Review
Oncology
Jing-Yu (Benjamin) Tan, Jianxia Zhai, Tao Wang, Hong-Juan Zhou, Isabella Zhao, Xian-Liang Liu
Summary: There is a growing number of clinical practice guidelines (CPGs) for non-pharmacological interventions for breast cancer survivors, but the development methodologies and recommendations are inconsistent. This study critically appraised and summarized the available non-pharmacological interventions recommended by CPGs for breast cancer survivors to manage symptoms and promote health. The findings showed variations in recommendations and limited evidence quality, indicating a need for more rigorous methods in developing high-quality CPGs.
FRONTIERS IN ONCOLOGY
(2022)
Review
Immunology
Madelon C. Vonk, Vanessa Smith, Petros P. Sfikakis, Maurizio Cutolo, Francesco del Galdo, James R. Seibold
Summary: Systemic sclerosis-associated interstitial lung disease (SSc-ILD) has been investigated with various drug treatments, with high-quality evidence supporting the use of cyclophosphamide, nintedanib, mycophenolate, and tocilizumab. Further research is needed to provide evidence for optimal treatment strategies.
AUTOIMMUNITY REVIEWS
(2021)
Review
Chemistry, Medicinal
Mengshi Tang, Yan Zeng, Weijun Peng, Xi Xie, Yongyu Yang, Biting Ji, Fen Li
Summary: This article reviews the effects of quercetin (QUE) on both articular and extra-articular manifestations of rheumatoid arthritis (RA), suggesting that QUE can inhibit inflammation and bone damage in the joints, as well as provide neuroprotection and cytoprotection.
DRUG DESIGN DEVELOPMENT AND THERAPY
(2022)
Review
Clinical Neurology
Bin Guan, Yuxuan Fan, Ruiyuan Zheng, Runhan Fu, Liang Yao, Wei Wang, Guoyu Li, Lingxiao Chen, Hengxing Zhou, Shiqing Feng
Summary: The study systematically reviewed and appraised guidelines for pharmacological treatments of spinal cord injury. Inconsistencies were found in the recommendations for methylprednisolone and GM-1. Evidence-based recommendations tended to recommend against, while consensus-based recommendations tended to recommend for.
Article
Medicine, General & Internal
Sofia Tejada, Sergio Ramirez-Estrada, Alexandre M. Tejo, Carlos G. Forero, Xavier Pomares, Miguel Gallego, Joan B. Soriano, James D. Chalmers, Jordi Rello
Summary: This study evaluated the quality of evidence supporting recommendations in international guidelines on bronchiectasis in adults, and found that newer guidelines had higher quality ratings. However, more high-quality evidence is still needed. The assessment identified four guidelines that were recommended for use, with the highest scores in the domains of scope and purpose.
EUROPEAN JOURNAL OF INTERNAL MEDICINE
(2022)
Review
Clinical Neurology
Neil N. Luu, Kevin T. Chorath, Brandon R. May, Nuvid Bhuiyan, Alvaro G. Moreira, Karthik Rajasekaran
Summary: Bell's palsy, a peripheral facial palsy of unknown cause, requires prompt treatment for patients to achieve complete recovery. Existing clinical practice guidelines show varying levels of quality, with future guidelines needing to focus on improving rigor of development, stakeholder involvement, and applicability.
JOURNAL OF NEUROLOGY
(2021)
Review
Dermatology
Mohamed Ali Babiker Mohamed, Ahmed M. El-Malky, Wael Ahmed Abdelwahab Abdelkarim, Mohamed Abdulmonem Salih Aabdeen, Tarig Hassan Elobid Ahmed, Hassan H. H. Sarsour, Munirah Mohammed Mosa, Yasser S. Amer, Abdulrahman Ali M. Khormi, Abdulmajeed Alajlan
Summary: A recent systematic review assessed and compared the most recently approved international CPGs using the AGREE II instrument. NICE guidelines showed the highest quality among the four selected CPGs, suggesting they are suitable for practice.
