Article
Dentistry, Oral Surgery & Medicine
Piero Papi, Nicola Pranno, Bianca Di Murro, Giorgio Pompa, Antonella Polimeni, Claudio Letizia, Luigi Petramala, Antonio Concistre, Eva Munoz Aguilera, Marco Orlandi, Francesco D'Aiuto
Summary: This cross-sectional study investigated the association between carotid intima-media thickness (c-IMT) values and periodontal and peri-implant diseases in patients with hypertension. The study found a positive association between mucosal/gingival inflammation and subclinical atherosclerosis, as well as the presence of carotid plaque. These associations were independent of traditional cardiovascular risk factors.
JOURNAL OF PERIODONTOLOGY
(2023)
Article
Anesthesiology
Tak Kyu Oh, In-Ae Song
Summary: The study found that socioeconomic factors, such as occupation and household income level, are associated with the treatment of patients with low back pain and/or neck pain. Healthcare workers and unemployed individuals were more likely to use chronic opioids, while other workers and unemployed individuals had a higher likelihood of undergoing interventional procedures. Patients with low household incomes had a higher likelihood of using chronic opioids, while those with middle, high, and very poor household incomes were more likely to undergo interventional procedures.
REGIONAL ANESTHESIA AND PAIN MEDICINE
(2023)
Article
Environmental Sciences
Manthar Ali Mallah, Li Changxing, Mukhtiar Ali Mallah, Muhammad Naveed, Yang Liu, Sobia Noreen, He Xi, Wei Wang, Feifei Feng, Qiao Zhang
Summary: This study aimed to investigate the association between urinary PAHs and cardiovascular diseases. The results showed a positive correlation between urinary PAHs and the prevalence of coronary heart disease, angina, heart attack, and stroke.
ENVIRONMENTAL RESEARCH
(2022)
Article
Pediatrics
Aina M. Galmes-Panades, Josep Vidal-Conti
Summary: This study analyzed the relationship between physical fitness and the occurrence and intensity of low back pain. The results showed that higher levels of cardiorespiratory fitness and more physical activity were associated with lower intensity and prevalence of low back pain.
Article
Rehabilitation
Matthias Poesl, Gabriela F. Carvalho, Waclaw M. Adamczyk, Beate Schuessler, Michael Richter, Kerstin Luedtke, Tibor M. Szikszay
Summary: This study aims to investigate whether proprioceptive accuracy measured with the Joint Position Sense (JPS) in patients with chronic neck and low back pain is impaired exclusively in affected areas or also in distant areas not affected by pain.
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION
(2023)
Article
Clinical Neurology
Kana Horibe, Tsunenori Isa, Naoka Matsuda, Shunsuke Murata, Yamato Tsuboi, Maho Okumura, Rika Kawaharada, Masahumi Kogaki, Kazuaki Uchida, Kiyomasa Nakatsuka, Rei Ono
Summary: The study found a significant association between persistent LBPP and sleep disturbance, with a majority of persistent LBPP patients reporting sleep disturbance.
EUROPEAN SPINE JOURNAL
(2021)
Article
Multidisciplinary Sciences
Md. Merajul Islam, Md. Jahangir Alam, Md Maniruzzaman, N. A. M. Faisal Ahmed, Md Sujan Ali, Md. Jahanur Rahman, Dulal Chandra Roy
Summary: This study developed a machine learning system to predict the risk of developing hypertension in Ethiopian patients and identified the associated predictive factors.
Article
Nutrition & Dietetics
Jorge Subias-Perie, David Navarrete-Villanueva, Angel Ivan Fernandez-Garcia, Ana Moradell, Eva Gesteiro, Jorge Perez-Gomez, Ignacio Ara, German Vicente-Rodriguez, Jose Antonio Casajus, Alba Gomez-Cabello
Summary: Metabolic syndrome has a high prevalence in Spanish older adults, but varies with different definitions. Sex and frailty do not appear to influence the development of MetS. However, physical activity seems to decrease the risk of central obesity, hypertension, and developing MetS.
