XIAP Antagonist Embelin Inhibited Proliferation of Cholangiocarcinoma Cells

Monitoring Drug Target Engagement in Cells and Tissues Using the Cellular Thermal Shift Assay

(2013) D. M. Molina et al.   SCIENCE

Co-Expression of XIAP and Cyclin D1 Complex Correlates with a Poor Prognosis in Patients with Hepatocellular Carcinoma

(2012) Yufang Che et al.   AMERICAN JOURNAL OF PATHOLOGY

Embelin inhibits growth and induces apoptosis through the suppression of Akt/mTOR/S6K1 signaling cascades

(2012) Seong Won Kim et al.   PROSTATE

Embelin suppresses STAT3 signaling, proliferation, and survival of multiple myeloma via the protein tyrosine phosphatase PTEN

(2011) Ji Young Heo et al.   CANCER LETTERS

Characterization of Human OCT1-Mediated Transport of DAPI as a Fluorescent Probe Substrate

(2011) Tomoya Yasujima et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Hedgehog Inhibition Promotes a Switch from Type II to Type I Cell Death Receptor Signaling in Cancer Cells

(2011) Satoshi Kurita et al.   PLoS One

Evaluation of 4',6-Diamidino-2-phenylindole as a Fluorescent Probe Substrate for Rapid Assays of the Functionality of Human Multidrug and Toxin Extrusion Proteins

(2010) T. Yasujima et al.   DRUG METABOLISM AND DISPOSITION

Triptolide and TRAIL Combination Enhances Apoptosis in Cholangiocarcinoma

(2010) Kimberly A. Clawson et al.   JOURNAL OF SURGICAL RESEARCH

Embelin induces apoptosis through down-regulation of XIAP in human leukemia cells

(2010) Rong Hu et al.   MEDICAL ONCOLOGY

Cisplatin plus Gemcitabine versus Gemcitabine for Biliary Tract Cancer

(2010) Juan Valle et al.   NEW ENGLAND JOURNAL OF MEDICINE

The XIAP inhibitor Embelin enhances TRAIL-mediated apoptosis in malignant glioma cells by down-regulation of the short isoform of FLIP

(2009) M.D. Siegelin et al.   NEUROCHEMISTRY INTERNATIONAL

Trastuzumab signaling in ErbB2-overexpressing inflammatory breast cancer correlates with X-linked inhibitor of apoptosis protein expression

(2008) K. M. Aird et al.   MOLECULAR CANCER THERAPEUTICS