Article
Chemistry, Multidisciplinary
Jairo Azocar-Gallardo, Alex Ojeda-Aravena, Eduardo Baez-San Martin, Victor Campos-Uribe, Luis Gonzalez-Rojas, Maria A. Castillo Cerda, Jose Manuel Garcia-Garcia
Summary: The aim of this study was to determine the influence of body composition on cardiorespiratory fitness and metabolic markers. The results showed that higher fat-free mass and lower body mass index were positively related to better cardiorespiratory fitness, regardless of insulin resistance status.
APPLIED SCIENCES-BASEL
(2023)
Article
Nutrition & Dietetics
SoJung Lee, Rubin Pooni, Silva Arslanian, Minsub Han, Jennifer L. Kuk
Summary: In adolescents with high cardiorespiratory fitness and muscular strength, there were lower levels of total and regional fat, as well as higher insulin sensitivity. The differences were more pronounced for cardiorespiratory fitness, showing a stronger association with these markers even after adjusting for muscular strength.
APPLIED PHYSIOLOGY NUTRITION AND METABOLISM
(2021)
Article
Endocrinology & Metabolism
Reem S. Shawar, Maurice Puyau, Roman Shypailo, Salma Musaad, Nancy F. Butte, Fida Bacha
Summary: This study investigates the relationship between adiposity, insulin resistance, cardiorespiratory fitness, and bone mass in Hispanic youth. The findings suggest that adiposity is negatively related to bone mass, and this relationship is partially mediated by insulin resistance, while cardiorespiratory fitness may attenuate it.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Endocrinology & Metabolism
Yanyan Dai, Yujuan Li, Shu Yang, Weiwei Xu, Hong Jia, Chao Yang
Summary: Weight change is associated with the risk of metabolic abnormalities. Long-term excessive weight gain is positively associated with an increased risk of metabolic abnormalities in non-overweight/obese individuals, while long-term weight loss is a protective factor for metabolic health in overweight/obese individuals.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Sport Sciences
Eero A. Haapala, Tuomo Tompuri, Niina Lintu, Anna Viitasalo, Kai Savonen, Timo A. Lakka, Jari A. Laukkanen
Summary: Cardiorespiratory fitness is inversely associated with cardiometabolic risk factors, but the association weakens when considering body size and composition. Regardless of the scaling approach, cardiorespiratory fitness is consistently positively associated with high-density lipoprotein cholesterol levels.
JOURNAL OF SCIENCE AND MEDICINE IN SPORT
(2022)
Article
Multidisciplinary Sciences
Nicholas Castro, Lauren C. Bates, Gabriel Zieff, Patricia Pagan Lassalle, James Faulkner, Sally Lark, Michael Hamlin, Paula Skidmore, T. Leigh Signal, Michelle A. Williams, Simon Higgins, Lee Stoner
Summary: This study aimed to investigate the associations between dietary patterns, activity behaviors, and physical fitness with adiposity in preadolescent children. The results showed that cardiorespiratory fitness was strongly associated with body fat percentage, fat mass, BMI, and waist to hip ratio. Fruit and vegetable consumption patterns had a negligible association with body fat percentage. Therefore, future interventions should focus on improving cardiorespiratory fitness to reduce childhood obesity.
Article
Sport Sciences
Eero A. Haapala, Tanja Sjoros, Saara Laine, Taru Garthwaite, Petri Kallio, Maria Saarenhovi, Henri Vaha-Ypya, Eliisa Loyttyniemi, Harri Sievanen, Noora Houttu, Kirsi Laitinen, Kari Kalliokoski, Juhani Knuuti, Tommi Vasankari, Ilkka H. Heinonen
Summary: The study suggests that using BM-1 as a scaling factor can confound the association between CRF and cardiometabolic risk in overweight/obese adults with metabolic syndrome.
