Ex Vivo Expanded Human Regulatory T Cells Delay Islet Allograft Rejection via Inhibiting Islet-Derived Monocyte Chemoattractant Protein-1 Production in CD34+ Stem Cells-Reconstituted NOD-scid IL2rγnull Mice
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Title
Ex Vivo Expanded Human Regulatory T Cells Delay Islet Allograft Rejection via Inhibiting Islet-Derived Monocyte Chemoattractant Protein-1 Production in CD34+ Stem Cells-Reconstituted NOD-scid IL2rγnull Mice
Authors
Keywords
Regulatory T cells, Mouse models, T cells, Islet transplantation, Immune response, Transplant rejection, Blood sugar, Spleen
Journal
PLoS One
Volume 9, Issue 3, Pages e90387
Publisher
Public Library of Science (PLoS)
Online
2014-03-04
DOI
10.1371/journal.pone.0090387
References
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- Adoptive Transfer With In Vitro Expanded Human Regulatory T Cells Protects Against Porcine Islet Xenograft Rejection via Interleukin-10 in Humanized Mice
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- (2012) Mauro Di Ianni et al. TRANSFUSION AND APHERESIS SCIENCE
- Molecular Mechanisms of Treg-Mediated T Cell Suppression
- (2012) Angelika Schmidt et al. Frontiers in Immunology
- Immunological Applications of Stem Cells in Type 1 Diabetes
- (2011) Paolo Fiorina et al. ENDOCRINE REVIEWS
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- (2011) E. Tresoldi et al. HAEMATOLOGICA
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- (2010) K. E. Lamb et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Parameters for establishing humanized mouse models to study human immunity: Analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rγnull mutation
- (2010) Michael A. Brehm et al. CLINICAL IMMUNOLOGY
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- In vivo prevention of transplant arteriosclerosis by ex vivo–expanded human regulatory T cells
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- Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r null humanized mice
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- Ex Vivo–Expanded Human Regulatory T Cells Prevent the Rejection of Skin Allografts in a Humanized Mouse Model
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- Current Advances and Travails in Islet Transplantation
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- The analysis of the functions of human B and T cells in humanized NOD/shi-scid/γcnull (NOG) mice (hu-HSC NOG mice)
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- Superantigen-Activated Regulatory T Cells Inhibit the Migration of Innate Immune Cells and the Differentiation of Naive T Cells
- (2009) Y. Tanriver et al. JOURNAL OF IMMUNOLOGY
- Alloreactivity but Failure to Reject Human Islet Transplants by Humanized Balb/c/Rag2−/−gc−/−Mice
- (2009) S. Jacobson et al. SCANDINAVIAN JOURNAL OF IMMUNOLOGY
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- (2008) U. Hofer et al. JOURNAL OF VIROLOGY
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- (2007) Marie King et al. CLINICAL IMMUNOLOGY
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