Opposing Effects of PI3K/Akt and Smad-Dependent Signaling Pathways in NAG-1-Induced Glioblastoma Cell Apoptosis

A Novel Benzothiazole Derivative YLT322 Induces Apoptosis via the Mitochondrial Apoptosis Pathway In Vitro with Anti-Tumor Activity in Solid Malignancies

(2013) Song Xuejiao et al.   PLoS One

Adaptive Induction of Growth Differentiation Factor 15 Attenuates Endothelial Cell Apoptosis in Response to High Glucose Stimulus

(2013) Jun Li et al.   PLoS One

Targeting the PI3K/AKT/mTOR signaling pathway in glioblastoma: novel therapeutic agents and advances in understanding

(2013) Arshawn Sami et al.   TUMOR BIOLOGY

The diverse roles of nonsteroidal anti-inflammatory drug activated gene (NAG-1/GDF15) in cancer

(2012) Xingya Wang et al.   BIOCHEMICAL PHARMACOLOGY

Phospho-specific Smad3 signaling

(2012) Elizabeth Tarasewicz et al.   CELL CYCLE

Macrophage Inhibitory Cytokine-1 (MIC-1/GDF15) Slows Cancer Development but Increases Metastases in TRAMP Prostate Cancer Prone Mice

(2012) Yasmin Husaini et al.   PLoS One

DNA methylation-mediated silencing of nonsteroidal anti-inflammatory drug-activated gene (NAG-1/GDF15) in glioma cell lines

(2011) Mitsutoshi Kadowaki et al.   INTERNATIONAL JOURNAL OF CANCER

Divergent molecular mechanisms underlying the pleiotropic functions of macrophage inhibitory cytokine-1 in cancer

(2010) Murielle Mimeault et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Targeting Mitochondrial Cell Death Pathway to Overcome Drug Resistance with a Newly Developed Iron Chelate

(2010) Avishek Ganguly et al.   PLoS One

Macrophage Inhibitory Cytokine 1: A New Prognostic Marker in Prostate Cancer

(2009) D. A. Brown et al.   CLINICAL CANCER RESEARCH

Elevated levels of MIC-1/GDF15 in the cerebrospinal fluid of patients are associated with glioblastoma and worse outcome

(2009) Sophie Shnaper et al.   INTERNATIONAL JOURNAL OF CANCER

Expression and putative functions of GDF-15, a member of the TGF-β superfamily, in human glioma and glioblastoma cell lines

(2008) Jens Strelau et al.   CANCER LETTERS

Macrophage inhibitory cytokine-1 activates AKT and ERK-1/2 via the transactivation of ErbB2 in human breast and gastric cancer cells

(2008) Kwang-Kyu Kim et al.   CARCINOGENESIS