JOURNAL OF DERMATOLOGICAL TREATMENT
(2022)
Article
Cardiac & Cardiovascular Systems
Andrew Sephien, Denisse Camille Dayto, Tea Reljic, Wojciech Blonski, Nishant Nerella, Xavier Prida, Ambuj Kumar
Summary: This study assessed the methodological quality of current clinical practice guidelines (CPGs) for heart failure management and found that improvement is needed. The study suggests the use of a standardized approach to develop guidelines and the use of the AGREE II tool to enhance methodological rigor, reporting, and applicability of CPGs.
AMERICAN JOURNAL OF CARDIOLOGY
(2023)
Review
Plant Sciences
Juan -Min Li, Yun-Da Yao, Jin-Fang Luo, Jian-Xin Liu, Zhong-Qiu Liu, Yan Dong, Ying Xie, Hua Zhou
Summary: Sinomenine (SIN) has multiple pharmacological effects in rheumatoid arthritis (RA), including reducing the release of inflammatory cytokines and blocking the destruction of bone and cartilage. Its regulatory effects on alpha 7nAChR, methylation levels at specific GCG sites, and direct targeting of GBP5 gene enrich the possibilities for its treatment in inflammatory immune-related diseases.
Review
Rheumatology
Monica Schwartzman, Joerg Ermann, Kristine A. Kuhn, Sergio Schwartzman, Michael H. Weisman
Summary: This systematic literature review critically appraises study designs evaluating spondyloarthritis (SpA) phenotypes in patients with inflammatory bowel disease (IBD). The review finds that the characterization of SpA phenotypes in IBD patients remains incomplete and suggests the need for standardization of variables and definitions in order to advance clinical and research purposes.
Review
Rheumatology
Valeria Valerio, Michelle Kwok, Hal Loewen, Janice Winkler, Girish M. Mody, Rosie Scuccimarri, Michele Meltzer, Yewondwossen Mengistu, Candace H. Feldman, Michael E. Weinblatt, Diane Lacaille, Carol A. Hitchon, Ines Colmegna
Summary: Existing recommendations on the use of methotrexate (MTX) in rheumatoid arthritis (RA) show consistency in some aspects, such as baseline assessments, monitoring, and folic acid supplementation. However, there are disagreements in key aspects of MTX use, such as starting dose, route, titration, and monitoring intervals, highlighting the need for adaptations to facilitate implementation in least developed countries (LDCs).
CLINICAL RHEUMATOLOGY
(2021)
Article
Pediatrics
Kamal Kumar Singhal, Joseph L. Mathew, Jeanne M. Dsouza, Surbhi Agrawal, Ipsa Kutlehrria, Meenu Singh
Summary: This study aimed to assess the methodological quality of pediatric guidelines for COVID-19 management in India. The study found that the available guidelines have low methodological quality, particularly in terms of methodological rigor. There was diversity in the quality of different aspects of the guidelines. There were no significant differences in the quality of Indian vs. foreign guidelines, updated vs. original versions, and guidelines developed earlier vs. later in the pandemic.
INDIAN JOURNAL OF PEDIATRICS
(2022)
Review
Immunology
Rirong Chen, Jieqi Zheng, Chao Li, Qia Chen, Zhirong Zeng, Li Li, Minhu Chen, Shenghong Zhang
Summary: This systematic review evaluates existing models for predicting postoperative recurrence of Crohn's disease and finds that prognostic models have great potential for assessing the risk of recurrence. However, further validation is needed for the reliability and applicability of existing models.
FRONTIERS IN IMMUNOLOGY
(2023)
Review
Pharmacology & Pharmacy
Monika Mittal, Poonam Mehta, Swati Rajput, Singh Rajender, Naibedya Chattopadhyay
Summary: Resveratrol has shown significant efficacy in mitigating experimental rheumatoid arthritis in animal models, reducing paw swelling, arthritis symptoms, and improving histopathological damage and cartilage loss. It also decreases oxidative stress markers and pro-inflammatory cytokines while increasing anti-inflammatory cytokines.
EUROPEAN JOURNAL OF PHARMACOLOGY
(2021)
Review
Medicine, General & Internal
D. Abdelhafiz, T. Baker, D. A. Glascow, Ah Abdelhafiz
Summary: This study systematically explored the role of multiple biomarkers in the diagnosis, treatment, and prognosis of rheumatoid arthritis (RA). The results showed that these biomarkers are helpful tools in clinical practice for RA diagnosis, treatment monitoring, and prognosis prediction. However, further research is needed to investigate novel biomarkers that may be related to patient responsiveness.