Article
Nutrition & Dietetics
Junteng Zhou, Ruicen Li, Ting Bao, Wei Jiang, Yan Huang
Summary: This study investigated the relationship between MPO and 25(OH)D in the general Chinese population, and found a negative association between circulating 25(OH)D and MPO.
FRONTIERS IN NUTRITION
(2022)
Article
Medicine, General & Internal
Duong Thuy Tran, Adriane M. Lewin, Louisa Jorm, Ian A. Harris
Summary: This study investigated elective rates of spinal fusion, decompression, and disc replacement procedures for people with degenerative conditions, by funding type. The privately funded procedures had higher rates and increased more rapidly than publicly funded procedures. These differences may indicate unnecessary procedures or a disparity in clinical need.
MEDICAL JOURNAL OF AUSTRALIA
(2023)
Article
Nutrition & Dietetics
Lu Han, Qi Wang
Summary: This study detected a potential association between dietary live microbe intake and cardiovascular diseases (CVD), showing that a high dietary live microbe intake was associated with a low prevalence of CVD, specifically in stroke and heart attack cases.
Article
Health Care Sciences & Services
Bernard X. W. Liew, Jan Hartvigsen, Marco Scutari, Alice Kongsted
Summary: This study identified two clinical subgroups of patients with long-lasting nonspecific low back pain. It found that psychological factors were strongly associated with disability in both subgroups, while physical factors and pain were also significant contributors in different ways. This highlights the importance of considering psychological factors in the treatment of low back pain.
JOURNAL OF CLINICAL EPIDEMIOLOGY
(2023)
Article
Medicine, General & Internal
Urszula Zywien, Katarzyna Barczyk-Pawelec, Tomasz Sipko
Summary: The study found that the pressure pain threshold and thoracolumbar angle were associated with low-intensity back pain in female subjects. In male subjects, low-intensity back pain was associated with torso angle, lumbosacral spine angle, and BMI.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Rei-Yeuh Chang, Sheri Hsueh-Hua Ho, Han-Lin Tsai, Malcolm Koo
Summary: The causes of noncardiac chest pain may be related to anxiety, depression, and chronic liver disease. This study found a significant association between anxiety, depression, and alcoholic liver disease in patients with noncardiac chest pain. Fatty liver disease and chronic hepatitis C were also associated with anxiety and depression, respectively. Clinicians should be aware of these correlations in their practice.
Article
Psychology, Multidisciplinary
Sameer Al-Ghamdi, Mamdouh M. Shubair, Khadijah Angawi, Jamaan Al-Zahrani, Abdulrahman Ali M. Khormi, Reem Falah Alshammari, Nawaf Safaq Alshammari, Raed Aldahash, Bander Yahya Otayf, Hayat Saleh Al-Zahrani, Manayir Sultan Aleshaiwi, Khaled K. Aldossari
Summary: The study found a significant positive association between neck/back pain and psychological distress/morbidity, with individuals experiencing neck/back pain having almost a 2.5 times greater risk of psychological problems. Females were also more likely to experience psychological distress/morbidity compared to males.
FRONTIERS IN PSYCHOLOGY
(2022)
Article
Respiratory System
Yoon Jae Won, Sook-Hyun Lee, Yu-Cheol Lim, Yoon Jae Lee, Maurits Van den Noort, Beom-Joon Lee, In-Hyuk Ha
Summary: The purpose of this study is to investigate the prevalence of common respiratory diseases and their association with sociodemographic characteristics, comorbidities, and medical history using 11 years of data from the Korea National Health and Nutrition Examination Survey (KNHANES), in order to provide foundational data for policy decision making and disease prevention measures.
CLINICAL RESPIRATORY JOURNAL
(2023)
Article
Nutrition & Dietetics
Hyunseong Kim, Jinyoung Hong, Junseon Lee, Wanjin Jeon, Changhwan Yeo, Yoonjae Lee, Seungho Baek, Inhyuk Ha
Summary: CAS pretreatment can protect hepatocytes from APAP-induced injury by inhibiting inflammation and oxidative stress through Sirt1/HO-1 signaling, suggesting its potential as a natural hepatoprotective drug.
