Evaluation of Influence of Single Nucleotide Polymorphisms in Cytochrome P450 2B6 on Substrate Recognition Using Computational Docking and Molecular Dynamics Simulation

Subtle Structural Changes in Tetrahydroquinolines, A New Class of Nonsteroidal Selective Androgen Receptor Modulators, Induce Different Functions

(2012) Naoya Nagata et al.   Journal of Chemical Information and Modeling

Functional Characterization of CYP2B6 Allelic Variants in Demethylation of Antimalarial Artemether

(2011) M. Honda et al.   DRUG METABOLISM AND DISPOSITION

Analysis of clinically relevant substrates of CYP2B6 enzyme by computational methods

(2011) Rui-Juan Niu et al.   JOURNAL OF MOLECULAR MODELING

Pharmacokinetics of artemether and dihydroartemisinin in healthy Pakistani male volunteers treated with artemether-lumefantrine

(2010) Shabana Ali et al.   MALARIA JOURNAL

Crystal Structure of a Cytochrome P450 2B6 Genetic Variant in Complex with the Inhibitor 4-(4-Chlorophenyl)imidazole at 2.0-A Resolution

(2010) S. C. Gay et al.   MOLECULAR PHARMACOLOGY

Evaluation of the searching abilities of HBOP and HBSITE for binding pocket detection

(2009) Akifumi Oda et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Determination of Ligand-Binding Sites on Proteins Using Long-Range Hydrophobic Potential

(2008) Noriyuki Yamaotsu et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Application of Molecular Modeling for Prediction of Substrate Specificity in Cytochrome P450 1A2 Mutants

(2008) Y. Tu et al.   DRUG METABOLISM AND DISPOSITION

Flexibility of Human Cytochromes P450: Molecular Dynamics Reveals Differences between CYPs 3A4, 2C9, and 2A6, which Correlate with Their Substrate Preferences

(2008) Josef Skopalík et al.   JOURNAL OF PHYSICAL CHEMISTRY B