JOURNAL OF SPORTS MEDICINE AND PHYSICAL FITNESS
(2022)
Article
Endocrinology & Metabolism
Min Tang, Xiao-Hui Wei, Han Cao, Qin Zhen, Fang Liu, Yu-Fan Wang, Neng-Guang Fan, Yong-De Peng
Summary: The study aimed to investigate the correlation between the Chinese visceral adiposity index (CVAI) and metabolic-associated fatty liver disease (MAFLD) in Chinese adults with type 2 diabetes mellitus (T2DM). The results showed that CVAI was positively correlated with MAFLD, suggesting that it could be used as a diagnostic indicator for MAFLD in clinical practice for T2DM patients.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Gastroenterology & Hepatology
Jiaye Liu, Ibrahim Ayada, Xiaofang Zhang, Ling Wang, Yang Li, Tianfu Wen, Zhongren Ma, Marco J. Bruno, Robert J. de Knegt, Wanlu Cao, Maikel P. Peppelenbosch, Mohsen Ghanbari, Zhihui Li, Qiuwei Pan
Summary: This study estimated the global prevalence of MAFLD in overweight and obese adults to be 50.7%. Male had a significantly higher MAFLD prevalence than female, and comorbidities such as type 2 diabetes and metabolic syndrome were found to have high prevalence rates.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
(2022)
Article
Endocrinology & Metabolism
Eero A. Haapala, Marja H. Leppanen, Maarit Lehti, Niina Lintu, Tuomo Tompuri, Anna Viitasalo, Ursula Schwab, Timo A. Lakka
Summary: Cardiorespiratory fitness is associated with a cardioprotective metabolite profile in children, independent of body fat percentage. Associations between fitness and certain serum metabolites remained significant even after adjusting for body fat.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Nutrition & Dietetics
Lorena Villalba-Heredia, Cristina Comeras-Chueca, Alejandro Gonzalez-Aguero, Daniel Domingo-del-Val, Pilar Calmarza, German Vicente-Rodriguez, Jose A. Casajus, Angel Matute-Llorente
Summary: The study found no significant relationship between serum 25-hydroxyvitamin D and cardiorespiratory fitness parameters in prepubertal obese and overweight children. However, the cardiorespiratory fitness of these children was found to be relatively poor compared to normal-weight children.
Article
Endocrinology & Metabolism
Zeyu Liu, Qin Huang, Bi Deng, Minping Wei, Xianjing Feng, Fang Yu, Jie Feng, Yang Du, Jian Xia
Summary: CVAI is found to be associated with stroke risk in patients with MetS, with each 1 SD increase in CVAI associated with a 1.52-fold higher risk of stroke.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Health Care Sciences & Services
Patricia Lizett Rodriguez-Carrillo, Priscila Irene Aguirre-Tostado, Maciste H. Macias-Cervantes, Jorge Alejandro Alegria-Torres, Claudia Luevano-Contreras
Summary: The study proposed Mexican adiposity indices (MAIs) and biochemical-anthropometric indices (BAIs), that performed well in identifying CR and MetS in Mexican adults. The VFA cut-off value of 100.3 cm(2) was found to be effective in identifying CR in Mexican men.
Article
Sport Sciences
Jooa Norha, Tanja Sjoros, Taru Garthwaite, Saara Laine, Maria Saarenhovi, Petri Kallio, Kirsi Laitinen, Noora Houttu, Henri Vaha-Ypya, Harri Sievanen, Eliisa Loyttyniemi, Tommi Vasankari, Juhani Knuuti, Kari K. Kalliokoski, Ilkka H. A. Heinonen
Summary: A study on adults with metabolic syndrome found that reducing sedentary behavior without adding exercise training did not significantly improve maximal oxygen uptake (VO2max). However, increasing daily step count may increase VO2max.
SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS
(2023)
Article
Engineering, Biomedical
Bhupinder Singh, Mami M. Takeda, Melanie F. Niino, Jennifer D. Goulart, Amber J. Hammons, Jennifer M. Roos, H. John Yack
Summary: This study found that fitness level is not related to changes in biomechanics pre- to post-fatigue in overweight and obese children, while adiposity and lower extremity strength are the main influencing factors on joint moments in the frontal and sagittal planes. Skinfold estimates were predictive of %body fat from air displacement plethysmography, and there was agreement between the two methods without bias.
CLINICAL BIOMECHANICS
(2021)
Article
Clinical Neurology
Han Kyu Na, Han-Kyeol Kim, Hye Sun Lee, Mina Park, Jae Hoon Lee, Young Hoon Ryu, Hanna Cho, Chul Hyoung Lyoo
Summary: By studying 272 participants with MRI and PET scans, we found that a high degree of temporal lobe perivascular space (EPVS) is associated with a higher likelihood of amyloid positivity in patients with Alzheimer's disease. This finding suggests that impaired perivascular drainage may be related to cerebral amyloidosis.
ANNALS OF NEUROLOGY
(2023)
Article
Oncology
Chang Ik Yoon, Hye Sun Lee, Soyoung Jeon, Dooreh Kim, Woo-Chan Park
Summary: This study aimed to clarify the relationship between adjuvant tamoxifen use and cataracts risk using a nationwide longitudinal population-based registry. The results showed that adjuvant tamoxifen was not a significant risk factor for increased cataracts diagnosis and surgery in patients with DCIS.
BREAST CANCER RESEARCH AND TREATMENT
(2023)
Article
Nutrition & Dietetics
Jun-Hyuk Lee, Yu-Jin Kwon, Hye Sun Lee, Jee Hye Han, Boyoung Joung, Sung Jin Kim
Summary: This study confirms an inverse dose-dependent association between serum 25-hydroxyvitamin D levels and elevated intraocular pressure (EIOP) in a large sample of 15,338 individuals. Each unit increase in serum 25-hydroxyvitamin D is associated with a 3% decrease in the odds of having EIOP. Compared to individuals deficient in 25-hydroxyvitamin D, those with insufficiency and sufficiency have a 28% and 49% lower odds of EIOP, respectively. Therefore, clinical assessment of intraocular pressure may be helpful in the treatment and prevention of glaucoma in patients with insufficient 25-hydroxyvitamin D.
Article
Nutrition & Dietetics
Yu-Jin Kwon, Hye Sun Lee, Goeun Park, Juyeon Yang, Hyung-Mi Kim, Ji-Won Lee
Summary: This study investigated the association between dietary zinc intake and total deaths, cancer, and cardiovascular disease death. The results showed that dietary zinc intake was inversely associated with all-cause mortality and cardiovascular disease mortality, but not with cancer mortality. These findings suggest that recommending optimal dietary zinc intake is beneficial for human health.
Article
Geriatrics & Gerontology
Yerim Kim, Jae-Hoon Lee, Eun-Suk Cho, Hye Sun Lee, Su-Jin Shin, Eun Jung Park, Seung Hyuk Baik, Kang Young Lee, Jeonghyun Kang
Summary: This study aimed to examine the individual and synergistic effects of different prognostic markers related to skeletal muscle quality and serum albumin levels in patients with colorectal cancer (CRC). The albumin-myosteatosis gauge (AMG) was found to be a meaningful predictor of survival, with superior prognostic value compared to skeletal muscle index (SMI), skeletal muscle radiodensity (SMD), and albumin alone. Further studies are needed to determine their significance in different ethnic groups.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2023)
Article
Oncology
Jiin Ryu, Eun-Young Lee, Jihee Min, Sujin Yeon, Ji-Won Lee, Sang Hui Chu, Hyangkyu Lee, Seung Il Kim, Jee Ye Kim, Seho Park, Justin Y. Jeon
Summary: This 12-month randomized controlled trial investigates the effects of tailored home-based exercise programs on short-term and long-term physiological outcomes in patients with breast cancer. The study found that exercise interventions customized to patients' treatment phase, surgery type, and physical function can improve shoulder function, body composition, and insulin resistance. These findings provide guidance for the development of effective exercise programs for patients with breast cancer post-operatively.
Article
Dentistry, Oral Surgery & Medicine
Hyun-Jeong Lee, Ji-Won Lee, Sue Kim, Yu-Jin Kwon
Summary: This study found that TyG, TyG-BMI, TyG-WC, and TyG-WHtR are significantly associated with the risk of periodontitis, and TyG-WHtR has the highest predictive performance.
JOURNAL OF PERIODONTAL RESEARCH
(2023)
Article
Medicine, General & Internal
Lan-Ju Lee, Seong-Youl Choi, Hye-Sun Lee, Sang-Woo Han
Summary: This study aimed to analyze the difference in independency enhancement between VR-based training for daily activities and cognitive and motor functional training in stroke patients. The results showed that after VR-based intervention, daily activities, cognitive function, and upper extremities function were improved. It was concluded that training for daily activities based on tasks with objectives was more effective when introduced early.