Article
Nutrition & Dietetics
Doori Park, Jee-Eun Yoon, Boram Choi, Yoon-Jae Lee, In-Hyuk Ha
Summary: Menopause is a hormone-deficiency state that causes various symptoms such as facial flushing, vaginal dryness, and depression. Hormone-replacement therapy is commonly used, but it has side effects. In this study, a complex extract of Polygonatum sibiricum and Nelumbinis semen was found to improve menopause symptoms without side effects by increasing the expression of ER beta and restoring vaginal epithelial cell thickness. It also improved blood-lipid metabolism and alleviated osteoporosis. Therefore, it could be a natural treatment option for menopause.
Review
Medicine, General & Internal
Sookyung Lee, Jiyoon Yeo, Sook-Hyun Lee, Yoon Jae Lee, Sangkwan Lee, In-Hyuk Ha
Summary: This study analyzed the distribution and healthcare utilization of patients with migraine in South Korea using data from 2010-2018. The study identified the treatments frequently used in Western and Korean medicine hospitals, as well as their frequency of use and costs. The findings can be used as a basis for relevant health policy decisions.
Article
Biochemistry & Molecular Biology
Jin Young Hong, Hyunseong Kim, Junseon Lee, Wan-Jin Jeon, Changhwan Yeo, Hyun Kim, Yoon Jae Lee, In-Hyuk Ha
Summary: Epidural injection is a common nonsurgical treatment for lumbar spinal stenosis, and nerve block through epidural injection is a safe and effective method for low back or lower extremity pain. However, the long-term effectiveness of epidural injections in disc diseases has not been scientifically proven.
Article
Health Care Sciences & Services
Bo-Kyung Hwang, Kyoung Sun Park, Seung-Hyeok Ku, Sung-Hyun Kim, Hyun-Woo Moon, Mi-So Park, Hye-Kyung Baek, Jin Namgoong, Seung-Yoon Hwangbo, Ji-Yeon Seo, Yoon Jae Lee, Jinho Lee, In-Hyuk Ha
Summary: This study conducted a randomized controlled clinical trial to compare the effectiveness of integrated Korean medicine (IKM) with herbal medicine treatment to IKM monotherapy for post-accident syndrome persistent after the acute phase. The results showed that the combination of IKM and herbal medicine significantly improved the overall post-accident syndrome persistent after the acute phase and relieved somatic pain, maintaining this effect for at least 17 weeks.
Article
Health Care Sciences & Services
Nayoung Shin, Hyejin Nam, Dong Woo Kim, Yoon Jae Lee, Doori Kim, In-Hyuk Ha
Summary: This study investigated the effectiveness of integrative Korean medicine treatment in patients with pre-existing scoliosis who received inpatient care for traffic-accident-induced acute low back pain (LBP). A retrospective chart review and questionnaire-based follow-up survey were conducted on 674 patients diagnosed with scoliosis between January 2015 and June 2021. The results showed that integrative Korean medicine treatment significantly improved pain, lumbar dysfunction, and quality of life in these patients.
Article
Integrative & Complementary Medicine
Hui Yan Zhao, Chang-Hyun Han, Changsop Yang, Yoon Jae Lee, In-Hyuk Ha, Kyoung Sun Park
Summary: This study aims to evaluate the effectiveness and safety of pharmacopuncture therapy compared to physiotherapy for treating adhesive capsulitis. The study will be conducted as a randomized controlled trial with 50 participants receiving either pharmacopuncture therapy or physiotherapy over a 6-week period. The primary outcome measure is the numeric rating scale for shoulder pain, and secondary outcomes include various other measures of pain and disability. Analysis will be based on the intention-to-treat principle.
