Bacterial Peptidoglycan Stimulates Adipocyte Lipolysis via NOD1

Activation of nucleotide oligomerization domain containing protein 1 induces lipolysis through NF-κB and the lipolytic PKA activation in 3T3-L1 adipocytes

(2013) Jaanki S. Purohit et al.   Biochemistry and Cell Biology

Identification of Benzimidazole Diamides as Selective Inhibitors of the Nucleotide-Binding Oligomerization Domain 2 (NOD2) Signaling Pathway

(2013) David J. Rickard et al.   PLoS One

Partial Inhibition of Adipose Tissue Lipolysis Improves Glucose Metabolism and Insulin Sensitivity Without Alteration of Fat Mass

(2013) Amandine Girousse et al.   PLOS BIOLOGY

Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance

(2012) Durba Pal et al.   NATURE MEDICINE

Regulation of NF-κB Activation through a Novel PI-3K-Independent and PKA/Akt-Dependent Pathway in Human Umbilical Vein Endothelial Cells

(2012) Sakshi Balwani et al.   PLoS One

Immuno-microbiota cross and talk: The new paradigm of metabolic diseases

(2012) Rémy Burcelin et al.   SEMINARS IN IMMUNOLOGY

NOD1 activation induces proinflammatory gene expression and insulin resistance in 3T3-L1 adipocytes

(2011) Ling Zhao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Give a NOD to insulin resistance

(2011) Jonathan D. Schertzer et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Discovery and Characterization of 2-Aminobenzimidazole Derivatives as Selective NOD1 Inhibitors

(2011) Ricardo G. Correa et al.   CHEMISTRY & BIOLOGY

NOD1 Activators Link Innate Immunity to Insulin Resistance

(2011) J. D. Schertzer et al.   DIABETES

Involvement of tissue bacteria in the onset of diabetes in humans: evidence for a concept

(2011) J. Amar et al.   DIABETOLOGIA

Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment

(2011) Jacques Amar et al.   EMBO Molecular Medicine

Non-apoptotic role of BID in inflammation and innate immunity

(2011) Garabet Yeretssian et al.   NATURE

Fatty acid–induced NLRP3-ASC inflammasome activation interferes with insulin signaling

(2011) Haitao Wen et al.   NATURE IMMUNOLOGY

Identification of Inhibitors of NOD1-Induced Nuclear Factor-κB Activation

(2011) Pasha M. Khan et al.   ACS Medicinal Chemistry Letters

β3-adrenergic receptor induction of adipocyte inflammation requires lipolytic activation of stress kinases p38 and JNK

(2010) Emilio P. Mottillo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Double-Stranded RNA-Dependent Protein Kinase Links Pathogen Sensing with Stress and Metabolic Homeostasis

(2010) Takahisa Nakamura et al.   CELL

NOD2 Activation Induces Muscle Cell-Autonomous Innate Immune Responses and Insulin Resistance

(2010) Akhilesh K. Tamrakar et al.   ENDOCRINOLOGY

Both inflammatory and classical lipolytic pathways are involved in lipopolysaccharide-induced lipolysis in human adipocytes

(2010) Jean Grisouard et al.   Innate Immunity

Whole Body Deletion of AMP-activated Protein Kinase β2 Reduces Muscle AMPK Activity and Exercise Capacity

(2010) Gregory R. Steinberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway

(2010) Tomohiro Watanabe et al.   JOURNAL OF CLINICAL INVESTIGATION

Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity

(2010) Thomas B Clarke et al.   NATURE MEDICINE

Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability

(2009) P. D. Cani et al.   GUT

Bacterial Endotoxin Stimulates Adipose Lipolysis via Toll-Like Receptor 4 and Extracellular Signal-regulated Kinase Pathway

(2009) Luxia Zu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fat Talks, Liver and Muscle Listen

(2008) Jerrold M. Olefsky   CELL

Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet-Induced Obesity and Diabetes in Mice

(2008) P. D. Cani et al.   DIABETES

Nod-like proteins in inflammation and disease

(2007) LAM Carneiro et al.   JOURNAL OF PATHOLOGY