Discovery of a Novel Target for the Dysglycemic Chromogranin A Fragment Pancreastatin: Interaction with the Chaperone GRP78 to Influence Metabolism

Failure of the Adaptive Unfolded Protein Response in Islets of Obese Mice Is Linked With Abnormalities in  -Cell Gene Expression and Progression to Diabetes

(2012) J. Y. Chan et al.   DIABETES

Decreased expression of endoplasmic reticulum chaperone GRP78 in liver of diabetic mice

(2011) Nobuyuki Yamagishi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Differential regulation of adaptive and apoptotic unfolded protein response signalling by cytokine-induced nitric oxide production in mouse pancreatic beta cells

(2011) J. Y. Chan et al.   DIABETOLOGIA

Endoplasmic reticulum stress, obesity and diabetes

(2011) Miriam Cnop et al.   TRENDS IN MOLECULAR MEDICINE

The critical role of GRP78 in physiologic and pathologic stress

(2010) Kyle T Pfaffenbach et al.   CURRENT OPINION IN CELL BIOLOGY

Endoplasmic reticulum stress: a new actor in the development of hepatic steatosis

(2010) Mélissa Flamment et al.   CURRENT OPINION IN LIPIDOLOGY

Insulin modulates induction of glucose-regulated protein 78 during endoplasmic reticulum stress via augmentation of ATF4 expression in human neuroblastoma cells

(2010) Kiyoshi Inageda   FEBS LETTERS

Cell Surface Relocalization of the Endoplasmic Reticulum Chaperone and Unfolded Protein Response Regulator GRP78/BiP

(2010) Yi Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A regulatory subunit of phosphoinositide 3-kinase increases the nuclear accumulation of X-box–binding protein-1 to modulate the unfolded protein response

(2010) Jonathon N Winnay et al.   NATURE MEDICINE

The regulatory subunits of PI3K, p85α and p85β, interact with XBP-1 and increase its nuclear translocation

(2010) Sang Won Park et al.   NATURE MEDICINE

Reprint of: Metabolic effects and mechanism of action of the chromogranin A-derived peptide pancreastatin

(2010) Víctor Sánchez-Margalet et al.   REGULATORY PEPTIDES

Role of the Unfolded Protein Response Regulator GRP78/BiP in Development, Cancer, and Neurological Disorders

(2009) Miao Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

Modulation of the unfolded protein response in prostate cancer cells by antibody-directed against the carboxyl-terminal domain of GRP78

(2009) U. K. Misra et al.   APOPTOSIS

Grp78 Heterozygosity Promotes Adaptive Unfolded Protein Response and Attenuates Diet-Induced Obesity and Insulin Resistance

(2009) R. Ye et al.   DIABETES

A Novel Pathway of Insulin Sensitivity in Chromogranin A Null Mice

(2009) Jiaur R. Gayen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

GRP78 expression inhibits insulin and ER stress–induced SREBP-1c activation and reduces hepatic steatosis in mice

(2009) Hélène L. Kammoun et al.   JOURNAL OF CLINICAL INVESTIGATION

Global metabolic consequences of the chromogranin A-null model of hypertension: transcriptomic detection, pathway identification, and experimental verification

(2009) Ryan S. Friese et al.   PHYSIOLOGICAL GENOMICS

Regulation of PERK Signaling and Leukemic Cell Survival by a Novel Cytosolic Isoform of the UPR Regulator GRP78/BiP

(2009) Min Ni et al.   PLoS One

Insulin-like growth factor-I protects cells from ER stress-induced apoptosis via enhancement of the adaptive capacity of endoplasmic reticulum

(2008) R Novosyadlyy et al.   CELL DEATH AND DIFFERENTIATION

The Role for Endoplasmic Reticulum Stress in Diabetes Mellitus

(2008) Décio L. Eizirik et al.   ENDOCRINE REVIEWS