JOURNAL OF ACUPUNCTURE AND MERIDIAN STUDIES
(2023)
Article
Integrative & Complementary Medicine
Hyun Ji Cha, Chang-Hyun Han, Ju Hyun Jeon, Jeong Kyo Jeong, Hong Kyoung Kim, Changsop Yang, Byoung-Kab Kang, Min Ji Kim, Young Eun Choi, In-Hyuk Ha, Young Il Kim
Summary: This study aims to evaluate the effectiveness and safety of pharmacopuncture treatment for rotator cuff disease. A pragmatic, randomized, controlled, assessor-blinded trial will be conducted with 40 patients. The results will assess the effectiveness of the treatment in relieving pain and improving function, and provide data on non-surgical treatment for the disease.
JOURNAL OF ACUPUNCTURE AND MERIDIAN STUDIES
(2023)
Article
Multidisciplinary Sciences
Sowon Kim, Ye-Seul Lee, Jiyoon Yeo, Donghyo Lee, Dong Kun Ko, In-Hyuk Ha
Summary: This study analyzed the distribution and healthcare usage patterns of patients with atopic dermatitis using the 2010-2018 Health Insurance Review and Assessment Service data. The prevalence of atopic dermatitis showed a decreasing trend over time among patients aged <5, 5-14, and 15-24 years. The most commonly used Western medicine treatments were injections and oral medications involving topical corticosteroids, antihistamine agents, and oral steroids, while acupuncture therapy was the most used Korean medicine treatment.
Article
Clinical Neurology
Doori Kim, Eun-San Kim, Yoon Jae Lee, Jee Young Lee, Kyong Sun Park, So Young Jung, Changsop Yang, Chang-Hyun Han, In-Hyuk Ha
Summary: This study compared the efficacy, safety, and cost-effectiveness of non-pharmacological and pharmacological treatments for Lumbar disc herniation (LDH). The results showed that the non-pharmacological treatment group had significantly greater improvement and higher QALY value, with lower cost. This suggests that non-pharmacological treatment may be a more cost-effective approach.
JOURNAL OF PAIN RESEARCH
(2023)
Article
Health Care Sciences & Services
Sohyun Cho, Yu-Cheol Lim, Eun-Jung Kim, Yeoncheol Park, In-Hyuk Ha, Ye-Seul Lee, Yoon Jae Lee
Summary: This study aimed to analyze the trends and associated medical costs of conservative treatment for lumbar intervertebral disc disorders with radiculopathy in Korea. The number of patients receiving conservative treatment increased by more than 30% over a 10-year period, and medical costs also increased. Non-surgical treatments mainly included medication and physiotherapy, with non-opioid analgesics being the most commonly prescribed medication.
Article
Medicine, Research & Experimental
Jin Young Hong, Junseon Lee, Hyun Kim, Changhwan Yeo, Wan-Jin Jeon, Yoon Jae Lee, In- Hyuk Ha
Summary: Spinal cord injury often leads to the formation of glial scar tissue, hindering neural regeneration. This study demonstrates that Shinbaro2 (Sh2) can ameliorate glial scars and promote axon growth after spinal cord injury. Sh2 reduces inflammation, inhibits scar formation, and enhances motor function recovery.
BIOMEDICINE & PHARMACOTHERAPY
(2023)
Review
Medicine, General & Internal
Hyungwook Ji, Seungwon Shin, Yongjoo Kim, In-Hyuk Ha, Doori Kim, Yoon Jae Lee
Summary: This study analyzed the trend of surgical service utilization in patients with lumbar spinal stenosis (LSS) in Korea from 2010 to 2019. The findings showed an increase in the number of claims and medical expenses for surgeries, with decompression accounting for a higher proportion of first surgeries and fusion being more common in second surgeries. Patients who underwent fusion procedures had longer hospital stays and higher medical expenses across all sex and age groups.
MEDICINA-LITHUANIA
(2023)
Article
Medicine, General & Internal
Yen Min Wang, Yu-Cheol Lim, Deok-Sang Hwang, Yoon Jae Lee, In-Hyuk Ha, Ye-Seul Lee
Summary: This study investigated the trends in osteoporosis-related treatments and overall anticancer drug treatments in Korean patients with breast cancer from 2010 to 2019. The results showed that osteoporosis-related treatment and patient age were associated with the prescriptions of anticancer drugs.
MEDICINA-LITHUANIA
(2023)