Novel Anti-Apoptotic MicroRNAs 582-5p and 363 Promote Human Glioblastoma Stem Cell Survival via Direct Inhibition of Caspase 3, Caspase 9, and Bim

The c-Myc-Regulated MicroRNA-17∼92 (miR-17∼92) and miR-106a∼363 Clusters Target hCYP19A1 and hGCM1 To Inhibit Human Trophoblast Differentiation

(2013) Premlata Kumar et al.   MOLECULAR AND CELLULAR BIOLOGY

MiR-219-5p inhibits hepatocellular carcinoma cell proliferation by targeting glypican-3

(2012) Na Huang et al.   FEBS LETTERS

Genome-Wide Profiling Identified a Set of miRNAs that Are Differentially Expressed in Glioblastoma Stem Cells and Normal Neural Stem Cells

(2012) Ming-Fei Lang et al.   PLoS One

Enforced Expression of miR-101 Inhibits Prostate Cancer Cell Growth by Modulating the COX-2 PathwayIn Vivo

(2011) Yubin Hao et al.   Cancer Prevention Research

A Developmental Taxonomy of Glioblastoma Defined and Maintained by MicroRNAs

(2011) T.-M. Kim et al.   CANCER RESEARCH

MicroRNA Replacement Therapy for miR-145 and miR-33a Is Efficacious in a Model of Colon Carcinoma

(2011) A. F. Ibrahim et al.   CANCER RESEARCH

Programmed Cell Death in Animal Development and Disease

(2011) Yaron Fuchs et al.   CELL

MiR-129-5p is required for histone deacetylase inhibitor-induced cell death in thyroid cancer cells

(2011) Patrick Brest et al.   ENDOCRINE-RELATED CANCER

The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44

(2011) Can Liu et al.   NATURE MEDICINE

NF-kB and c-Jun induce the expression of the oncogenic miR-221 and miR-222 in prostate carcinoma and glioblastoma cells

(2011) S. Galardi et al.   NUCLEIC ACIDS RESEARCH

A CD133-related gene expression signature identifies an aggressive glioblastoma subtype with excessive mutations

(2011) X. Yan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

C6-ceramide synergistically potentiates the anti-tumor effects of histone deacetylase inhibitors via AKT dephosphorylation and α-tubulin hyperacetylation both in vitro and in vivo

(2011) Q-y Zhu et al.   Cell Death & Disease

Regulation of mRNA Translation and Stability by microRNAs

(2010) Marc Robert Fabian et al.   Annual Review of Biochemistry

Bone morphogenetic protein-7 release from endogenous neural precursor cells suppresses the tumourigenicity of stem-like glioblastoma cells

(2010) Sridhar Reddy Chirasani et al.   BRAIN

MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity

(2010) Lei Shi et al.   BRAIN RESEARCH

MiR-146b-5p Suppresses EGFR Expression and ReducesIn VitroMigration and Invasion of Glioma

(2010) Mark Katakowski et al.   CANCER INVESTIGATION

Oncogenic Role of miR-483-3p at the IGF2/483 Locus

(2010) A. Veronese et al.   CANCER RESEARCH

microRNA-34a is tumor suppressive in brain tumors and glioma stem cells

(2010) Fadila Guessous et al.   CELL CYCLE

Differentiation Therapy Exerts Antitumor Effects on Stem-like Glioma Cells

(2010) B. Campos et al.   CLINICAL CANCER RESEARCH

Targeting miR-21 in glioma: a small RNA with big potential

(2010) Lynette M Moore et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Co-delivery of as-miR-21 and 5-FU by Poly(amidoamine) Dendrimer Attenuates Human Glioma Cell Growth in Vitro

(2010) Yu Ren et al.   JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

The elephant in the room: do microRNA-based therapies have a realistic chance of succeeding for brain tumors such as glioblastoma?