POSTGRADUATE MEDICINE
(2023)
Article
Rehabilitation
Lucie Brosseau, Paulette Guitard, Chantal Laroche, Judy King, Julie Alexandra Barette, Dominique Cardinal, Sabrina Cavallo, Lucie Laferriere, Christina Lortie-Latreille, Jeremie Thibault, Ann Sutton, Roseline Galipeau, Jocelyne Tourigny, Karine Toupin-April, Laurianne Loew, Catrine Demers, Katrine Sauve-Schenk, Nicole Paquet, Jacinthe Savard, Josee Lagace, Denyse Pharand, Veronique Vaillancourt
PHYSIOTHERAPY CANADA
(2019)
Article
Rehabilitation
Judy King, Lucie Brosseau, Paulette Guitard, Chantal Laroche, Julie Alexandra Barette, Dominique Cardinal, Sabrina Cavallo, Lucie Laferriere, Karine Toupin-April, Marie-Eve Berube, Jennifer O'Neil, Jessane Castro, Cendy Kidjo, Sandy Fakhry, Ann Sutton, Roseline Galipeau, Jocelyne Tourigny, Josee Lagace, Catrine Demers, Nicole Paquet, Denyse Pharand, Laurianne Loew, Veronique Vaillancourt, Katrine Sauve-Schenk
PHYSIOTHERAPY CANADA
(2019)
Article
Multidisciplinary Sciences
Shirin M. Shallwan, Judy King, Roanne Thomas, Odette Thevenot, Gino De Angelis, Ala' S. Aburub, Lucie Brosseau
Review
Rehabilitation
Heather Flowers, Paulette Guitard, Judy King, Elizabeth Fitzpatrick, Daniel Berube, Julie Alexandra Barette, Dominique Cardinal, Sabrina Cavallo, Jennifer O'Neil, Marylene Charette, Laurence Cote, Nalia Cecilia Gurgel-Juarez, Karine Toupin-April, Shirin M. Shallwani, Michelle Dorion, Prinon Rahman, Maude Potvin-Gilbert, Vanessa Bartolini, Krystina B. Lewis, Rose Martini, Josee Lagace, Roseline Galipeau, Marie-Christine Ranger, Fauve Duquette-Laplante, Marie-France Perrier, Jacinthe Savard, Nicole Paquet, Jocelyne Tourigny, Marie-Eve Berube, Hussein Ba Haroon, Patrick Duong, Jacynthe Bigras, Julie Capistran, Laurianne Loew
Summary: This study successfully produced a French-Canadian translation of AMSTAR-2, confirmed its content validity, and examined inter-rater reliability. Through expert evaluation, back-translation, and experimental validation, an official version was established. Results indicated low ambiguity and good overall inter-rater reliability for the French-Canadian version of AMSTAR-2.
PHYSIOTHERAPY CANADA
(2022)
Article
Nursing
Brenda O'Neill, Mark Linden, Pam Ramsay, Alia Darweish Medniuk, Joanne Outtrim, Judy King, Bronagh Blackwood
Summary: The study aimed to develop a comprehensive and effective questionnaire to identify the key needs of ICU survivors during the recovery process, and evaluated its reliability and validity using advanced data analysis methods. Results showed that the questionnaire had high internal consistency and test-retest reliability, making it an effective tool for identifying the support needs of survivors.
NURSING IN CRITICAL CARE
(2022)
Article
Social Sciences, Interdisciplinary
Hussein Baharoon, Judy King
Summary: This study examined the challenges faced by Arab immigrants in adopting healthy lifestyle behaviors and managing stress related to acculturation and religiosity. Through face-to-face focus group discussions with Arab health promoters in Canada, it was found that certain religious or cultural beliefs may hinder physical activity, particularly for women and older individuals. However, religiosity can also play an important indirect role in stress management through socialization, family support, and coping strategies. Younger people in Arab communities appear to be more flexible in dealing with religious and cultural issues.
