Direct T Cell Activation via CD40 Ligand Generates High Avidity CD8+ T Cells Capable of Breaking Immunological Tolerance for the Control of Tumors

TCR Antagonism by Peptide Requires High TCR Expression

(2014) D. S. Jones et al.   JOURNAL OF IMMUNOLOGY

Priming of a Novel Subset of CD28+ Rapidly Expanding High-Avidity Effector Memory CTL by Post Maturation Electroporation-CD40L Dendritic Cells Is IL-12 Dependent

(2014) M. A. DeBenedette et al.   JOURNAL OF IMMUNOLOGY

Comparison of Vaccine-Induced Effector CD8 T Cell Responses Directed against Self- and Non-Self-Tumor Antigens: Implications for Cancer Immunotherapy

(2013) S. R. Pedersen et al.   JOURNAL OF IMMUNOLOGY

Xenogeneic Human p53 DNA Vaccination by Electroporation Breaks Immune Tolerance to Control Murine Tumors Expressing Mouse p53

(2013) Ruey-Shyang Soong et al.   PLoS One

Memory T Cell Subsets, Migration Patterns, and Tissue Residence

(2012) Scott N. Mueller et al.   Annual Review of Immunology

The Use of Agonistic Anti-CD40 Therapy in Treatments for Cancer

(2012) Andrea Khong et al.   INTERNATIONAL REVIEWS OF IMMUNOLOGY

CD40-targeted adenoviral cancer vaccines: the long and winding road to the clinic

(2012) Basav N. Hangalapura et al.   JOURNAL OF GENE MEDICINE

Influenza-induced, helper-independent CD8+ T cell responses use CD40 costimulation at the late phase of the primary response

(2012) Shirley G. K. Seah et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Pilot study of dacetuzumab in combination with rituximab and gemcitabine for relapsed or refractory diffuse large B-cell lymphoma

(2012) Andres Forero-Torres et al.   LEUKEMIA & LYMPHOMA

Tumor-Targeted Delivery of IL-2 by NKG2D Leads to Accumulation of Antigen-Specific CD8+ T Cells in the Tumor Loci and Enhanced Anti-Tumor Effects

(2012) Tae Heung Kang et al.   PLoS One

Adjuvant Combination and Antigen Targeting as a Strategy to Induce Polyfunctional and High-Avidity T-Cell Responses against Poorly Immunogenic Tumors

(2011) F. Aranda et al.   CANCER RESEARCH

Electroporation delivery of DNA vaccines: prospects for success

(2011) Niranjan Y Sardesai et al.   CURRENT OPINION IN IMMUNOLOGY

A human memory T cell subset with stem cell–like properties

(2011) Luca Gattinoni et al.   NATURE MEDICINE

CD40 Agonists Alter Tumor Stroma and Show Efficacy Against Pancreatic Carcinoma in Mice and Humans

(2011) G. L. Beatty et al.   SCIENCE

Head and neck cancer: Response to p53-based therapeutics

(2010) Jackie Nemunaitis et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Heterologous Prime/Boost Immunization With p53-based Vaccines Combined With Toll-like Receptor Stimulation Enhances Tumor Regression

(2010) Hidenobu Ishizaki et al.   JOURNAL OF IMMUNOTHERAPY

Selective Transduction of Dendritic Cells in Human Lymph Nodes and Superior Induction of High-avidity Melanoma-reactive Cytotoxic T Cells by a CD40-targeted Adenovirus

(2010) Basav N. Hangalapura et al.   JOURNAL OF IMMUNOTHERAPY

Translating p53 into the clinic

(2010) Chit Fang Cheok et al.   Nature Reviews Clinical Oncology

p53 family members in cancer diagnosis and treatment

(2010) Alice Machado-Silva et al.   SEMINARS IN CANCER BIOLOGY

Optimized Peptide Vaccines Eliciting Extensive CD8 T-Cell Responses with Therapeutic Antitumor Effects

(2009) H.-I. Cho et al.   CANCER RESEARCH

Selected Toll-like Receptor Ligands and Viruses Promote Helper-Independent Cytotoxic T Cell Priming by Upregulating CD40L on Dendritic Cells

(2009) Susan Johnson et al.   IMMUNITY

Self-antigen–specific CD8+T cell precursor frequency determines the quality of the antitumor immune response

(2009) Gabrielle A. Rizzuto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Use of tumour-responsive T cells as cancer treatment

(2009) Mary L Disis et al.   LANCET

Wnt signaling arrests effector T cell differentiation and generates CD8+ memory stem cells

(2009) Luca Gattinoni et al.   NATURE MEDICINE

Macrophage CD40 signaling: A pivotal regulator of disease protection and pathogenesis

(2009) Jill Suttles et al.   SEMINARS IN IMMUNOLOGY

Administration of HPV DNA vaccine via electroporation elicits the strongest CD8+ T cell immune responses compared to intramuscular injection and intradermal gene gun delivery

(2009) Simon R. Best et al.   VACCINE