Interleukin-7 and Toll-Like Receptor 7 Induce Synergistic B Cell and T Cell Activation

Increased interleukin (IL)-7Rα expression in salivary glands of patients with primary Sjögren's syndrome is restricted to T cells and correlates with IL-7 expression, lymphocyte numbers and activity

(2012) A Bikker et al.   ANNALS OF THE RHEUMATIC DISEASES

Prevalence of interferon type I signature in CD14 monocytes of patients with Sjögren's syndrome and association with disease activity and BAFF gene expression

(2012) Zana Brkic et al.   ANNALS OF THE RHEUMATIC DISEASES

Role of toll-like receptors in primary Sjögren’s syndrome with a special emphasis on B-cell maturation within exocrine tissues

(2012) Thomas Guerrier et al.   JOURNAL OF AUTOIMMUNITY

IL-7 modulates B cells survival and activation by inducing BAFF and CD70 expression in T cells

(2012) Stefano Sammicheli et al.   JOURNAL OF AUTOIMMUNITY

IL-7-activated T cells and monocytes drive B cell activation in patients with primary Sjogren's syndrome

(2011) A. Bikker et al.   ANNALS OF THE RHEUMATIC DISEASES

An update on an immune system that goes awry in systemic sclerosis

(2011) L. van Bon et al.   CURRENT OPINION IN RHEUMATOLOGY

Decrease in immunoglobulin free light chains in patients with rheumatoid arthritis upon rituximab (anti-CD20) treatment correlates with decrease in disease activity

(2010) T. G. Kormelink et al.   ANNALS OF THE RHEUMATIC DISEASES

Increased expression of interleukin-7 in labial salivary glands of patients with primary Sjögren's syndrome correlates with increased inflammation

(2010) A. Bikker et al.   ARTHRITIS AND RHEUMATISM

Blockade of the interleukin-7 receptor inhibits collagen-induced arthritis and is associated with reduction of T cell activity and proinflammatory mediators

(2010) Sarita A. Y. Hartgring et al.   ARTHRITIS AND RHEUMATISM

Salivary epithelial cells from Sjogren’s syndrome patients are highly sensitive to anoikis induced by TLR-3 ligation

(2010) Menelaos N. Manoussakis et al.   JOURNAL OF AUTOIMMUNITY

Alternative splicing of interleukin-7 (IL-7) and interleukin-7 receptor alpha (IL-7Rα) in peripheral blood from patients with multiple sclerosis (MS)

(2010) Lalit Rane et al.   JOURNAL OF NEUROIMMUNOLOGY

Expression of Toll-like receptors 7, 8, and 9 in primary Sjögren's syndrome

(2010) Lingyan Zheng et al.   ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS

Numbers of CD25+Foxp3+ T cells that lack the IL-7 receptor are increased intra-articularly and have impaired suppressive function in RA patients

(2010) J. A. G. van Roon et al.   RHEUMATOLOGY

Elevated expression of interleukin-7 receptor in inflamed joints mediates interleukin-7-induced immune activation in rheumatoid arthritis

(2009) Sarita A. Y. Hartgring et al.   ARTHRITIS AND RHEUMATISM

Regulation of autoreactive B cell responses to endogenous TLR ligands

(2009) Ana Maria Avalos et al.   AUTOIMMUNITY

Characteristics of the minor salivary gland infiltrates in Sjögren's syndrome

(2009) Maria I. Christodoulou et al.   JOURNAL OF AUTOIMMUNITY

Cutting Edge: Importance of IL-6 and Cooperation between Innate and Adaptive Immune Receptors in Cellular Vaccination with B Lymphocytes

(2009) T. J. Vanden Bush et al.   JOURNAL OF IMMUNOLOGY

Toll-like receptor 7 cooperates with IL-4 in activated B cells through antigen receptor or CD38 and induces class switch recombination and IgG1 production

(2009) Yumiko Tsukamoto et al.   MOLECULAR IMMUNOLOGY

Increased frequency of CD16+ monocytes and the presence of activated dendritic cells in salivary glands in primary Sjogren syndrome

(2008) M E Wildenberg et al.   ANNALS OF THE RHEUMATIC DISEASES

Cytokines secreted in response to Toll-like receptor ligand stimulation modulate differentiation of human Th17 cells

(2008) Michael G. Kattah et al.   ARTHRITIS AND RHEUMATISM

Identification of interleukin-7 as a candidate disease mediator in spondylarthritis

(2008) Markus Rihl et al.   ARTHRITIS AND RHEUMATISM

TLR7 and CD40 cooperate in IL-6 productionviaenhanced JNK and AP-1 activation

(2008) Tony J. Vanden Bush et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Role of mucosal dendritic cells in inflammatory bowel disease

(2008) Jan Hendrik Niess   WORLD JOURNAL OF GASTROENTEROLOGY