Increasing Prion Propensity by Hydrophobic Insertion

Discovering putative prion sequences in complete proteomes using probabilistic representations of Q/N-rich domains

(2013) Vladimir Espinosa Angarica et al.   BMC GENOMICS

Stress granules as crucibles of ALS pathogenesis

(2013) Yun R. Li et al.   JOURNAL OF CELL BIOLOGY

Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS

(2013) Hong Joo Kim et al.   NATURE

The Effects of Amino Acid Composition of Glutamine-Rich Domains on Amyloid Formation and Fragmentation

(2012) Alexander I. Alexandrov et al.   PLoS One

Strategies for identifying new prions in yeast

(2012) Kyle S. MacLea et al.   Prion

Prion formation by a yeast GLFG nucleoporin

(2012) Randal Halfmann et al.   Prion

De novo design of synthetic prion domains

(2012) J. A. Toombs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations

(2011) Manuela Neumann et al.   BRAIN

Understanding the role of TDP-43 and FUS/TLS in ALS and beyond

(2011) Sandrine Da Cruz et al.   CURRENT OPINION IN NEUROBIOLOGY

A Small, Glutamine-Free Domain Propagates the [SWI+] Prion in Budding Yeast

(2011) E. T. Crow et al.   MOLECULAR AND CELLULAR BIOLOGY

[PSI+] Maintenance Is Dependent on the Composition, Not Primary Sequence, of the Oligopeptide Repeat Domain

(2011) James A. Toombs et al.   PLoS One

A yeast functional screen predicts new candidate ALS disease genes

(2011) J. Couthouis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Suicidal [PSI+] is a lethal yeast prion

(2011) R. P. McGlinchey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic and epigenetic control of the efficiency and fidelity of cross-species prion transmission

(2010) Buxin Chen et al.   MOLECULAR MICROBIOLOGY

Exploring the sequence determinants of amyloid structure using position-specific scoring matrices

(2010) Sebastian Maurer-Stroh et al.   NATURE METHODS

The effects of amino acid composition on yeast prion formation and prion domain interactions

(2010) Eric D. Ross et al.   Prion

Identifying the amylome, proteins capable of forming amyloid-like fibrils

(2010) Lukasz Goldschmidt et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Systematic Survey Identifies Prions and Illuminates Sequence Features of Prionogenic Proteins

(2009) Simon Alberti et al.   CELL

A Promiscuous Prion: Efficient Induction of [URE3] Prion Formation by Heterologous Prion Domains

(2009) C. D. Ross et al.   GENETICS

The Spontaneous Appearance Rate of the Yeast Prion [PSI+] and Its Implications for the Evolution of the Evolvability Properties of the [PSI+] System

(2009) A. K. Lancaster et al.   GENETICS

Amyotrophic lateral sclerosis, frontotemporal dementia and beyond: the TDP-43 diseases

(2009) Felix Geser et al.   JOURNAL OF NEUROLOGY

Compositional Determinants of Prion Formation in Yeast

(2009) J. A. Toombs et al.   MOLECULAR AND CELLULAR BIOLOGY

Short protein segments can drive a non-fibrillizing protein into the amyloid state

(2009) P. K. Teng et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Appearance and Propagation of Polyglutamine-based Amyloids in Yeast

(2008) Ilya M. Alexandrov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prediction of Aggregation-Prone Regions in Structured Proteins

(2008) Gian Gaetano Tartaglia et al.   JOURNAL OF MOLECULAR BIOLOGY

TDP-43 accumulation in inclusion body myopathy muscle suggests a common pathogenic mechanism with frontotemporal dementia

(2008) C C Weihl et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY