Potential Role of IL-17-Producing iNKT Cells in Type 1 Diabetes

Double deficiency in IL-17 and IFN-γ signalling significantly suppresses the development of diabetes in the NOD mouse

(2013) G. Kuriya et al.   DIABETOLOGIA

   T Cells Are Essential Effectors of Type 1 Diabetes in the Nonobese Diabetic Mouse Model

(2013) J. G. M. Markle et al.   JOURNAL OF IMMUNOLOGY

Peripheral and Islet Interleukin-17 Pathway Activation Characterizes Human Autoimmune Diabetes and Promotes Cytokine-Mediated  -Cell Death

(2011) S. Arif et al.   DIABETES

NOD mice contain an elevated frequency of iNKT17 cells that exacerbate diabetes

(2011) Yannick Simoni et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Proinflammatory Environment Dictates the IL-17-Producing Capacity of Human Invariant NKT Cells

(2011) L. Moreira-Teixeira et al.   JOURNAL OF IMMUNOLOGY

Interleukin-1  Produced in Response to Islet Autoantigen Presentation Differentiates T-Helper 17 Cells at the Expense of Regulatory T-Cells: Implications for the Timing of Tolerizing Immunotherapy

(2010) S. Bertin-Maghit et al.   DIABETES

Cutting Edge: Increased IL-17-Secreting T Cells in Children with New-Onset Type 1 Diabetes

(2010) A. K. Marwaha et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Crucial Role of IL-1 and IL-23 in the Innate IL-17 Response of Peripheral Lymph Node NK1.1- Invariant NKT Cells to Bacteria

(2010) J.-M. Doisne et al.   JOURNAL OF IMMUNOLOGY

IL-17 Immunity in Human Type 1 Diabetes

(2010) J. Honkanen et al.   JOURNAL OF IMMUNOLOGY

Inhibition of Th17 Cells Regulates Autoimmune Diabetes in NOD Mice

(2009) J. A. Emamaullee et al.   DIABETES

Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells

(2009) Natalia Martin-Orozco et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interleukin-17-producing γδ+T cells protect NOD mice from type 1 diabetes through a mechanism involving transforming growth factor-β

(2009) Gencheng Han et al.   IMMUNOLOGY

Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice

(2009) David Bending et al.   JOURNAL OF CLINICAL INVESTIGATION

Skin and Peripheral Lymph Node Invariant NKT Cells Are Mainly Retinoic Acid Receptor-Related Orphan Receptor  t+ and Respond Preferentially under Inflammatory Conditions

(2009) J.-M. Doisne et al.   JOURNAL OF IMMUNOLOGY

Monocytes from Patients with Type 1 Diabetes Spontaneously Secrete Proinflammatory Cytokines Inducing Th17 Cells

(2009) E. M. Bradshaw et al.   JOURNAL OF IMMUNOLOGY

Innocuous IFNγ induced by adjuvant-free antigen restores normoglycemia in NOD mice through inhibition of IL-17 production

(2008) Renu Jain et al.   JOURNAL OF EXPERIMENTAL MEDICINE