A Wide Range of 3243A>G/tRNALeu(UUR) (MELAS) Mutation Loads May Segregate in Offspring through the Female Germline Bottleneck

Title
A Wide Range of 3243A>G/tRNALeu(UUR) (MELAS) Mutation Loads May Segregate in Offspring through the Female Germline Bottleneck
Authors
Keywords
Mitochondrial DNA, Mitochondrial myopathy, Oocytes, Skeletal muscles, Epithelium, Heteroplasmy, Biopsy, Somatic mutation
Journal
PLoS One
Volume 9, Issue 5, Pages e96663
Publisher
Public Library of Science (PLoS)
Online
2014-05-08
DOI
10.1371/journal.pone.0096663

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