide (MAPTRx), researchers were able to reduce tau levels in patients with mild Alzheimer's disease. A randomized, double-blind trial found that the CSF total-tau protein concentration decreased by more than 50% in patients treated with MAPTRx, with mild adverse effects reported.
Article
Clinical Neurology
Saily Sosa, Giosmany Bringas, Nelky Urrutia, Ana Ivis Penalver, Danay Lopez, Evelio Gonzalez, Ana Fernandez, Zenaida Milagros Hernandez, Ariel Vina, Yamile Pena, Juan Felipe Batista, Carmen Valenzuela, Kalet Leon, Tania Crombet, Teresita Rodriguez, Leslie Perez
Summary: NeuroEPO plus improves cognitive evaluation in patients with mild to moderate Alzheimer's disease, with a good safety profile.
ALZHEIMERS RESEARCH & THERAPY
(2023)
Article
Multidisciplinary Sciences
Rajan Ravichandran, Surapaneni Krishna Mohan, Suresh Kumar Sukumaran, Devakumar Kamaraj, Sumetha Suga Daivasuga, Samson Oliver Abraham Samuel Ravi, Sivakumar Vijayaraghavalu, Ramarathnam Krishna Kumar
Summary: This randomized clinical trial in a hospital setting evaluated the efficacy and safety of indomethacin in COVID-19 patients. The results showed that indomethacin can effectively relieve symptoms, reduce the risk of hypoxia, and had no reported adverse events.
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
Yehudit Bloch, R. H. Belmaker, Pesach Shvartzman, Pnina Romem, Arkady Bolotin, Yuly Bersudsky, Abed N. Azab
Summary: This study demonstrates that normobaric oxygen treatment has a significant therapeutic effect on symptoms of depression, particularly in improving HRSD and CGI scores.
SCIENTIFIC REPORTS
(2021)
Article
Immunology
Yoav Golan, Jesus Abraham Simon Campos, Rob Woolson, Donald Cilla, Rodolfo Hanabergh, Yaneicy Gonzales-Rojas, Reynaldo Lopez, Robert Finberg, Armand Balboni
Summary: This double-blind randomized controlled trial demonstrates that favipiravir is not effective in mitigating COVID-19 symptoms, preventing disease progression, and stopping viral shedding.
CLINICAL INFECTIOUS DISEASES
(2023)
Article
Medicine, General & Internal
Joon-Young Song, Jin-Gu Yoon, Yu-Bin Seo, Jacob Lee, Joong-Sik Eom, Jin-Soo Lee, Won-Suk Choi, Eun-Young Lee, Young-Ah Choi, Hak-Jun Hyun, Hye Seong, Ji-Yun Noh, Hee-Jin Cheong, Woo-Joo Kim
Summary: The ciclesonide inhalation treatment significantly increased the SARS-CoV-2 eradication rate and reduced the clinical failure rate in patients with mild-to-moderate COVID-19, suggesting its potential efficacy in managing the disease.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Medicine, General & Internal
Yan Press, Boris Punchik, Ella Kagan, Alexander Berzak, Tamar Freud, Tzvi Dwolatzky
Summary: In this exploratory study evaluating the effects of methylphenidate (MPH) on cognitive function in older patients with mild cognitive impairment (MCI), it was found that MPH had a modest beneficial effect on memory, particularly non-verbal memory. Despite the occurrence of 12 adverse events, they were all rated as mild to moderate, indicating a generally tolerable safety profile for MPH in this population. Further research is needed to investigate the potential benefits of MPH in this population.
FRONTIERS IN MEDICINE
(2021)
Article
Physiology
A. C. Coelho, D. T. Cannon, R. Cao, J. Porszasz, R. Casaburi, M. M. Knorst, H. B. Rossiter
JOURNAL OF APPLIED PHYSIOLOGY
(2015)
Article
Nutrition & Dietetics
Joel D. Kopple, Jun C. Kim, Bryan B. Shapiro, Min Zhang, Yinan Li, Janos Porszasz, Rachelle Bross, Usama Feroze, Rajeev Upreti, Kamyar Kalantar-Zadeh
JOURNAL OF RENAL NUTRITION
(2015)
Article
Critical Care Medicine
Asli Gorek Dilektasli, Janos Porszasz, Richard Casaburi, William W. Stringer, Surya P. Bhatt, Youngju Pak, Harry B. Rossiter, George Washko, Peter J. Castaldi, Raul San Jose Estepar, James E. Hansen
Article
Respiratory System
Luis Puente-Maestu, Paolo Palange, Richard Casaburi, Pierantonio Laveneziana, Francois Maltais, J. Alberto Neder, Denis E. O'Donnell, Paolo Onorati, Janos Porszasz, Roberto Rabinovich, Harry B. Rossiter, Sally Singh, Thierry Troosters, Susan Ward
EUROPEAN RESPIRATORY JOURNAL
(2016)
Article
Physiology
Daniel T. Cannon, Ana Claudia Coelho, Robert Cao, Andrew Cheng, Janos Porszasz, Richard Casaburi, Harry B. Rossiter
JOURNAL OF APPLIED PHYSIOLOGY
(2016)
Article
Physiology
Janos Varga, Richard Casaburi, Shuyi Ma, Ariel Hecht, David Hsia, Attila Somfay, Janos Porszasz
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2016)
Article
Respiratory System
Janos Porszasz, Susan Blonshine, Robert Cao, Heather A. Paden, Richard Casaburi, Harry B. Rossiter
BMC PULMONARY MEDICINE
(2016)
Article
Physiology
Alessandra Adami, Robert Cao, Janos Porszasz, Richard Casaburi, Harry B. Rossiter
RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
(2017)
Editorial Material
Critical Care Medicine
James E. Hansen, Janos Porszasz
Editorial Material
Critical Care Medicine
James E. Hansen, Janos Porszasz
Article
Respiratory System
Hester van der Vaart, Scott R. Murgatroyd, Harry B. Rossiter, Carey Chen, Richard Casaburi, Janos Porszasz
COPD-JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE
(2014)
Article
Nutrition & Dietetics
Min Zhang, Jun Chul Kim, Yinan Li, Bryan B. Shapiro, Janos Porszasz, Rachelle Bross, Usama Feroze, Rajeev Upreti, David Martin, Kamyar Kalantar-Zadeh, Joel D. Kopple
JOURNAL OF RENAL NUTRITION
(2014)
Article
Health Care Sciences & Services
Kristen E. Holm, Richard Casaburi, Scott Cerreta, Helene A. Gussin, Julian Husbands, Janos Porszasz, Valentin Prieto-Centurion, Robert A. Sandhaus, Jamie L. Sullivan, Linda J. Walsh, Jerry A. Krishnan
PATIENT-PATIENT CENTERED OUTCOMES RESEARCH
(2016)
Article
Respiratory System
Jin Hwa Lee, Michael H. Cho, Craig P. Hersh, Merry-Lynn N. McDonald, James D. Crapo, Per S. Bakke, Amund Gulsvik, Alejandro P. Comellas, Christine H. Wendt, David A. Lomas, Victor Kim, Edwin K. Silverman
RESPIRATORY RESEARCH
(2014)