QUALITATIVE REPORT
(2022)
Article
Environmental Sciences
Barbara Greenwood Dufour, Laura Weeks, Gino De Angelis, Dave K. Marchand, David Kaunelis, Melissa Severn, Melissa Walter, Nicole Mittmann
Summary: This article describes how health technology assessment (HTA) is evolving to address climate change and provide decision-makers with information to reduce the environmental impact of healthcare systems. It explores the challenges of incorporating the environment domain and determining when environmental impact assessments are necessary.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Rehabilitation
Shirin M. Shallwani, Roanne Thomas, Stephane Poitras, Karine Toupin-April, Grainne Sheill, Judy King
Summary: Canadian oncology physiotherapists demonstrate knowledge of the safety and importance of physical activity for individuals with advanced cancer, as well as considerations related to cancer. They emphasize a patient-centered approach to support this population, focusing on promoting safe and meaningful physical activity, optimizing function, and alleviating symptom burden.
PHYSIOTHERAPY THEORY AND PRACTICE
(2022)
Article
Rehabilitation
Jennifer O'Neil, Jacquie van Ierssel, Judy King, Heidi Sveistrup
Summary: The COVID-19 pandemic has led to a rapid change in the way physiotherapy services are delivered, with a significant increase in the implementation of telerehabilitation. This study aimed to identify the barriers and facilitators of telerehabilitation clinical implementation by examining the experiences of Canadian physiotherapists during the initial wave of the pandemic. The results showed that while physiotherapists enjoyed and found telerehabilitation useful, limited access to implementation evidence, a reduced hands-on approach, and a lack of validated remote assessments were reported as barriers.
PHYSIOTHERAPY CANADA
(2023)
Article
Rehabilitation
Shirin M. Shallwani, Roanne Thomas, Judy King, Karine Toupin-April, Stephane Poitras
Summary: This study explored the perspectives and experiences of leisure-time physical activity (LTPA) in individuals with stage 4 cancer. The participants emphasized the importance of intentional LTPA, which was linked to physical well-being, social connections, and personal meanings. They desired personalized, integrated, and accessible support for LTPA in cancer care.
DISABILITY AND REHABILITATION
(2023)
Article
Clinical Neurology
Jacqueline van Ierssel, Jennifer O'Neil, Judy King, Roger Zemek, Heidi Sveistrup
Summary: According to the survey, clinicians generally agreed that telehealth can be used for concussion assessment and management, but have concerns about its limitations in performing certain examinations and therapies.
JOURNAL OF HEAD TRAUMA REHABILITATION
(2023)
Review
Health Policy & Services
Shirin M. Shallwani, Marie-Christine Ranger, Roanne Thomas, Lucie Brosseau, Stephane Poitras, Lindsey Sikora, Judy King
Summary: This review highlights a recent increase in research on leisure-time physical activity in advanced cancer, particularly in studies examining exercise interventions using traditional quantitative methods. There is still limited understanding of patient experiences and perceptions towards LPA, as well as little knowledge about other leisure activities for this population. Further research is needed to address the gaps in the current literature and develop personalized, evidence-based supportive care strategies in cancer care.
PALLIATIVE & SUPPORTIVE CARE
(2021)
Article
Social Sciences, Interdisciplinary
Roanne Thomas, Mary Egan, Wendy Gifford, Pamela Grassau, Judy King, Alysson Rheault, Josee Boulanger
Summary: Researchers will work with women living with cancer-related impairments to explore how creative practices can contribute to new understandings of well-being. The participants will create artwork, participate in interviews, and provide feedback on a film produced from workshop recordings, leading to a public film screening and exhibit of participants' work.
INTERNATIONAL JOURNAL OF QUALITATIVE METHODS
(2021)
Review
Rehabilitation
Shirin M. Shallwani, Lucie Brosseau, Roanne Thomas, Stephane Poitras, Lindsey Sikora, Marie-Christine Ranger, Judy King
PHYSICAL THERAPY REVIEWS
(2019)
Review
Critical Care Medicine
J. King, B. O'Neill, P. Ramsay, M. A. Linden, A. Darweish Medniuk, J. Outtrim, B. Blackwood
