The mTOR Pathway Controls Cell Proliferation by Regulating the FoxO3a Transcription Factor via SGK1 Kinase

AKT-ing out: SGK kinases come to the fore: Figure 1

(2013) Larissa S. Moniz et al.   BIOCHEMICAL JOURNAL

Elevated SGK1 predicts resistance of breast cancer cells to Akt inhibitors

(2013) Eeva M. Sommer et al.   BIOCHEMICAL JOURNAL

New insights into Notch1 regulation of the PI3K–AKT–mTOR1 signaling axis: Targeted therapy of γ-secretase inhibitor resistant T-cell acute lymphoblastic leukemia

(2013) Eric C. Hales et al.   CELLULAR SIGNALLING

Regulation of mTORC1 and its impact on gene expression at a glance

(2013) M. Laplante et al.   JOURNAL OF CELL SCIENCE

The lysosomal signaling anchor p18/LAMTOR1 controls epidermal development by regulating lysosome-mediated catabolic processes

(2013) T. Soma-Nagae et al.   JOURNAL OF CELL SCIENCE

Ragulator Is a GEF for the Rag GTPases that Signal Amino Acid Levels to mTORC1

(2012) Liron Bar-Peled et al.   CELL

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

Lysine methylation of FOXO3 regulates oxidative stress-induced neuronal cell death

(2012) Qi Xie et al.   EMBO REPORTS

Determination of SGK1 mRNA in non-small cell lung cancer samples underlines high expression in squamous cell carcinomas

(2012) Claudia Abbruzzese et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The Transcription Factor TFEB Links mTORC1 Signaling to Transcriptional Control of Lysosome Homeostasis

(2012) A. Roczniak-Ferguson et al.   Science Signaling

The late endosome/lysosome-anchored p18-mTORC1 pathway controls terminal maturation of lysosomes

(2011) Yusuke Takahashi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Interplay between FOXO, TOR, and Akt

(2011) Nissim Hay   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

FoxO transcription factors; Regulation by AKT and 14-3-3 proteins

(2011) Guri Tzivion et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Akt, FoxO and regulation of apoptosis

(2011) Xinbo Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Serum/glucocorticoid-regulated kinase 1 expression in primary human prostate cancers

(2011) Russell Z. Szmulewitz et al.   PROSTATE

Phosphoproteomic Analysis Identifies Grb10 as an mTORC1 Substrate That Negatively Regulates Insulin Signaling

(2011) Y. Yu et al.   SCIENCE

The mTOR-Regulated Phosphoproteome Reveals a Mechanism of mTORC1-Mediated Inhibition of Growth Factor Signaling

(2011) P. P. Hsu et al.   SCIENCE

Ragulator-Rag Complex Targets mTORC1 to the Lysosomal Surface and Is Necessary for Its Activation by Amino Acids

(2010) Yasemin Sancak et al.   CELL

FoxOs Inhibit mTORC1 and Activate Akt by Inducing the Expression of Sestrin3 and Rictor

(2010) Chia-Chen Chen et al.   DEVELOPMENTAL CELL

Second AKT: The rise of SGK in cancer signalling

(2010) Maressa A. Bruhn et al.   GROWTH FACTORS

Colorectal carcinoma cells—Regulation of survival and growth by SGK1

(2010) Florian Lang et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Rictor Forms a Complex with Cullin-1 to Promote SGK1 Ubiquitination and Destruction

(2010) Daming Gao et al.   MOLECULAR CELL

Epigenetics in Women's Health Care

(2010) Yevgeniya Pozharny et al.   MOUNT SINAI JOURNAL OF MEDICINE

An Emerging Role of mTOR in Lipid Biosynthesis

(2009) Mathieu Laplante et al.   CURRENT BIOLOGY

The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK–ERK pathway to late endosomes

(2009) Shigeyki Nada et al.   EMBO JOURNAL

mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)

(2008) Juan M. García-Martínez et al.   BIOCHEMICAL JOURNAL

Arginine Methylation of FOXO Transcription Factors Inhibits Their Phosphorylation by Akt

(2008) Kazuyuki Yamagata et al.   MOLECULAR CELL

The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1

(2008) Y. Sancak et al.   SCIENCE