Matrix Metalloproteinase-9 Is Involved in Chronic Lymphocytic Leukemia Cell Response to Fludarabine and Arsenic Trioxide

Chronic lymphocytic leukemia: 2013 update on diagnosis, risk stratification and treatment

(2013) Michael Hallek   AMERICAN JOURNAL OF HEMATOLOGY

Chronic lymphocytic leukaemia - the role of the microenvironment pathogenesis and therapy

(2013) Alan D. Ramsay et al.   BRITISH JOURNAL OF HAEMATOLOGY

Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9): The next decade

(2013) Jennifer Vandooren et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Improving the Treatment Outcome of Patients with Chronic Lymphocytic Leukemia Through Targeted Antibody Therapy

(2013) Deborah M. Stephens et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy

(2013) Peter E. Czabotar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The microenvironment in chronic lymphocytic leukemia (CLL) and other B cell malignancies: Insight into disease biology and new targeted therapies

(2013) Jan A. Burger et al.   SEMINARS IN CANCER BIOLOGY

BECN1 and BIM interactions with MCL-1 determine fludarabine resistance in leukemic B cells

(2013) A Sharma et al.   Cell Death & Disease

Targeting the microenvironment in chronic lymphocytic leukemia is changing the therapeutic landscape

(2012) Jan A. Burger   CURRENT OPINION IN ONCOLOGY

Molecular pathogenesis of chronic lymphocytic leukemia

(2012) Gianluca Gaidano et al.   JOURNAL OF CLINICAL INVESTIGATION

How to manage acute promyelocytic leukemia

(2012) J-Q Mi et al.   LEUKEMIA

Downregulation of Mcl-1 through GSK-3β activation contributes to arsenic trioxide-induced apoptosis in acute myeloid leukemia cells

(2012) R Wang et al.   LEUKEMIA

Host Response to Short-term, Single-Agent Chemotherapy Induces Matrix Metalloproteinase-9 Expression and Accelerates Metastasis in Mice

(2011) S. Gingis-Velitski et al.   CANCER RESEARCH

Spleen tyrosine kinase inhibition prevents chemokine- and integrin-mediated stromal protective effects in chronic lymphocytic leukemia

(2010) M. Buchner et al.   BLOOD

Matrix Metalloproteinase-9 Promotes Chronic Lymphocytic Leukemia B Cell Survival through Its Hemopexin Domain

(2010) Javier Redondo-Muñoz et al.   CANCER CELL

Induction of B-Chronic Lymphocytic Leukemia Cell Apoptosis by Arsenic Trioxide Involves Suppression of the Phosphoinositide 3-Kinase/Akt Survival Pathway via c-jun-NH2 Terminal Kinase Activation and PTEN Upregulation

(2010) J. Redondo-Munoz et al.   CLINICAL CANCER RESEARCH

Correlation analysis of intracellular and secreted cytokines via the generalized integrated mean fluorescence intensity

(2010) Parisa Shooshtari et al.   CYTOMETRY PART A

L718P mutation in the membrane-proximal cytoplasmic tail of  3 promotes abnormal  IIb 3 clustering and lipid microdomain coalescence, and associates with a thrombasthenia-like phenotype

(2010) A. Jayo et al.   HAEMATOLOGICA

Urokinase Plasminogen Activator Receptor and/or Matrix Metalloproteinase-9 Inhibition Induces Apoptosis Signaling through Lipid Rafts in Glioblastoma Xenograft Cells

(2010) C. Chetty et al.   MOLECULAR CANCER THERAPEUTICS

Molecular and cellular mechanisms of CLL: novel therapeutic approaches

(2009) Lisa Pleyer et al.   Nature Reviews Clinical Oncology

Mcl-1: the 1 in CLL

(2008) V. Gandhi et al.   BLOOD

BH3-only proteins Noxa, Bmf, and Bim are necessary for arsenic trioxide-induced cell death in myeloma

(2008) A. A. Morales et al.   BLOOD

Targeting MEK/MAPK signal transduction module potentiates ATO-induced apoptosis in multiple myeloma cells through multiple signaling pathways

(2008) P. Lunghi et al.   BLOOD

 4 1 integrin and 190-kDa CD44v constitute a cell surface docking complex for gelatinase B/MMP-9 in chronic leukemic but not in normal B cells

(2008) J. Redondo-Munoz et al.   BLOOD

AT-101 induces apoptosis in CLL B cells and overcomes stromal cell-mediated Mcl-1 induction and drug resistance

(2008) K. Balakrishnan et al.   BLOOD

Acute promyelocytic leukemia: from highly fatal to highly curable

(2008) Z.-Y. Wang et al.   BLOOD

Arsenic trioxide induces apoptosis preferentially in B-CLL cells of patients with unfavourable prognostic factors including del17p13

(2008) Olaf Merkel et al.   JOURNAL OF MOLECULAR MEDICINE-JMM