(2010) Benjamin Purow   JOURNAL OF NEURO-ONCOLOGY

MiR-221 and miR-222 target PUMA to induce cell survival in glioblastoma

(2010) Chun-Zhi Zhang et al.   Molecular Cancer

Overexpression of CD133 Promotes Drug Resistance in C6 Glioma Cells

(2010) J. M. Angelastro et al.   MOLECULAR CANCER RESEARCH

“Where, O Death, Is Thy Sting?” A Brief Review of Apoptosis Biology

(2010) Andrew H. Wyllie   MOLECULAR NEUROBIOLOGY

miR-34a confers chemosensitivity through modulation of MAGE-A and p53 in medulloblastoma

(2010) Shyamal D. Weeraratne et al.   NEURO-ONCOLOGY

Pyruvate kinase M2 is a target of the tumor-suppressive microRNA-326 and regulates the survival of glioma cells

(2010) B. Kefas et al.   NEURO-ONCOLOGY

De-repression of CTGF via the miR-17-92 cluster upon differentiation of human glioblastoma spheroid cultures

(2010) A Ernst et al.   ONCOGENE

AP-1-Dependent miR-21 Expression Contributes to Chemoresistance in Cancer Stem Cell-Like SP Cells

(2010) Aya Misawa et al.   ONCOLOGY RESEARCH

MicroRNA profile indicates downregulation of the TGFβ pathway in sporadic non-functioning pituitary adenomas

(2010) Henriett Butz et al.   Pituitary

Identification and Functional Characterization of microRNAs Involved in the Malignant Progression of Gliomas

(2009) Bastian Malzkorn et al.   BRAIN PATHOLOGY

MicroRNA-34a Inhibits Glioblastoma Growth by Targeting Multiple Oncogenes

(2009) Y. Li et al.   CANCER RESEARCH

MicroRNAs and glioblastoma; the stem cell connection

(2009) J Godlewski et al.   CELL DEATH AND DIFFERENTIATION

Genomic and Expression Profiling of Glioblastoma Stem Cell-Like Spheroid Cultures Identifies Novel Tumor-Relevant Genes Associated with Survival

(2009) A. Ernst et al.   CLINICAL CANCER RESEARCH

MiR-128 up-regulation inhibits Reelin and DCX expression and reduces neuroblastoma cell motility and invasiveness

(2009) Cristina Evangelisti et al.   FASEB JOURNAL

The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo

(2009) J. T. Huse et al.   GENES & DEVELOPMENT

Molecular properties of CD133+ glioblastoma stem cells derived from treatment-refractory recurrent brain tumors

(2009) Qinghai Liu et al.   JOURNAL OF NEURO-ONCOLOGY

The Neuronal MicroRNA miR-326 Acts in a Feedback Loop with Notch and Has Therapeutic Potential against Brain Tumors

(2009) B. Kefas et al.   JOURNAL OF NEUROSCIENCE

High miR-196a levels promote the oncogenic phenotype of colorectal cancer cells

(2009) Carl Christoph Schimanski et al.   WORLD JOURNAL OF GASTROENTEROLOGY

miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells

(2008) Joachim Silber et al.   BMC Medicine

CD133 Expression and Cancer Stem Cells Predict Prognosis in High-grade Oligodendroglial Tumors

(2008) Dagmar Beier et al.   BRAIN PATHOLOGY

microRNA-7 Inhibits the Epidermal Growth Factor Receptor and the Akt Pathway and Is Down-regulated in Glioblastoma

(2008) B. Kefas et al.   CANCER RESEARCH

Targeting of the Bmi-1 Oncogene/Stem Cell Renewal Factor by MicroRNA-128 Inhibits Glioma Proliferation and Self-Renewal

(2008) J. Godlewski et al.   CANCER RESEARCH

Notch-1 regulates transcription of the epidermal growth factor receptor through p53

(2008) Benjamin W. Purow et al.   CARCINOGENESIS

Apomab: An agonist monoclonal antibody directed against Death Receptor 5/TRAIL-Receptor 2 for use in the treatment of solid tumors

(2008) D Ross Camidge   EXPERT OPINION ON BIOLOGICAL THERAPY

Regulation of microRNA processing in development, differentiation and cancer

(2008) Thomas D. Schmittgen   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Brain tumour stem cells: the undercurrents of human brain cancer and their relationship to neural stem cells

(2007) P. B Dirks   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES