Anti-Osteoclastogenic Activity of Praeruptorin A via Inhibition of p38/Akt-c-Fos-NFATc1 Signaling and PLCγ-Independent Ca2+ Oscillation

Bisphosphonate-associated adverse events

(2014) Peter Papapetrou   Hormones-International Journal of Endocrinology and Metabolism

Glutaredoxin2 isoform b (Glrx2b) promotes RANKL-induced osteoclastogenesis through activation of the p38-MAPK signaling pathway

(2012) Jeong-Tae Yeon et al.   BMB Reports

Akt Induces Osteoclast Differentiation through Regulating the GSK3 /NFATc1 Signaling Cascade

(2011) J. B. Moon et al.   JOURNAL OF IMMUNOLOGY

Stereoselective metabolism of (±)-praeruptorin A, a calcium channel blocker from Peucedani Radix, in pooled liver microsomes of rats and humans

(2011) Y. L. Song et al.   XENOBIOTICA

The Role of Osteoclast-Associated Receptor in Osteoimmunology

(2010) K. Nemeth et al.   JOURNAL OF IMMUNOLOGY

Praeruptorin a inhibits lipopolysaccharide-induced inflammatory response in murine macrophages through inhibition of NF-κB pathway activation

(2010) Peng-Jiu Yu et al.   PHYTOTHERAPY RESEARCH

Ca2+-NFATc1 signaling is an essential axis of osteoclast differentiation

(2009) Takako Negishi-Koga et al.   IMMUNOLOGICAL REVIEWS

Anti-resorptive saurolactam exhibits in vitro anti-inflammatory activity via ERK–NF-κB signaling pathway

(2009) Su-Ui Lee et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Saurolactam inhibits osteoclast differentiation and stimulates apoptosis of mature osteoclasts

(2009) Myung Hee Kim et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Osteoclast receptors and signaling

(2008) Andrea Del Fattore et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The Tec Family Tyrosine Kinase Btk Regulates RANKL-induced Osteoclast Maturation

(2008) Seoung Hoon Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

NFATc1 Induces Osteoclast Fusion Via Up-Regulation of Atp6v0d2 and the Dendritic Cell-Specific Transmembrane Protein (DC-STAMP)

(2007) Kabsun Kim et al.   MOLECULAR ENDOCRINOLOGY