Inhibition of Calcineurin Abrogates While Inhibition of mTOR Promotes Regulatory T Cell Expansion and Graft-Versus-Host Disease Protection by IL-2 in Allogeneic Bone Marrow Transplantation

Differential targeting of IL-2 and T cell receptor signaling pathways selectively expands regulatory T cells while inhibiting conventional T cells

(2013) Atsushi Satake et al.   JOURNAL OF AUTOIMMUNITY

Cell-autonomous role of TGF  and IL-2 receptors in CD4+ and CD8+ inducible regulatory T-cell generation during GVHD

(2012) N. Sawamukai et al.   BLOOD

Identification and expansion of highly suppressive CD8+FoxP3+ regulatory T cells after experimental allogeneic bone marrow transplantation

(2012) R. J. Robb et al.   BLOOD

CD8+ Foxp3+ Regulatory T Cells Are Induced during Graft-versus-Host Disease and Mitigate Disease Severity

(2012) A. J. Beres et al.   JOURNAL OF IMMUNOLOGY

Rapamycin and IL-2 reduce lethal acute graft-versus-host disease associated with increased expansion of donor type CD4+CD25+Foxp3+ regulatory T cells

(2011) H.-J. Shin et al.   BLOOD

Regulatory T Cells Require Mammalian Target of Rapamycin Signaling To Maintain Both Homeostasis and Alloantigen-Driven Proliferation in Lymphocyte-Replete Mice

(2011) Y. Wang et al.   JOURNAL OF IMMUNOLOGY

Interleukin-2 and Regulatory T Cells in Graft-versus-Host Disease

(2011) John Koreth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cellular therapies supplement: the role of granulocyte macrophage colony-stimulating factor and dendritic cells in regulatory T-cell homeostasis and expansion

(2011) Tao Zou et al.   TRANSFUSION

Altered regulatory T cell homeostasis in patients with CD4+ lymphopenia following allogeneic hematopoietic stem cell transplantation

(2010) Ken-ichi Matsuoka et al.   JOURNAL OF CLINICAL INVESTIGATION

Dendritic Cells Induce Regulatory T Cell Proliferation through Antigen-Dependent and -Independent Interactions

(2010) T. Zou et al.   JOURNAL OF IMMUNOLOGY

Expansion of peripheral naturally occurring T regulatory cells by Fms-like tyrosine kinase 3 ligand treatment

(2009) L. K. Swee et al.   BLOOD

Control of Regulatory T Cell Lineage Commitment and Maintenance

(2009) Steven Z. Josefowicz et al.   IMMUNITY

Regulatory T Cells and Immune Tolerance

(2008) Shimon Sakaguchi et al.   CELL