Article
Clinical Neurology
Sung Hyun Noh, Hye Sun Lee, Go Eun Park, Yoon Ha, Jeong Yoon Park, Sung Uk Kuh, Dong Kyu Chin, Keun Su Kim, Yong Eun Cho, Sang Hyun Kim, Kyung Hyun Kim
Summary: This study aimed to create an ideal machine learning model to predict mechanical complications in adult spinal deformity (ASD) surgery based on GAPB factors. The data of 238 consecutive patients with ASD were analyzed using machine learning algorithms, and significant differences in certain scores were found between the complication and no complication groups. The prediction accuracy reached 1.000 and 0.732 on the training and test sets, respectively. Therefore, the machine learning model can effectively predict mechanical complications after ASD surgery.
Article
Biochemistry & Molecular Biology
Sanghoon Kim, Ji-Won Lee, Yaeji Lee, Youhyun Song, John A. Linton
Summary: This study found a correlation between the triglyceride-glucose (TyG) index and mean low-density lipoprotein (LDL) particle size. The results showed that the TyG index cutoff value for sdLDL particle predominance was close to the cutoff value of diabetes risk in Koreans.
LIPIDS IN HEALTH AND DISEASE
(2023)
Article
Nutrition & Dietetics
Jun Young Lim, Young Min Kim, Hye Sun Lee, Jeonghyun Kang
Summary: A machine learning algorithm was developed to predict skeletal muscle gauge in colorectal cancer patients using clinical and inflammatory markers. The algorithm demonstrated superior performance compared to single variables in predicting low skeletal muscle gauge. This model can serve as a screening tool for assessing and intervening in muscle health during treatment.
Article
Endocrinology & Metabolism
Jun-Hyuk Lee, Soyoung Jeon, Hye Sun Lee, Yu-Jin Kwon
Summary: This study investigated the association between waist circumference (WC) changes and the incidence of non-alcoholic fatty liver disease (NAFLD). The results showed that an increasing WC trend was associated with a higher risk of NAFLD, independent of abdominal obesity status. Monitoring WC changes may help identify individuals at risk for NAFLD and promote lifestyle modifications for prevention.
OBESITY RESEARCH & CLINICAL PRACTICE
(2023)
Article
Health Care Sciences & Services
Hyun-Joung No, Young Chul Yoo, Young Jun Oh, Hye Sun Lee, Soyoung Jeon, Ki Hong Kweon, Na Young Kim
Summary: This study retrospectively analyzed the effects of sugammadex compared with neostigmine on postoperative recovery in patients with myasthenia gravis who underwent video-assisted thoracoscopic surgery. The study found that patients who received sugammadex had a significantly shorter postoperative hospital stay compared to those who received neostigmine.
JOURNAL OF PERSONALIZED MEDICINE
(2023)
Article
Medicine, General & Internal
Hyunkyung Shin, Hye Sun Lee, Boung Chul Lee, Goeun Park, Khishigbayar Uranbileg, Yoon Park, Minhyeong Yun, Jeong-Ho Seok
Summary: The purpose of this study was to determine the prevalence and clinical characteristics of borderline personality disorder (BPD) in South Korea using the Korean National Health Insurance database. The results showed a relatively low prevalence of BPD compared to other countries, but a steady increase in the number of BPD patients over the past decade, possibly due to increased awareness of mental health.
YONSEI MEDICAL JOURNAL
(2023)
Article
Pediatrics
Ehn-Young Kim, Hye-Won Lee, Ji-Won Lee, Yu-Jin Kwon, Nak-Hoon Son
Summary: The study aimed to analyze the trends in serum uric acid (SUA) levels among Korean children and adolescents over a 5-year period, considering factors such as age, sex, obesity, and abdominal obesity. The study utilized nationally representative data from the Korea National Health and Nutritional Examination Survey conducted from 2016 to 2020. The findings showed a significant increase in SUA levels among boys with obesity or abdominal obesity, indicating the need for further research on the health outcomes associated with SUA in this population.
EUROPEAN JOURNAL OF PEDIATRICS
(2023)